Abstract: The present invention relates to a method for treating diseases associated with type-1 interferon signaling. Particularly, the present invention is directed to use of specific inhibitors of Voltage-Dependent Anion Channel (VDAC1), such as piperazine- and/or piperidine-derivatives, among others, e.g., peptides and oligonucleotides, for treating an autoimmune disease.

Abstract: A solar cell includes an opto-electrical conversion structure, a first electrically-conductive structure, and a second electrically-conductive structure. The opto-electrical conversion structure has a light receiving surface and a back surface opposite to the light receiving surface. The first electrically-conductive structure is disposed on the light receiving surface and electrically connected to the opto-electrical conversion structure. The first electrically-conductive structure includes a first transparent electrically-conductive layer, an electrode structure, and a second transparent electrically-conductive layer. The first transparent electrically-conductive layer is disposed on the light receiving surface of the opto-electrical conversion structure. At least one portion of the first transparent electrically-conductive layer is disposed between the electrode structure and the light receiving surface of the opto-electrical conversion structure.

Abstract: 7-(3-Aminomethyl-4-methoxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate and hydrates thereof, processes for their preparation, pharmaceutical compositions comprising them, and their use in antibacterial therapy.

Abstract: A versatile laser pointer and mouse combination integrates together the functions of laser pointer and mouse, also preferably includes a presentation program operation function, multimedia player program operation function, and timer to provide users with versatile functions and operation convenience during computer aided presentations, such as lectures, speeches, and the like. Furthermore, the housing and key sets of the versatile laser pointer and mouse combination may be configured to maintain the ergonomics in terms of hand touch of a mouse to be maintained without affecting the convenience of operating all the other added functions.

Abstract: A laser level generates a first, a second and a third laser beam which are perpendicular to each other. The laser level includes a first laser generator for generating the first laser beam, a second laser generator for generating an incident laser beam, and a prism disposed in front of the second laser generator for splitting the incident laser beam into the second and the third laser beams. A plurality of vials are provided for indicating the level of the respective first, second and third laser beams, and a housing accommodates the first laser generator, the second laser generator, the prism and the vials.

Abstract: A simple cochlear implant is provided that avoids excavation of the mastoid bone. The cochlear implant includes one or more modules for housing the active and passive electronics, and an electrode array for stimulating the nerves of the cochlea. The cochlear implant may include a single modular unit which houses all of the electronics including processor, power supply and microphone. The single modular unit is positioned within the soft tissue behind the ear pinna. Alternatively, the cochlear implant includes two modular units. The first module is implanted within the soft tissue between the ear pinna and mastoid bone. Meanwhile, the second unit is an external module which may be positioned at various external locations. The exterior module may transmit electrical signals to the implanted module through various communication connections including direct electrical contact or through an electromagnetic link.