Abstract: A method of inhibiting propagation of protein misfolding associated with a neurological disease, is carried out by contacting an environment populated with a propagating amyloid conformation of a protein (prion) associated with a neurological disease with molecules which binds multiple adjacent sites of the protein assemblies and allowing the molecules to bind multiple cites of the protein assemblies; and thereby impeding propagation of the disease-associated conformation of the protein in the environment. Drug/prion complexes are formed and uses of the drugs in detection and treatment of neurodegenerative diseases are disclosed.

Abstract: A method for detecting a neurological disease the method comprising isolating brain tissue from its natural environment, contacting the brain tissue with a labeled molecule which binds to multiple sites of stacked proteins associated with neurodegenerative disease, determining the binding of the labeled molecule; and thereby determining a neurodegenerative disease associated with the brain tissue.

Abstract: The invention provides compounds, and methods of using those compounds to treat neurodegenerative diseases.

Abstract: A method or process for generating an attributable and trackable message based engagement through SMS or IP based messaging unit, from within a single unified campaign platform environment, between internet connected devices on any open or closed content delivery networks, servers, website, or social media sites such that the intent and messaging sequence may be tracked and attributed to campaigns, specified audiences, and ad platforms.

Abstract: A method or process for generating an attributable and trackable message based engagement through SMS or IP based messaging unit, from within a single unified campaign platform environment, between internet connected devices on any open or closed content delivery networks, servers, website, or social media sites such that the intent and messaging sequence may be tracked and attributed to campaigns, specified audiences, and ad platforms.

Abstract: A method or process for generating an attributable and trackable message based engagement through SMS or IP based messaging unit, from within a single unified campaign platform environment, between internet connected devices on any open or closed content delivery networks, servers, website, or social media sites such that the intent and messaging sequence may be tracked and attributed to campaigns, specified audiences, and ad platforms.

Abstract: A new class of compounds is disclosed that in preferred embodiments relate to Ru-based catalysts suitable for use in olefin metathesis reactions. Such compounds demonstrate high rates of catalytic turnover in comparison with other Ru catalysts known in the art. Moreover, the catalysts are highly stable, and readily suited to attachment to a solid support via the anionic ligands. The invention also pertains to methods of producing the catalysts, and their use in catalyzing olefin metathesis reactions.