Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A sprocket adapter configured to roll up a waste pad. The sprocket adapter includes a sprocket, a first tube, a second tube, and a set of fins. The first and second tubes extend from the sprocket configured to couple with the take-up rod. The set of fins extends from the first side of the sprocket to couple with a pet waste pad. An end cap is configured to removably couple to a sprocket adapter comprising an aperture having two slotted portions, and a set of flaps. The aperture fits around the first tube of a sprocket adapter. The two slotted portions fit around a set of fins of a sprocket adapter. The set of flaps couple to the sprocket adapter. A take-up rod is configured to couple with a sprocket adapter. A pet waste roll assembly comprises a sprocket adapter coupled to an end cap and a take-up rod.

Abstract: A control module that may be configured to detect animal activity of a pet at a waste pad, litter box, or feeding station. The control module comprises a sensor system having a camera. The control module is configured to analyze pet information and generate user data based on the pet information. Additionally, a mobile device is configured to detect animal activity within a field of view. The mobile device is configured to analyze pet information and generate user data based on the pet information.

Abstract: A control module that may be configured to detect animal activity of a pet at a waste pad, litter box, or feeding station. The control module comprises a sensor system having a camera. The control module is configured to analyze pet information and generate user data based on the pet information. Additionally, a mobile device is configured to detect animal activity within a field of view. The mobile device is configured to analyze pet information and generate user data based on the pet information.

Abstract: A control module that may be configured to detect animal activity of a pet at a waste pad, litter box, or feeding station. The control module comprises a sensor system having a camera. The control module is configured to analyze pet information and generate user data based on the pet information. Additionally, a mobile device is configured to detect animal activity within a field of view. The mobile device is configured to analyze pet information and generate user data based on the pet information.

Abstract: An infinitely variable transmission includes an input differential and an output differential. The input differential and the output differential both include differentially associated forward path and reverse path gear members. The forward path gear members are meshed indirectly through an idler gear and the reverse path gear members mesh directly to cause counter-rotation of the output differential gear members. The input differential gear members are controlled by a variator so that the forward path gear members may be regulated to rotate faster than the reverse path gear members to cause forward rotation of the output shaft, or so that the forward path gear members may be regulated to rotate slower than the reverse path gear members to cause reverse rotation of the output shaft or so that the forward and reverse path gear members rotate at the same speed to make the output shaft stationary.

Abstract: A locking device and apparatus is disclosed. The locking device is particularly suitable for use in combination with a device such as a track mounted gangway and safety cage to reduce the ability to reposition the gangway and safety cage along a track surface while in the lowered access position. The locking device preferably includes a lever assembly and a pivot assembly having a friction pad connected to the lever assembly. When the lever assembly and/or gangway device is adjusted in a first direction, the friction pad applies pressure on the track surface and moveability between the gangway and the track surface is reduced.

Abstract: A locking device and apparatus is disclosed. The locking device is particularly suitable for use in combination with a device such as a track mounted gangway and safety cage to reduce the ability to reposition the gangway and safety cage along a track surface while in the lowered access position. The locking device preferably includes a lever assembly and a pivot assembly having a friction pad connected to the lever assembly. When the lever assembly and/or gangway device is adjusted in a first direction, the friction pad applies pressure on the track surface and moveability between the gangway and the track surface is reduced.

Abstract: A locking device and apparatus is disclosed. The locking device is particularly suitable for use in combination with a device such as a track mounted gangway and safety cage to reduce the ability to reposition the gangway and safety cage along a track surface while in the lowered access position. The locking device preferably includes a lever assembly and a pivot assembly having a friction pad connected to the lever assembly. When the lever assembly and/or gangway device is adjusted in a first direction, the friction pad applies pressure on the track surface and moveability between the gangway and the track surface is reduced.

Abstract: A manual litter box provides various advantages over the prior art. In particular, in one embodiment, the manual litter box is configured to use a disposable cartridge which may include a litter compartment and a waste compartment. In another embodiment, the cartridge may be non-compartmentalized. The cartridge may be disposable, thus eliminating the need for the user to clean the litter tray and handle heavy litter containers. In other embodiments, the system includes a rake assembly configured with a manual shuttle chassis drive assembly that is protected from contamination. In accordance with another embodiment of the invention, the manual litter box is configured to be used with all types of litter including crystal type litter.

Abstract: A locking device and apparatus is disclosed. The locking device is particularly suitable for use in combination with a device such as a track mounted gangway and safety cage to reduce the ability to reposition the gangway and safety cage along a track surface while in the lowered access position. The locking device preferably includes a lever assembly and a pivot assembly having a friction pad connected to the lever assembly. When the lever assembly and/or gangway device is adjusted in a first direction, the friction pad applies pressure on the track surface and moveability between the gangway and the track surface is reduced.

Abstract: A locking device and apparatus is disclosed. The locking device is particularly suitable for use in combination with a device such as a track mounted gangway and safety cage to reduce the ability to reposition the gangway and safety cage along a track surface while in the lowered access position. The locking device preferably includes a lever assembly and a pivot assembly having a friction pad connected to the lever assembly. When the lever assembly and/or gangway device is adjusted in a first direction, the friction pad applies pressure on the track surface and moveability between the gangway and the track surface is reduced.

Abstract: A manual litter box is disclosed which provides various advantages over the prior art. In particular, in one embodiment, the manual litter box is configured to use a disposable cartridge which may include a litter compartment and a waste compartment. In another embodiment, the cartridge may be non-compartmentalized. The cartridge may be disposable, thus eliminating the need for the user to clean the litter tray and handle heavy litter containers. In other embodiments, the system includes a rake assembly configured with a manual shuttle chassis drive assembly that is protected from contamination. In accordance with another embodiment of the invention, the manual litter box is configured to be used with all types of litter including crystal type litter.

Abstract: A system and method for establishing associative relationships between properties of a contained object and corresponding parameters of a container application is disclosed herein. In one embodiment the present system contemplates the establishment of both mutual and unilateral associative relationships, with a particular relationship being specified via a user interface created upon instantiation of the contained object. The associative relationships may be advantageously established without modification of the code comprising the contained object.

Abstract: A manual litter box provides various advantages over the prior art. In particular, in one embodiment, the manual litter box is configured to use a disposable cartridge which may include a litter compartment and a waste compartment. In another embodiment, the cartridge may be non-compartmentalized. The cartridge may be disposable, thus eliminating the need for the user to clean the litter tray and handle heavy litter containers. In other embodiments, the system includes a rake assembly configured with a manual shuttle chassis drive assembly that is protected from contamination. In accordance with another embodiment of the invention, the manual litter box is configured to be used with all types of litter including crystal type litter.

Abstract: A self-cleaning litter box (50) provides various advantages over the prior art. In particular, in one embodiment, the self-cleaning litter box (50) is configured to use a one piece litter cartridge (20) having a litter compartment (26) and a waste compartment 24. In another embodiment, the cartridge (20) is non-compartmentalized. In another embodiment, the system includes a rake assembly (56) configured with a drive assembly (58) that is protected from waste contamination. In accordance with the invention, the self-cleaning litter box (50) is configured to be used with all types of litter including crystal type litter.