Patents by Inventor Jay D. Potts

Jay D. Potts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220257711
    Abstract: NMEG-?CGRP, a biologically active molecule, and systems and methods of use therefore, subcutaneous administration of NMEG-?CGRP, a non-toxic peptoid-peptide hybrid that possesses hypotensive action, employed as a therapeutic agent to treat and prevent various cardiovascular diseases, including, heart failure (pressure. as well as volume, overload), myocardial infarction, cardiomyopathy, and hypertension.
    Type: Application
    Filed: July 31, 2020
    Publication date: August 18, 2022
    Applicants: University of South Carolina, Board of Trustees of the University of Arkansas
    Inventors: Jay D. Potts, Ambrish Kumar, Donald Dipette, Shannon Servoss
  • Publication number: 20220259279
    Abstract: Methods and systems for delivering a very potent vasodilator that has the ability to treat and prevent heart failure including delivering microcapsules containing ?-CGRP, which show no toxicity and lowers blood pressure similar to the native peptide, where this new compound could greatly enhance the lifespan of patients suffering from heart failure.
    Type: Application
    Filed: July 31, 2020
    Publication date: August 18, 2022
    Applicant: University of South Carolina
    Inventors: Ambrish Kumar, Jay D. Potts, Donald J. Dipette, Marwa Belhaj
  • Patent number: 8815556
    Abstract: In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel structure and an isolated polypeptide having the carboxy-terminal amino acid sequence of an alpha Connexin, or a conservative variant thereof, wherein the polypeptide does not include the full length alpha Connexin protein.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: August 26, 2014
    Inventors: Robert G. Gourdie, Jay D. Potts
  • Publication number: 20130236431
    Abstract: In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel structure and an isolated polypeptide having the carboxy-terminal amino acid sequence of an alpha Connexin, or a conservative variant thereof, wherein the polypeptide does not include the full length alpha Connexin protein.
    Type: Application
    Filed: April 1, 2013
    Publication date: September 12, 2013
    Applicants: University of South Carolina, Medical University of South Carolina
    Inventors: Robert G. Gourdie, Jay D. Potts
  • Patent number: 8409603
    Abstract: In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel structure and an isolated polypeptide having the carboxy-terminal amino acid sequence of an alpha Connexin, or a conservative variant thereof, wherein the polypeptide does not include the full length alpha Connexin protein.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: April 2, 2013
    Assignees: University of South Carolina, Medical University of South Carolina
    Inventors: Robert G. Gourdie, Jay D. Potts
  • Publication number: 20110086068
    Abstract: In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel structure and an isolated polypeptide having the carboxy-terminal amino acid sequence of an alpha Connexin, or a conservative variant thereof, wherein the polypeptide does not include the full length alpha Connexin protein.
    Type: Application
    Filed: October 1, 2010
    Publication date: April 14, 2011
    Applicants: Medical University of South Carolina, University of South Carolina
    Inventors: Robert G. Gourdie, Jay D. Potts
  • Patent number: 7910066
    Abstract: A plate platform having a visual indicator that allows the user to track his or her progress in loading the platform wells is generally disclosed. The plate platform is constructed from a substantially transparent base having a plurality of elongated bore-holes internally from the side surface in the substantially transparent base. The substantially transparent base defines a non-transparent portion on the top surface extending from the side surface to an area configured to receive the well plate. A slide bar is positioned slideably positioned within each elongated bore-hole of the substantially transparent base. Each slide bar defines a marked surface that is visible through the substantially transparent base but not through the non-transparent portion. The marked surface comprises a row label, a column label, and a well marker.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: March 22, 2011
    Assignee: University of South Carolina
    Inventors: Jay D. Potts, Conrad Michael Gore
  • Publication number: 20100136694
    Abstract: A cone-shaped adapter for attachment to a muzzle of a gene gun is generally provided. The cone-shaped adapter comprises sidewalls that taper from a base plane at one end and to an apex aperture at an opposite end and a fitting. The sidewalls form a base angle of from about 85° to about 45° with the base plane. The fitting is attached to the sidewalls at the base plane and is configured to connect the cone-shaped adapter to the muzzle of the gene gun. Methods of using the cone-shaped adapter with a gene gun are also provided.
    Type: Application
    Filed: December 3, 2008
    Publication date: June 3, 2010
    Applicant: University of South Carolina
    Inventors: Jay D. Potts, Conrad Michael Gore
  • Publication number: 20090253195
    Abstract: A plate platform having a visual indicator that allows the user to track his or her progress in loading the platform wells is generally disclosed. The plate platform is constructed from a substantially transparent base having a plurality of elongated bore-holes internally from the side surface in the substantially transparent base. The substantially transparent base defines a non-transparent portion on the top surface extending from the side surface to an area configured to receive the well plate. A slide bar is positioned slideably positioned within each elongated bore-hole of the substantially transparent base. Each slide bar defines a marked surface that is visible through the substantially transparent base but not through the non-transparent portion. The marked surface comprises a row label, a column label, and a well marker.
    Type: Application
    Filed: April 4, 2008
    Publication date: October 8, 2009
    Inventors: Jay D. Potts, Conrad Michael Gore