Abstract: A composition includes at least one siloxy-based (meth)acrylate monomer or prepolymer, at least one additional methacrylate monomer, UV, and Visible light blocking agents and one or more crosslinking agents. The final product results in a highly wettable material that possesses physical properties such as a low modulus of elasticity and high oxygen permeability without the need for a non-reactive solubilizing agent and that are free of cyclic and linear siloxanes.

Abstract: Hydrogel materials used in the manufacture of biocompatible medical devices, for example, hydrogel materials having desirable physical properties for use as a contact lens. A composition contains at least one vinyl containing monomer, a methacrylate(acrylate) monomer, methacrylate (acrylate) prepolymers, crosslinking agents and monomers having the structure as shown in Formula 1: where R1 is a vinyl functionality capable of radical polymerization with specific preference for N-vinyl lactam derivatives and R2 is a zwitterionic functionality. The materials utilize a two-phase polymerization strategy.

Abstract: A composition includes at least one siloxy-based (meth)acrylate monomer or prepolymer, at least one additional methacrylate monomer, UV, and Visible light blocking agents and one or more crosslinking agents. The final product results in a highly wettable material that possesses physical properties such as a low modulus of elasticity and high oxygen permeability without the need for a non-reactive solubilizing agent and that are free of cyclic and linear siloxanes.

Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, which exhibit little or no scattering loss. The method can he used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, which exhibit little or no scattering loss and are characterized by a positive change in refractive index.

Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, which exhibit little or no scattering loss. The method can he used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, which exhibit little or no scattering loss and are characterized by a positive change in refractive index.

Abstract: Provided herein is a polymerized product formed of a polymerized monomer mixture comprising intentionally added water and at least one hydrophilic monomer wherein the monomer mix does not contain any silicon containing materials. The polymerized monomer mixture of the invention herein is useful in many biomaterial applications. Especially preferred is the use of the biomaterial as a hydrogel contact lens.

Abstract: A method of preparing a water extractable silicon-containing biomedical device is disclosed. The method involves curing a monomer mixture comprising one or more silicon-containing biomedical device-forming monomers in the presence of a diluent to produce a silicon-containing biomedical device; wherein the diluent comprises a boric acid ester of a C1 to C8 monohydric alcohol.

Abstract: A method of preparing a water extractable silicon-containing biomedical device is disclosed. The method involves curing a monomer mixture comprising one or more silicon-containing biomedical device-forming monomers in the presence of a diluent to produce a silicon-containing biomedical device; wherein the diluent comprises a boric acid ester of a C1 to C8 monohydric alcohol.

Abstract: A polymerizable monomer mixture containing one or more silicon-containing biomedical device-forming monomers and a diluent; wherein the diluent comprises a boric acid ester of a monohydric alcohol is disclosed.

Abstract: Provided herein is a polymerized product formed of a polymerized monomer mixture comprising intentionally added water and at least one hydrophilic monomer wherein the monomer mix does not contain any silicon containing materials. The polymerized monomer mixture of the invention herein is useful in many biomaterial applications. Especially preferred is the use of the biomaterial as a hydrogel contact lens.

Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, which exhibit little or no scattering loss. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, which exhibit little or no scattering loss and are characterized by a positive change in refractive index.