Patents by Inventor Jay GOPALAKRISHNAN

Jay GOPALAKRISHNAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE GENERATION OF NEUROSPHERES
    Publication number: 20230399612
    Abstract: The present invention relates to a method for producing a plurality of homogeneous neurospheres, said method comprising: providing pluripotent cells; seeding said pluripotent cells into a cell culture device comprising at least one compartment comprising a plurality of microwells; and culturing said pluripotent cells in said cell culture device under conditions that allow the cells to form neurospheres.
    Type: Application
    Filed: November 2, 2021
    Publication date: December 14, 2023
    Inventor: Jay GOPALAKRISHNAN
  • Composite 3D Brain Organoids with Optic Structures, Uses Thereof and Culture Medium for Obtaining Them
    Publication number: 20230210906
    Abstract: The present invention relates to 3D brain organoids, uses thereof, methods and culture medium for generating such organoids. An aspect of the invention provides brain organoids and methods of generating such organoids with bilaterally symmetric optic vesicles, containing both neuronal and non-neuronal cell types, and exhibiting functional circuitry. These organoids can be generated within short time intervals (e.g., 50 days) and therefore are useful for medical modelling and applications.
    Type: Application
    Filed: January 6, 2022
    Publication date: July 6, 2023
    Inventors: Jay GOPALAKRISHNAN, Elke GABRIEL, Aruljothi MARIAPPAN, Anand RAMANI
  • CPAP-tubulin module
    Patent number: 10875856
    Abstract: The invention relates to CPAP-tubulin inhibitors having the general formula (1) or a physiologically acceptable salt thereof; and their use as cancer therapeutics.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: December 29, 2020
    Assignees: UNIVERSITAET ZU KOELN, HELMHOLTZ ZENTRUM MUENCHEN
    Inventors: Kamyar Hadian, Karl Kenji Schorpp, Michael Sattler, Komal Soni, Jay Gopalakrishnan
  • CPAP-TUBULIN MODULE
    Publication number: 20180362527
    Abstract: The invention relates to CPAP-tubulin inhibitors having the general formula (1) or a physiologically acceptable salt thereof; and their use as cancer therapeutics.
    Type: Application
    Filed: December 8, 2016
    Publication date: December 20, 2018
    Applicants: UNIVERSITAET ZU KOELN, HELMHOLTZ ZENTRUM MUENCHEN
    Inventors: Kamyar HADIAN, Karl Kenji SCHORPP, Michael SATTLER, Soni KOMAL, Jay GOPALAKRISHNAN