Patents by Inventor JAY MADAN

JAY MADAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of cancer with larazotide derivatives in combination with immune checkpoint inhibitors
    Patent number: 11278587
    Abstract: The present invention provides compositions and methods for treating a patient having cancer, as well as methods for potentiating an immune checkpoint inhibitor therapy. The methods comprise administering larazotide or a derivative thereof such as (d)-larazotide to a subject in need, including subjects undergoing checkpoint inhibitor therapy, and subjects scheduled to undergo immune checkpoint inhibitor therapy.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: March 22, 2022
    Assignee: 9 METERS BIOPHARMA, INC.
    Inventors: Jay Madan, Sandeep Laumas
  • COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE CHECKPOINT INHIBITOR THERAPY
    Publication number: 20210361734
    Abstract: The present invention provides compositions and methods for treating a patient having cancer, as well as methods for potentiating an immune checkpoint inhibitor therapy. The methods comprise administering larazotide or a derivative thereof to a subject in need, including subjects undergoing checkpoint inhibitor therapy, and subjects scheduled to undergo immune checkpoint inhibitor therapy.
    Type: Application
    Filed: March 19, 2019
    Publication date: November 25, 2021
    Inventors: Jay MADAN, Sandeep LAUMAS
  • COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH PERMEABILITY OF INTESTINAL EPITHELIUM
    Publication number: 20210299481
    Abstract: The present invention provides methods for treating disorders associated with intestinal barrier dysfunction and increased intestinal permeability. The invention involves administering an effective amount larazotide or a larazotide derivative to a subject or a patient in need thereof.
    Type: Application
    Filed: June 10, 2021
    Publication date: September 30, 2021
    Inventors: JAY MADAN, ANTHONY BLIKSLAGER, Sandeep Laumas
  • COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE CHECKPOINT INHIBITOR THERAPY
    Publication number: 20210236586
    Abstract: The present invention provides compositions and methods for treating a patient having cancer, as well as methods for potentiating an immune checkpoint inhibitor therapy. The methods comprise administering larazotide or a derivative thereof such as (d)-larazotide to a subject in need, including subjects undergoing checkpoint inhibitor therapy, and subjects scheduled to undergo immune checkpoint inhibitor therapy.
    Type: Application
    Filed: April 23, 2021
    Publication date: August 5, 2021
    Inventors: Jay MADAN, Sandeep LAUMAS
  • COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE CHECKPOINT INHIBITOR THERAPY
    Publication number: 20210169968
    Abstract: The present invention provides compositions and methods for treating a patient having cancer, as well as methods for potentiating an immune checkpoint inhibitor therapy. The methods comprise administering larazotide or a derivative thereof such as (d)-larazotide to a subject in need, including subjects undergoing checkpoint inhibitor therapy, and subjects scheduled to undergo immune checkpoint inhibitor therapy.
    Type: Application
    Filed: February 10, 2021
    Publication date: June 10, 2021
    Inventors: Jay MADAN, Sandeep LAUMAS
  • COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH PERMEABILITY OF INTESTINAL EPITHELIUM
    Publication number: 20190358289
    Abstract: The present invention provides methods for treating disorders associated with intestinal barrier dysfunction and increased intestinal permeability. The invention involves administering an effective amount larazotide or a larazotide derivative to a subject or a patient in need thereof.
    Type: Application
    Filed: February 12, 2018
    Publication date: November 28, 2019
    Inventors: JAY MADAN, ANTHONY BLIKSLAGER
  • COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ENVIRONMENTAL ENTEROPATHY
    Publication number: 20190358288
    Abstract: The present invention provides compositions and methods for treating or preventing environmental enteropathy and associated intestinal damage. The compositions comprise Larazotide or Larazotide derivatives.
    Type: Application
    Filed: February 12, 2018
    Publication date: November 28, 2019
    Inventors: JAY MADAN, OSCAR COLIN STINE