Patents by Inventor Jay Mei

Jay Mei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ANTI-GPRC5D ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND GPRC5D AND CD3, AND USES THEREOF
    Publication number: 20250368734
    Abstract: The present disclosure provides anti-GPRC5D antibodies or antigen-binding fragments thereof, bispecific antigen binding molecules that bind GPRC5D and CD3, isolated polynucleotides encoding the same, pharmaceutical composition comprising the same and the uses thereof.
    Type: Application
    Filed: May 25, 2023
    Publication date: December 4, 2025
    Inventors: Hui YUWEN, Tengteng LI, Yijing REN, Peng CHEN, Bing HOU, Bo SHAN, Jay MEI
  • NOVEL ANTI-LILRB4 ANTIBODIES AND USES THEREOF
    Publication number: 20250361295
    Abstract: The present disclosure provides anti-LILRB4 antibodies or antigen-binding fragments thereof, pharmaceutical composition comprising the same and the uses thereof.
    Type: Application
    Filed: June 5, 2023
    Publication date: November 27, 2025
    Inventors: Ao SUN, Enlin ZHENG, Mengshi GAO, Suya BAI, Peng CHEN, Hui YUWEN, Bing HOU, Bo SHAN, Jay MEI
  • NOVEL ANTI-CD3 ANTIBODIES AND USES THEREOF
    Publication number: 20250223358
    Abstract: Provided are anti-CD3 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical composition comprising the same and the uses thereof.
    Type: Application
    Filed: March 7, 2023
    Publication date: July 10, 2025
    Inventors: Hui YUWEN, Yijing REN, Tengteng LI, Peng CHEN, Bing HOU, Bo SHAN, Jay MEI
  • PRMT5 INHIBITING COMPOUNDS AND USES THEREOF
    Publication number: 20250206749
    Abstract: The present application provides novel PRMT5 and/or MTA-cooperative PRMT5 inhibiting compounds, or pharmaceutically acceptable salts thereof. The present application also provides pharmaceutical compositions comprising one or more of the compounds, or pharmaceutically acceptable salts thereof as an active ingredient, and the use of the compounds, or pharmaceutically acceptable salts thereof in the treatment of diseases or disorders, including cancers.
    Type: Application
    Filed: March 14, 2025
    Publication date: June 26, 2025
    Inventors: Ming ZHANG, Ya KONG, Lulu JIANG, Bin JIANG, Guoqiang DAI, Yulong HE, Bing HOU, Bo SHAN, Jay MEI
  • PRMT5 inhibiting compounds and uses thereof
    Patent number: 12312357
    Abstract: The present application provides novel PRMT5 and/or MTA-cooperative PRMT5 inhibiting compounds, or pharmaceutically acceptable salts thereof. The present application also provides pharmaceutical compositions comprising one or more of the compounds, or pharmaceutically acceptable salts thereof as an active ingredient, and the use of the compounds, or pharmaceutically acceptable salts thereof in the treatment of diseases or disorders, including cancers.
    Type: Grant
    Filed: February 28, 2024
    Date of Patent: May 27, 2025
    Assignee: ANTENGENE DISCOVERY LIMITED
    Inventors: Ming Zhang, Ya Kong, Lulu Jiang, Bin Jiang, Guoqiang Dai, Yulong He, Bing Hou, Bo Shan, Jay Mei
  • NOVEL ANTI-CD276 ANTIBODIES AND THE USES THEREOF
    Publication number: 20240400689
    Abstract: Provided are anti-CD276 antibodies, and anti-CD276/PD-L1 bispecific antibody molecules, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.
    Type: Application
    Filed: May 11, 2022
    Publication date: December 5, 2024
    Inventors: Hui YUWEN, Bing HOU, Tenteng LI, Peng CHEN, Min DENG, Bo SHAN, Jay MEI
  • PRMT5 INHIBITING COMPOUNDS AND USES THEREOF
    Publication number: 20240262835
    Abstract: The present application provides novel PRMT5 and/or MTA-cooperative PRMT5 inhibiting compounds, or pharmaceutically acceptable salts thereof. The present application also provides pharmaceutical compositions comprising one or more of the compounds, or pharmaceutically acceptable salts thereof as an active ingredient, and the use of the compounds, or pharmaceutically acceptable salts thereof in the treatment of diseases or disorders, including cancers.
    Type: Application
    Filed: February 28, 2024
    Publication date: August 8, 2024
    Inventors: Ming ZHANG, Ya KONG, Lulu JIANG, Bin JIANG, Guoqiang DAI, Yulong HE, Bing HOU, Bo SHAN, Jay MEI
  • NOVEL ANTI-CD24 ANTIBODIES
    Publication number: 20240052052
    Abstract: The present disclosure provides anti-CD24 antibody, and anti-CD24/CD47 bispecific antibody molecules, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof
    Type: Application
    Filed: February 8, 2022
    Publication date: February 15, 2024
    Inventors: Peng CHEN, Bing HOU, Min DENG, Yun LIU, Jiamei LUO, Hui YUWEN, Bo SHAN, Jay MEI
  • ATR INHIBITORS AND USES THEREOF
    Publication number: 20230339927
    Abstract: The present disclosure relates to novel compounds useful as inhibitors of ATR kinase, as well as pharmaceutical compositions comprising these compounds and methods of treatment by administration of these compounds or the pharmaceutical compositions.
    Type: Application
    Filed: July 2, 2021
    Publication date: October 26, 2023
    Inventors: Bo SHAN, Bing HOU, Hui YUWEN, Zhongyang SHI, Peng CHEN, Jay MEI
  • ATR INHIBITORS AND USES THEREOF
    Publication number: 20230295166
    Abstract: The present disclosure relates to novel compounds useful as inhibitors of ATR kinase, as well as pharmaceutical compositions comprising these compounds and methods of treatment by administration of these compounds or the pharmaceutical compositions.
    Type: Application
    Filed: August 6, 2021
    Publication date: September 21, 2023
    Inventors: Bo SHAN, Bing HOU, Hui YUWEN, Peng CHEN, Zhongyang SHI, Zhengsong GU, Ping CHEN, Zhenwei CAI, Jay MEI
  • INHIBITORS OF KRAS G12C PROTEIN AND USES THEREOF
    Publication number: 20230212170
    Abstract: Provided are novel compounds useful as inhibitors of the KRAS protein, as well as pharmaceutical compositions comprising these compounds and methods of treatment by administration of these compounds or the pharmaceutical compositions.
    Type: Application
    Filed: June 3, 2021
    Publication date: July 6, 2023
    Inventors: Bo SHAN, Jian WANG, Bing HOU, Zhongyang SHI, Peng CHEN, Hui YUWEN, Xingquan MA, Zhu DU, Jay MEI
  • ANTIBODIES AND METHODS FOR TREATING CLAUDIN-ASSOCIATED DISEASES
    Publication number: 20230095569
    Abstract: Provided are anti-CLDN18 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.
    Type: Application
    Filed: June 23, 2021
    Publication date: March 30, 2023
    Inventors: Bin HOU, Peng CHEN, Hui YUWEN, Bo SHAN, Jay MEI
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20170216432
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 11, 2016
    Publication date: August 3, 2017
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • Methods of treating a disease or disorder associated with Bruton'S Tyrosine Kinase
    Patent number: 9492471
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: November 15, 2016
    Assignee: Celgene Avilomics Research, Inc.
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20150139979
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 21, 2015
    Applicant: Celgene Avilomics Research, Inc.
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20150064172
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 5, 2015
    Applicant: Celgene Avilomics Research, Inc.
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20150064173
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 5, 2015
    Applicant: Celgene Avilomics Research, Inc.
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20140140991
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 22, 2014
    Applicant: Celgene Avilomics Research, Inc.
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20140142129
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 22, 2014
    Applicant: Celgene Avilomics Research, Inc,
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei
  • METHODS OF TREATING A DISEASE OR DISORDER ASSOCIATED WITH BRUTON'S TYROSINE KINASE
    Publication number: 20140142128
    Abstract: The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 22, 2014
    Applicant: Celgene Avilomics Research, Inc.
    Inventors: Tom Daniel, Kenichi Takeshita, Kenneth Foon, Jay Mei