Patents by Inventor Jay Nguyen
Jay Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11964989Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.Type: GrantFiled: July 20, 2022Date of Patent: April 23, 2024Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
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Publication number: 20240110463Abstract: A wellhead bracing system for a subsea well includes a base plate assembly and a wellhead brace assembly. The base plate assembly comprises a top surface, a bottom surface, a base plate aperture, and a plurality of anchor holes. The wellhead brace assembly comprises a vertical plate assembly having a cylindrical shape, a horizontal plate assembly to which the vertical plate assembly is attached, and a vertical support assembly attached to an outer surface of the vertical plate assembly and attached to the top surface of the horizontal plate assembly. Horizontal plate holes of the horizontal plate assembly are configured to attach to studs on the top surface of the base plate to secure the wellhead brace assembly to the base plate assembly. The wellhead bracing system slides onto a wellhead of the subsea well and braces an exterior of the wellhead.Type: ApplicationFiled: September 23, 2023Publication date: April 4, 2024Inventors: Wangming Lu, Khiem Nguyen, Jay Patrick Painter, Caleb Kimbrell Carroll, William Stephen Averill, Deryck Edward Matthew Williams, David Crenshaw Barrow, Michael Ryan Fitzsimmons
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Patent number: 11931528Abstract: A catheter configured to dynamically compensate for the impact of internal and external forces that act upon the catheter during use is disclosed. The catheter may include sensors configured to measure received forces on control cables that extend within the catheter. A controller, coupled to the sensors, may record received force measurements associated with a working position of a distal end of the catheter. The controller may monitor subsequently received forces to identify force variances that may deflect the distal end of the catheter from its working position and may apply a driving force to one or more of the control cables to minimize the force variances. Monitoring received forces during use and applying compensating drive forces may reduce deflection of the distal end of the catheter, increasing the accuracy and precision of an annuloplasty procedure while minimizing potential damage to cardiac tissue.Type: GrantFiled: June 3, 2020Date of Patent: March 19, 2024Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: James P. Rohl, Aaron Abbott, Daniel Shuey, Joel T. Eggert, James K. Cawthra, Jr., Jay E. Daley, Christopher Nguyen
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Patent number: 8829094Abstract: A blown film composition including an impact copolymer polypropylene component and a nucleating agent, wherein the blown film has improved processing and physical properties.Type: GrantFiled: November 14, 2012Date of Patent: September 9, 2014Assignee: Fina Technology, Inc.Inventors: Ruby L. Curtis, Mark Leland, John Ashbaugh, Jay Nguyen
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Publication number: 20130165571Abstract: A blown film composition including an impact copolymer polypropylene component and a nucleating agent, wherein the blown film has improved processing and physical properties.Type: ApplicationFiled: November 14, 2012Publication date: June 27, 2013Inventors: Sam Curtis, Mark Leland, John Ashbaugh, Jay Nguyen
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Patent number: 8168112Abstract: Blown films and processes of forming the same are described herein. The processes generally include providing a bimodal ethylene based polymer, blending the bimodal ethylene based polymer with at least about 30 ppm peroxide to form modified polyethylene and forming the modified polyethylene into a blown film.Type: GrantFiled: December 20, 2008Date of Patent: May 1, 2012Assignee: Fina Technology, Inc.Inventors: Cyril Chevillard, Jay Nguyen
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Patent number: 8026305Abstract: Polymer articles and processes of forming the same are described herein. The processes generally include providing an ethylene based polymer, blending the ethylene based polymer with a modifier to form modified polyethylene and forming the modified polyethylene into a polymer article, wherein the polymer article exhibits a haze that is at least about 10% less than a polymer article prepared with a similarly modified polyethylene.Type: GrantFiled: October 1, 2008Date of Patent: September 27, 2011Assignee: Fina Technology IncInventors: Michael McLeod, John Ashbaugh, Cyril Chevillard, Gerhard Guenther, Ruby L. Curtis, Jay Nguyen, Juan Aguirre, Raleigh McBride, Ben Hicks
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Publication number: 20110105691Abstract: Polymer blends and methods of forming the same are described herein. The polymer blends generally include a single site transition metal catalyst formed polypropylene, a single site transition metal catalyst formed polyethylene and a polyethylene compatible nucleator.Type: ApplicationFiled: November 3, 2009Publication date: May 5, 2011Applicant: Fina Technology, Inc.Inventors: Michael McLeod, Jay Nguyen, John Ashbaugh
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Publication number: 20100160570Abstract: Blown films and processes of forming the same are described herein. The processes generally include providing a bimodal ethylene based polymer, blending the bimodal ethylene based polymer with at least about 30 ppm peroxide to form modified polyethylene and forming the modified polyethylene into a blown film.Type: ApplicationFiled: December 20, 2008Publication date: June 24, 2010Applicant: Fina Technology, Inc.Inventors: Cyril Chevillard, Jay Nguyen
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Publication number: 20100081767Abstract: Polymer articles and processes of forming the same are described herein. The processes generally include providing an ethylene based polymer, blending the ethylene based polymer with a modifier to form modified polyethylene and forming the modified polyethylene into a polymer article, wherein the polymer article exhibits a haze that is at least about 10% less than a polymer article prepared with a similarly modified polyethylene.Type: ApplicationFiled: October 1, 2008Publication date: April 1, 2010Applicant: Fina Technology, Inc.Inventors: Michael McLeod, John Ashbaugh, Cyril Chevillard, Gerhard Guenthar, Ruby Curtis, Jay Nguyen, Juan Aguirre, Raleigh McBride, Ben Hicks
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Publication number: 20060202377Abstract: A process for the production of partially oriented polypropylene fibers from syndiotactic polypropylene. Syndiotactic polypropylene is heated to a molten state and extruded to form a fiber preform. The fiber preform is spun at a forward spinning speed within the range of about 700-3500 meters per minute to produce a partially oriented fiber. The partially oriented fiber is wound without further substantial orientation of the fiber at a draw ratio of less than 1.5. By operating at a forward spinning speed of about 700 meters per minute or more, the partially oriented fiber has a greater tenacity than would be observed for a fiber formed from a corresponding spun isotactic polypropylene. The fiber preform is spun at a forward spinning speed of at least 100 meters per minute to provide a tenacity on the order of about 2 grams per denier or more. The fiber preform may be spun at a forward spinning speed of at least 1500 meters per minute to provide a tenacity of about 3 grams per denier.Type: ApplicationFiled: December 22, 2005Publication date: September 14, 2006Inventors: Mohan Gownder, Jay Nguyen
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Patent number: 7087301Abstract: Bicomponent fibers of syndiotactic polypropylene and ethylene-propylene random copolymer, can be prepared. The bicomponent fibers may exhibit self-crimp properties and high shrinkage characteristics.Type: GrantFiled: December 16, 2004Date of Patent: August 8, 2006Assignee: Fina Technology, Inc.Inventors: Michael Musgrave, Mohan R. Gownder, Jay Nguyen
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Patent number: 7081285Abstract: Blown films and blow molded objects may be prepared using a polyethylene composition comprising a unimodal metallocene catalyzed polyethylene copolymer. The polyethylene copolymer has high melt fow rate and good melt strength allowing it to be useful in both extrusion and injection blow molding. Blown film prepared therewith has a high level of clarity.Type: GrantFiled: April 29, 2005Date of Patent: July 25, 2006Assignee: Fina Technology, Inc.Inventors: Vincent Henri Barre, Tim Coffy, Ben Hicks, Rodolfo Mier, Jay Nguyen
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Publication number: 20060110598Abstract: Bicomponent fibers of syndiotactic polypropylene and ethylene-propylene random copolymer, can be prepared. The bicomponent fibers may exhibit self-crimp properties and high shrinkage characteristics.Type: ApplicationFiled: December 16, 2004Publication date: May 25, 2006Applicant: Fina Technology, Inc.Inventors: Michael Musgrave, Mohan Gownder, Jay Nguyen
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Patent number: 7025919Abstract: A process for the production of partially oriented polypropylene fibers from syndiotactic polypropylene. Syndiotactic polypropylene is heated to a molten state and extruded to form a fiber preform. The fiber preform is spun at a forward spinning speed within the range of about 700–3500 meters per minute to produce a partially oriented fiber. The partially oriented fiber is wound without further substantial orientation of the fiber at a draw ratio of less than 1.5. By operating at a forward spinning speed of about 700 meters per minute or more, the partially oriented fiber has a greater tenacity than would be observed for a fiber formed from a corresponding spun isotactic polypropylene. The fiber preform is spun at a forward spinning speed of at least 100 meters per minute to provide a tenacity on the order of about 2 grams per denier or more. The fiber preform may be spun at a forward spinning speed of at least 1500 meters per minute to provide a tenacity of about 3 grams per denier.Type: GrantFiled: March 28, 2002Date of Patent: April 11, 2006Assignee: Fina Technology, Inc.Inventors: Mohan Gownder, Jay Nguyen
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Publication number: 20050175835Abstract: Bicomponent fibers of syndiotactic polypropylene and ethylene-propylene random copolymer, can be prepared. The bicomponent fibers may exhibit self-crimp properties and high shrinkage characteristics.Type: ApplicationFiled: December 16, 2004Publication date: August 11, 2005Applicant: Fina Technology, Inc.Inventors: Michael Musgrave, Mohan Gownder, Jay Nguyen
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Publication number: 20050031863Abstract: Bicomponent fibers of isotactic polypropylene and syndiotactic polypropylene, methods of making such fibers and products made thereof are disclosed. Embodiments of the bicomponent fibers can exhibit self-crimp properties and high shrinkage characteristics.Type: ApplicationFiled: August 6, 2003Publication date: February 10, 2005Inventors: Mohan Gownder, Michael Musgrave, Jay Nguyen
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Patent number: 6846561Abstract: Bicomponent fibers of isotactic polypropylene and syndiotactic polypropylene, methods of making such fibers and products made thereof are disclosed. Embodiments of the bicomponent fibers can exhibit self-crimp properties and high shrinkage characteristics.Type: GrantFiled: August 6, 2003Date of Patent: January 25, 2005Assignee: Fina Technology, Inc.Inventors: Mohan R. Gownder, Michael Musgrave, Jay Nguyen
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Publication number: 20030187174Abstract: A process for the production of partially oriented polypropylene fibers from syndiotactic polypropylene. Syndiotactic polypropylene is heated to a molten state and extruded to form a fiber preform. The fiber preform is spun at a forward spinning speed within the range of about 700-3500 meters per minute to produce a partially oriented fiber. The partially oriented fiber is wound without further substantial orientation of the fiber at a draw ratio of less than 1.5. By operating at a forward spinning speed of about 700 meters per minute or more, the partially oriented fiber has a greater tenacity than would be observed for a fiber formed from a corresponding spun isotactic polypropylene. The fiber preform is spun at a forward spinning speed of at least 100 meters per minute to provide a tenacity on the order of about 2 grams per denier or more. The fiber preform may be spun at a forward spinning speed of at least 1500 meters per minute to provide a tenacity of about 3 grams per denier.Type: ApplicationFiled: March 28, 2002Publication date: October 2, 2003Inventors: Mohan Gownder, Jay Nguyen
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Patent number: 6565970Abstract: The present invention relates to a method for the production of polypropylene fibers resulting in improved shrinkage percentages and to polypropylene fibers themselves having improved shrinkage percentages. The method includes providing a polypropylene polymer with a melt flow index of no more than about 25 grams per 10 minutes. This polymer should include isotactic polypropylene produced by the polymerization of propylene in the presence of an isospecific metallocene catalyst. The polymer is then heated to a molten state and extruded to form a fiber preform. The preform is spun and subsequently drawn at a take-away speed and a drawing speed providing a draw ratio of no more than about 3, and more preferably no more than about 2.5, to produce a continuous polypropylene fiber.Type: GrantFiled: October 22, 2001Date of Patent: May 20, 2003Assignee: Fina Technology, Inc.Inventors: Mohan Gownder, Jay Nguyen