Abstract: Gene mutations are associated with the progression of acute myeloid leukemia (AML). The invention relates to methods and systems for evaluating the progression of AML based on these gene mutations. The present invention also relates to methods and compositions for treating AML patients by modulating the expression or activity of certain genes involved in AML progression and/or their encoded proteins. The invention further relates to methods and compositions for determining the responsiveness of an AML patient to induction chemotherapy therapy.

Abstract: A high performance graphics applications controller having a core processor and a coprocessor to independently perform desired graphics functions is provided. The core processor and the coprocessor divides processing tasks to speed execution and to reduce the burden on the host CPU. A direct memory access (DMA) controller cooperates with the coprocessor to generate source and destination addresses and employs a unique set of commands to speed operation. The core processor employs a local CPU and data and address catches to locally perform desired graphics operations independently but in conjunction with the coprocessor. The present invention has particular application with smart terminals and wherever pixel oriented data is required.