Abstract: Generally, the described techniques provide for efficiently transmitting uplink signals to a base station using shared antennas associated with different power classes. A first device may be in communications with a base station using local antennas and may identify a second device having auxiliary antennas available for transmitting uplink signals to the base station. The local and auxiliary antennas may be associated with different power classes, and the first device may transmit a message to a base station indicating that the first device is capable of transmitting using antennas associated with different power classes. The first device may then receive configurations from a base station of different transmit powers to transmit on the antennas associated with the different power classes, and the first device may transmit uplink signals to the base station in accordance with the different transmit power configurations.

Abstract: Disclosed are sweetened consumables and methods of forming said sweetened consumables that comprise certain sweeteners and a compound of formula (1), wherein R1 is selected from the group consisting of OH and OCH3, and R2 is selected from the group consisting of H and OH, R1 and R2 comprise at least one OH group, and when R1 is OH then R2 is H (trilobatin), and when R1 is OCH3 then R2 is OH (HDG), in a concentration near its sweetness detection threshold. The sweeteners include sucrose, fructose, glucose, high fructose corn syrup, corn syrup, xylose, arabinose, rhamnose, erythritol, xylitol, mannitol, sorbitol, inositol, acesulfame potassium, aspartame, neotame, sucralose, saccharine, or combinations thereof.

Abstract: A wellhead housing of a wellhead assembly can include a body having a top end, a bottom end, and a cavity that traverses its length between the top end and the bottom end. The wellhead housing can also include a main channel that traverses the body from the cavity at a distal end of the main channel to an outer perimeter of the body at a proximal end of the main channel, where the proximal end of the main channel is located closer to the top end of the body compared to the distal end of the main channel, and where the distal end of the main channel is located closer to the bottom end of the body compared to the proximal end of the main channel.

Abstract: A tubing spool of a wellhead assembly can include a body having a body cavity, a first channel, and a second channel disposed therein, where the body cavity is configured to receive a tubing hanger used to couple to and suspend a tubing string, where the first channel is configured to be in communication with a tubing string cavity within the tubing string, where the second channel is configured to be in communication with an annulus located between the tubing string and a production casing, and where the first channel and the second channel are each configured to facilitate flow of at least one of a plurality of fluids in either direction independently of each other. The tubing spool can also include a first back pressure valve disposed within the first channel and a second back pressure valve disposed within the second channel.

Abstract: Disclosed herein are compounds that are Hematopoietic Progenitor Kinase 1 (HPK1) inhibitors having a structure according to Formula I, and compositions containing those compounds. Methods of preparing the compounds, and methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.

Abstract: The disclosure relates to macrocyclic peptides and pharmaceutical compositions thereof. The disclosure further relates to pharmaceutical compositions for modulating opioid receptor activity. The macrocyclic tetrapeptides provided herein are useful in treating diseases or disorders relating to the activity of one or more opioid receptors, such as neurological disorders.

Abstract: A wellhead bracing system for a subsea well includes a base plate assembly and a wellhead brace assembly. The base plate assembly comprises a top surface, a bottom surface, a base plate aperture, and a plurality of anchor holes. The wellhead brace assembly comprises a vertical plate assembly having a cylindrical shape, a horizontal plate assembly to which the vertical plate assembly is attached, and a vertical support assembly attached to an outer surface of the vertical plate assembly and attached to the top surface of the horizontal plate assembly. Horizontal plate holes of the horizontal plate assembly are configured to attach to studs on the top surface of the base plate to secure the wellhead brace assembly to the base plate assembly. The wellhead bracing system slides onto a wellhead of the subsea well and braces an exterior of the wellhead.

Abstract: A tubing hanger retention system for a wellhead assembly can include a retention ring that is configured to fit over a top portion of a tubing hanger of the wellhead assembly, where the retention ring comprises a plurality of retention ring channels. The tubing hanger retention system can also include multiple retention pin receiving features configured to be disposed, at least in part, within multiple tubing spool channels of a tubing spool. The tubing hanger retention system can further include multiple retention pins configured to be received by the retention pin receiving features, where each retention pin includes an engagement feature configured to be received by a retention pin receiving feature to place the retention pin in a captured state, where the engagement feature of each retention pin is further configured to enter into an engaged state with a retention ring channel when the retention pin is moved inward.

Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Abstract: Compounds, such as compounds having Formula (I): wherein each variable is as described herein, that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.

Abstract: The present invention is directed towards a window sill flashing comprising a base having a substantially rectangular shape. A front flange projects perpendicularly downward from a front edge of the base and at least one side flange extends vertically from a side edge of the base. The side flange includes a front surface. The window sill flashing is made from a rigid homopolymer vinyl film.

Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.

Abstract: Compounds of Formula I that inhibit AXL, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer, that are mediated, at least in part, by AXL.

Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.

Abstract: A missile for a hydraulic fracturing system can include a high-pressure (HP) missile manifold having a plurality of HP input channels, a HP output channel, and a main HP channel disposed between the plurality of HP input channels and the HP output channel, where each of the plurality of HP input channels is configured to couple to and receive a fracturing fluid from a pump truck, where the HP output channel is configured to couple to and send the fracturing fluid to a main manifold, and where the main HP channel has a widening section along its length that separates a first HP portion of the main HP channel having a first HP diameter and a second HP portion of the main HP channel having a second HP diameter.

Abstract: Compounds that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.

Abstract: The present disclosure is directed to compounds that are inhibitors of HIF-2? having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.

Abstract: A system for fracturing multiple wellbores on a multi-well pad can include a missile that receives high-pressure fracturing fluid from a plurality of pump truck. The system can also include a main manifold that receives the high-pressure fracturing fluid from the missile, where the main manifold includes multiple valves and multiple output channels, where each of the valves are operated between an open position and a closed position. The system can further include multiple wellbores including a first wellbore, a second wellbore, and a third wellbore, where the wellbores are connected to the output channels of the main manifold. The valves of the main manifold can be operated to enable simultaneous flow of the high-pressure fracturing fluid to the first wellbore, the second wellbore, and the third wellbore so that the first wellbore, the second wellbore, and the third wellbore are fractured simultaneously.

Abstract: Oral formulations comprising a compound of Formula (I) and a chelating agent are provided, wherein compounds of Formula (I) have the structure: wherein, W, X, Y, Z, Ra, Rc, and each Rg are as defined herein. Also provided are methods of preparation, methods of use, and specific dosage forms.

Abstract: A sleeve for protecting a lockdown screw of a wellhead assembly can include a body having an inner surface and an outer surface, wherein the body has a concave curvature, where the body is configured to be disposed within an upper portion of a recess of a component of the wellhead assembly inside of which the lockdown screw is disposed, where the concave curvature of the body is configured to match that of an inner wall of the component, and where the outer surface is configured to isolate the lockdown screw from an environment in a cavity partially formed by the inner surface when the body is disposed in the upper portion of the recess.