Abstract: A composition employing a small amount of the hormone melatonin combined with a magnesium compound is formed into a lozenge or into a timed release tablet to act as an antiarrhythmic agent. As a lozenge to be dissolved in the mouth, it may incorporate magnesium in several forms such as a citrate, as a niacinate, as an aspartate, or as an orotate. The preferred formulations according to the invention alleviate cardiac arrhythmia, as well as the extreme manifestation of this condition known as atrial fibrillation. Magnesium citrate is not only beneficial to the heart muscle but also contributes to a laxative effect that counters the constipating action of the melatonin. As a time release tablet for daytime use, the same ingredients indicated above may be combined in tablet or capsular form, but are accompanied by the addition of agents which stimulate the mind such as tyrosine and phenylalanine. These stimulants serve to counter the sleep-inducing action of the melatonin.

Abstract: A composition having therapeutic and cosmetic effects is comprised of an effective concentration of methyl nicotinate in a diluent. When such a composition is topically applied the methyl nicotinate acts to increase circulation in the area of application and also acts as a pain reliever and a muscle relaxant. The composition may also contain various vitamins, minerals and other nutrients. The methyl nicotinate also acts as a facilitator to promote the transdermal penetration of the vitamins, minerals and other nutrients into the skin.