Patents by Inventor Jay Raman

Jay Raman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of human interleukin-4 from a CHO-cell line culture medium
    Patent number: 5034133
    Abstract: Active recombinant human IL-4 is purified from a crude cell culture medium of a CHO-cell lines mutant by subjecting said crude solution to two sequentialcation exchange chromatographies at pH 7.2 and 0.12M sodium chloride, selective chromatography on a cobalt-chelating agarose column at pH 7.2 in a buffer containing a high concentration of sodium chloride, i.e., about 0.5M sodium chloride, further treated by concentration (diafiltration) up to 20 mg/mL and size exclusion gel chromatography using a citrate buffer at pH 4.5.
    Type: Grant
    Filed: July 26, 1990
    Date of Patent: July 23, 1991
    Assignee: Schering-Corporation
    Inventors: David Naveh, Jay Raman, John C. T. Tang