Abstract: A method and system are provided for tracking ST shift data. The system includes an implantable medical device having an input configured to receive cardiac signals. Each cardiac signal has an associated heart rate and includes a segment of interest. The implantable medical device further includes a processor configured to determine segment variations of the segment of interest in the cardiac signals. The processor determines a heart rate associated with each of the segment variations with each heart rate falling within a corresponding heart rate range. The implantable medical device also includes a memory configured to store a group of histograms for a corresponding group of heart rate ranges. The histograms store distributions for the segment variations within corresponding heart rate ranges.

Abstract: Exemplary systems, devices, and methods pertaining to cardiac related therapy and particularly to interferential cardiac preconditioning and depolarization are described. A cardiac arrhythmia is detected from electrogram data sensed from a patient's heart and a region of the heart affected by the cardiac arrhythmia is determined. The affected region is the interferentially energized by multiple cycles of two concurrently delivered alternating currents which are offset in frequency.

Abstract: An exemplary method includes receiving a signal from an intrathoracic vibration sensor, analyzing the signal for vibration associated with deceleration of blood flow into the left ventricle, based at least in part on the analyzing, deciding whether to call for adjustment to one or more parameters of a bi-ventricular pacing therapy. Other exemplary methods, devices, systems, etc., are also disclosed.

Abstract: A method and apparatus for analyzing IEGM waveforms is disclosed. The method includes generating a long term ensemble average of a plurality of baseline IEGM waveforms and generating a short term ensemble average of at least a portion of the plurality of baseline IEGM waveforms. The method further includes determining a short term absolute point value as a function of the absolute value of the difference of the amplitude of the short term ensemble average and a test IEGM waveform and a long term absolute point value as a function of the difference of the amplitude of the long term ensemble average and the test waveform at a plurality of sample points. The disclosed method further includes detecting ischemia if the difference between the short term absolute point value and the long term absolute point value is greater than an ischemia detection threshold.