Patents by Inventor Jay Wohlgemuth

Jay Wohlgemuth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7645575
    Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: January 12, 2010
    Assignee: XDX, Inc.
    Inventors: Jay Wohlgemuth, Darren Tayama, Dirk Walther, Preeti G. Lal
  • Publication number: 20090263800
    Abstract: Methods of diagnosing or monitoring transplant rejection or cytomegalovirus infection in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection or cytomegalovirus infection and kits or systems containing the same are also described.
    Type: Application
    Filed: December 5, 2008
    Publication date: October 22, 2009
    Applicant: XDx, INC.
    Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20090263796
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Application
    Filed: September 23, 2008
    Publication date: October 22, 2009
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Patent number: 7604936
    Abstract: Methods of diagnosing or monitoring auto immune and chronic inflammatory diseases, particularly systemic lupus erythematosis and rheumatoid arthritis, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring auto immune and chronic inflammatory diseases, particularly systemic lupus erythematosis and rheumatoid arthritis and kits or systems containing the same are also described.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: October 20, 2009
    Assignee: XDX, Inc.
    Inventors: Jay Wohlgemuth, Kirk E. Fry, Robert Woodward, Ngoc Ly
  • Patent number: 7579148
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: August 25, 2009
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20080199853
    Abstract: Methods of diagnosing or monitoring auto immune and chronic inflammatory diseases, particularly systemic lupus erythematosis and rheumatoid arthritis, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring auto immune and chronic inflammatory diseases, particularly systemic lupus erythematosis and rheumatoid arthritis and kits or systems containing the same are also described.
    Type: Application
    Filed: April 24, 2003
    Publication date: August 21, 2008
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Patent number: 7235358
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: June 26, 2007
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
  • Publication number: 20070037166
    Abstract: Methods of diagnosing or monitoring transplant rejection or cytomegalovirus infection in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection or cytomegalovirus infection and kits or systems containing the same are also described.
    Type: Application
    Filed: November 15, 2004
    Publication date: February 15, 2007
    Applicant: EXPRESSION DIAGNOSTICS, INC.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20070037167
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Application
    Filed: November 15, 2004
    Publication date: February 15, 2007
    Applicant: EXPRESSION DIAGNOSTICS, INC.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20070037144
    Abstract: Leukocyte gene expression profiling is utilized to identify oligonucleotides from gene expression candidate libraries. The expression libraries are generally immobilized on an array. Diagnostic oligonucleotide sets for analysis of leukocyte-related diseases are described.
    Type: Application
    Filed: October 22, 2001
    Publication date: February 15, 2007
    Inventors: Jay Wohlgemuth, Kirk Fry, George Matcuk, Peter Altman, James Prentice, Julie Phillips, Ngoc Ly, Robert Woodward, Thomas Quertermous, Frances Johnson
  • Publication number: 20070031890
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: December 20, 2002
    Publication date: February 8, 2007
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
  • Publication number: 20060088836
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: April 24, 2003
    Publication date: April 27, 2006
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Patent number: 7026121
    Abstract: Methods of diagnosing or monitoring transplant rejection or cytomegalovirus infection in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection or cytomegalovirus infection and kits or systems containing the same are also described.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 11, 2006
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20060051803
    Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment reginmen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.
    Type: Application
    Filed: September 8, 2005
    Publication date: March 9, 2006
    Applicant: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Darren Tayama, Dirk Walther, Preeti Lal
  • Patent number: 6905827
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: June 14, 2005
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20040009479
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Application
    Filed: April 24, 2002
    Publication date: January 15, 2004
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly