Patents by Inventor Jayakrishna Ambati

Jayakrishna Ambati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VEGF-A as an inhibitor of angiogenesis and methods of using same
    Publication number: 20060135423
    Abstract: The invention relates to methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization associated with neovascular disease. Administration of vascular endothelial growth factor (VEGF)-A into the eye when macrophage infiltration is reduced inhibits ocular angiogenesis.
    Type: Application
    Filed: December 21, 2004
    Publication date: June 22, 2006
    Inventor: Jayakrishna Ambati
  • Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration
    Publication number: 20060067935
    Abstract: Activated C3 (C3a) and its receptor (C3aR) and activated C5 (C5a) and its receptor (C5aR) have been shown to induce vascular endothelial growth factor (VEGF) expression in vitro and in vivo. Compositions and methods for inhibiting C3a, C3aR, C5a and C5aR for the treatment and/or prevention of neovascular disease are provided. Also provided are Novel therapeutic targets and diagnostic markers for choroidal neovascularization.
    Type: Application
    Filed: August 9, 2005
    Publication date: March 30, 2006
    Inventor: Jayakrishna Ambati