Patents by Inventor Jaydeep Bhattacharyya
Jaydeep Bhattacharyya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250253017Abstract: A method for determining trial designs that includes obtaining simulation data for a set of trial designs that includes combinations of design options for a set of criteria. The simulation data includes performance parameters and performance parameter values associated with each design in the set of trial designs for the set of criteria. The method further includes determining an optimality criteria for evaluating the trial designs. The optimality criteria includes at least one of Pareto optimality or convex hull optimality for clinical trial design performance values. The method further includes: determining at least one of a cooling cycle, a parameter change, or a direction; and searching, within the set of trial designs, for a set of globally optimum designs based on the optimality criteria using simulated annealing. The simulated annealing is based at least in part on at least one of the cooling cycle, the parameter change, or the direction.Type: ApplicationFiled: March 18, 2025Publication date: August 7, 2025Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12322479Abstract: A method for determining trial designs is provided. The method includes obtaining simulation data for a set of trial designs. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria; determining an optimality criteria for evaluating the trial designs; searching, within the set of trial designs, for globally optimum designs based on the optimality criteria; and recommending globally optimum designs.Type: GrantFiled: January 30, 2021Date of Patent: June 3, 2025Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12211593Abstract: A method, according to some implementations, includes obtaining trial design simulation results for a set of trial designs and determining a set of Pareto designs in the set of trial designs based at least in part on the trial design simulation results and one or more performance parameters. The method further includes determining a set of convex hull designs in the set of trial designs, determining a set of recommended designs based at least in part on the set of Pareto designs and the set of convex hull designs, and transmitting the set of recommended designs.Type: GrantFiled: January 30, 2021Date of Patent: January 28, 2025Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20250022551Abstract: A method for searching clinical trial designs that includes: determining a first convex hull set from a first set of clinical trial designs for a first scenario; simulating the first convex hull set for a second scenario to determine first simulation results; removing the first convex hull set from the first set of clinical trial designs to generate a second set of clinical trial designs; determining a second convex hull set from the second set of clinical trial designs for the first scenario; simulating the second convex hull set for the second scenario to determine second simulation results; determining, based at least in part on the first simulation results and the second simulation results, a refined scenario convex hull set of clinical trial designs for the second scenario from the first convex hull set and the second convex hull set; and transmitting the refined scenario convex hull set.Type: ApplicationFiled: September 27, 2024Publication date: January 16, 2025Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20240404657Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.Type: ApplicationFiled: June 6, 2024Publication date: December 5, 2024Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12051488Abstract: A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.Type: GrantFiled: January 30, 2021Date of Patent: July 30, 2024Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12040059Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.Type: GrantFiled: January 30, 2021Date of Patent: July 16, 2024Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20220382935Abstract: A method, according to some implementations, receiving, for each trial design of a set of trial designs, a simulated performance and presenting, for at least two criteria, a plot of the simulated performance. The method may further include presenting, for at least one additional criteria, a plurality of contour lines on the plot and selecting a subset of the set of trial designs based on the plurality of contour lines.Type: ApplicationFiled: June 22, 2022Publication date: December 1, 2022Inventors: Nitin Patel, Jaydeep Bhattacharyya, Albert M. Kim, Yannis Jemiai, Jay Kyle Wathen, Sagar Mehta, Christopher Michael Porayko
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Publication number: 20220375551Abstract: A method and system including identifying, via at least one processor, a user role; configuring, via the at least one processor, an interface for the user role, wherein configuring the interface includes determining an interface view for the user role; and displaying, via the at least one processor, the interface with the interface view.Type: ApplicationFiled: June 22, 2022Publication date: November 24, 2022Inventors: Nitin Patel, Jaydeep Bhattacharyya, Albert M. Kim, Yannis Jemiai, Jay Kyle Wathen, Sagar Mehta, Christopher Michael Porayko
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Publication number: 20220374558Abstract: A method for trial design analysis that includes receiving, for each trial design of a plurality of trial designs, a set of simulated performance criteria for a set of trial designs, and visualizing, on a graph, values for a first simulated performance criteria and a second simulated performance criteria from the set of simulated performance criteria for each trial design using a location of points on the graph corresponding to the set of trial designs. The method further includes identifying optimal designs based on an optimality criteria using the set of the simulated performance criteria, and determining a tradeoff metric for the first simulated performance criteria and the second simulated performance criteria. The method further includes displaying, the tradeoff metric as a set of lines on the graph, wherein a slope of the lines corresponds to a value of the tradeoff metric.Type: ApplicationFiled: June 22, 2022Publication date: November 24, 2022Inventors: Nitin Patel, Jaydeep Bhattacharyya, Albert M. Kim, Yannis Jemiai, Jay Kyle Wathen, Sagar Mehta, Christopher Michael Porayko
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Publication number: 20210319158Abstract: A method, according to some implementations, includes generating a plurality of base datasets using a random number generator and determining scenario specifications. The method may further include identifying at least one transformation function for at least one of the plurality of base datasets based on the scenario specifications and transforming the at least one of the plurality of base datasets using the at least one transformation function. In some cases, the method may also include generating scenario parameters based on the at least one transformed datasets.Type: ApplicationFiled: June 22, 2021Publication date: October 14, 2021Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri