Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A movable protection and/or rewrapping device for a balloon catheter may include a tubular member with a bore extending along a length thereof. The tubular member may have at least one rib disposed on an inner surface of the bore. The tubular member may be flared away from the bore at one end and inwardly tapered at the other end. The rewrapping device may include an actuator configured to open a longitudinal slit in the tubular member.

Abstract: Medical devices and methods for forming the medical devices are disclosed in the present application. In one illustrative example an occlusion balloon comprises an outer balloon member, and an inner balloon member having an inner wall and an outer wall and extending through at least a portion of the outer balloon member. In at least some examples, when forces acting on the inner wall of the inner balloon member equal forces acting on the outer wall of the inner balloon member, the inner balloon member defines a lumen.

Abstract: Loading tools for use with medical devices are disclosed. An example loading tool may include a tubular sleeve having a proximal end region, a distal end region, and a lumen. The distal end region may be designed to be engaged with a resilient seal member of a hemostasis valve so that a medical device disposed within the lumen can be passed through the resilient seal member. The tubular sleeve may include a tube wall. At least a portion of the tube wall may overlap to define an overlapping region.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: Medical devices and methods for forming the medical devices are disclosed in the present application. In one illustrative example an occlusion balloon comprises an outer balloon member, and an inner balloon member having an inner wall and an outer wall and extending through at least a portion of the outer balloon member. In at least some examples, when forces acting on the inner wall of the inner balloon member equal forces acting on the outer wall of the inner balloon member, the inner balloon member defines a lumen.

Abstract: A drug delivery device that uses centrifugal force to deliver a drug to a body lumen wall. The drug delivery device comprises an impeller that includes an impeller shaft; an impeller head at the distal end of the impeller shaft; a drug lumen; an impeller housing; and a housing shaft attached to the impeller housing. In use, the drug is advanced along the drug lumen to the impeller head; at least the impeller head is rotated so that when drug exits the drug lumen, the centrifugal force of the rotating impeller causes the drug to move radially outward from the drug delivery device, towards and into the body lumen wall.

Abstract: A movable protection and/or rewrapping device for a balloon catheter may include a tubular member with a bore extending along a length thereof. The tubular member may have at least one rib disposed on an inner surface of the bore. The tubular member may be flared away from the bore at one end and inwardly tapered at the other end. The rewrapping device may include an actuator configured to open a longitudinal slit in the tubular member.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A catheter with a fluorescent temperature sensor is shown and described. The catheter includes a lumen, a fiber-optic cable that extends through the lumen. A distal end of the fiber-optic cable is coated with a fluorescent material and a proximal end of the fiber-optic cable is connected to a console. The console includes a light source for transmitting light through the fiber-optic cable for exciting the fluorescent material. The console further includes a photo multiplier tube for converting light emitted by the excited fluorescent material to a plurality of analogue voltage signals. The console further includes a digital oscilloscope linked to the photo multiplier tube for converting the plurality of analogue voltage signals to at least one digital signal. The console further includes a processor linked to the digital oscilloscope for converting the at least one digital signal to a temperature value for the distal end of the fiber-optic cable.

Abstract: An endoprosthesis, such as a stent, includes a ceramic, such as IROX, having a select morphology and composition.

Abstract: Described herein are implantable medical devices, such as intravascular stents, for delivering therapeutic agents to a patient, and methods for making such medical devices. The medical devices comprise a substrate having at least a cavity therein and a pellet disposed in the cavity. The pellet comprises a non-polymeric material having a plurality of pores therein. A therapeutic agent is disposed in at least some of the pores.

Abstract: An endovascular or intraluminal stent comprising an expandable framework including a plurality of interconnected undulating or otherwise connected segments, and a plurality of fibers disposed on the expandable framework. At least a portion of the plurality of fibers is loaded with a therapeutic agent.

Abstract: A method includes: providing a substrate, depositing a ceramic and an extractable material onto the substrate, forming a porous structure in the ceramic by removing the extractable material, and utilizing the ceramic in an endoprosthesis. An endoprosthesis, such as a stent, including a coating formed of a ceramic and an extractable material that can be removed from the coating to form voids is also disclosed.

Abstract: In accordance with an aspect of the invention, implantable or insertable medical devices are provided which comprise a substrate and a therapeutic-agent-loaded porous inorganic fiber.

Abstract: An endoprosthesis, such as a stent, includes a ceramic, such as IROX, having a select morphology and composition.

Abstract: Devices and methods for extracting core material contained in plaque deposits inside a blood vessel are presented. A device in accordance with one embodiment of the invention includes a catheter having an elongate shaft, a collection array of a plurality of collection lumens disposed about the distal portion of the elongate shaft, a means for radially extending and/or collapsing the collection array, and a suction means for extracting material from the lumen of the blood vessel. A method in accordance with one embodiment of the present invention includes the steps of inserting the distal portion of the catheter into a lumen of the blood vessel, positioning the distal end of the collection array proximate plaque deposits, extending the collection array to rupture the plaque deposits and urging core material therefrom, and extracting the material using a suction means fluidly coupled to the proximal end of the collection array.