Patents by Inventor Jaymes Holland

Jaymes Holland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY COMPRISING A PKC INHIBITOR AND A C-MET INHIBITOR
    Publication number: 20240335440
    Abstract: Provided herein is a combination therapy and methods of using such combination therapy to treat diseases or disorders associated with PKC and c-MET.
    Type: Application
    Filed: December 5, 2022
    Publication date: October 10, 2024
    Inventors: Matthew Anthony MAURER, Michael Gabriel O'QUIGLEY, Richard ZANG, Jaymes HOLLAND, Mai Hope LE, Sarah Shwu-Kuan JAW-TSAI
  • COMBINATION THERAPY COMPRISING A PKC INHIBITOR AND A MEK INHIBITOR
    Publication number: 20240207257
    Abstract: Provided herein is a combination therapy and methods of using such combination therapy to treat diseases or disorders associated with PKC and MEK.
    Type: Application
    Filed: April 14, 2022
    Publication date: June 27, 2024
    Inventors: Matthew Anthony MAURER, Michael Gabriel O'QUIGLEY, Jaymes HOLLAND, Sarah Shwu-Kuan Jaw-Tsai, Julie Hambleton, MAI HOPE LE
  • Methods of Using C-Met Modulators
    Publication number: 20230181559
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Application
    Filed: July 26, 2022
    Publication date: June 15, 2023
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • Methods of using c-Met modulators
    Patent number: 11433064
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: September 6, 2022
    Assignee: Exelixis, Inc.
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • Methods of Using C-Met Modulators
    Publication number: 20200330451
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Application
    Filed: July 2, 2020
    Publication date: October 22, 2020
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • Methods of using c-Met modulators
    Patent number: 10736886
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: August 11, 2020
    Assignee: Exelixis, Inc.
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • Methods of Using C-Met Modulators
    Publication number: 20190151302
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • Methods of Using C-Met Modulators
    Publication number: 20160000772
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Application
    Filed: April 29, 2015
    Publication date: January 7, 2016
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • Method of Quantifying Cancer Treatment
    Publication number: 20140330170
    Abstract: This invention is directed to a method for quantifying cancer treatment response in patients with bone metastases using computer aided bone scan assessment, comprising: (a) obtaining a bone scan image; (b) normalizing the obtained bone scan image to identify normalized bone scan lesions; and (c) quantitatively assessing the normalized bone scan lesions using bone scan lesion area, bone scan intensity, or bone scan lesion count.
    Type: Application
    Filed: November 8, 2012
    Publication date: November 6, 2014
    Inventor: Jaymes Holland
  • Methods of Using C-Met Modulators
    Publication number: 20120282179
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Application
    Filed: August 6, 2010
    Publication date: November 8, 2012
    Applicant: Exelixis, Inc.
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland