Patents by Inventor Jayprakash Ajitsingh PARIHAR

Jayprakash Ajitsingh PARIHAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A PROCESS FOR THE PREPARATION OF OZANIMOD AND ITS INTERMEDIATE (S)-l-AMINO-2,3-DIHYDRO-1H-INDENE-4-CARBONITRILE
    Publication number: 20210340115
    Abstract: The present invention relates to an improved process for preparation of Ozanimod (I) or pharmaceutically acceptable salts thereof. The present invention also relates to an improved process for preparation of (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile (II) or its optically active acid salts.
    Type: Application
    Filed: September 12, 2019
    Publication date: November 4, 2021
    Inventors: Kai DONSBACH, Jayprakash Ajitsingh PARIHAR, Sridhar PRATHA, Chinnayya Setty SATYAVARAPU, Leela Kumar NALLURI, Prasad MATTURTI
  • Process for the preparation of brexpiprazole and intermediates thereof
    Patent number: 10358440
    Abstract: The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: July 23, 2019
    Assignee: Cadila Healthcare Limited
    Inventors: Sanjay Jagdish Desai, Jayprakash Ajitsingh Parihar, Alpesh Pravinchandra Shah
  • PROCESSES FOR PREPARATION OF EMPAGLIFLOZIN
    Publication number: 20190202814
    Abstract: The present invention relates to processes for the preparation of empagliflozin. In particular, the present invention relates to the preparation of empagliflozin and intermediates thereof. The present invention also relates to co-crystal of empagliflozin and amino acid and amorphous form of empagliflozin.
    Type: Application
    Filed: March 7, 2019
    Publication date: July 4, 2019
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Mahesh Laljibhai RUPAPARA, Pranav Jitendra GANGWAR, Hardik Bhikhubhai GHODASARA
  • PROCESS FOR THE PREPARATION OF BREXPIPRAZOLE AND INTERMEDIATES THEREOF
    Publication number: 20190177309
    Abstract: The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.
    Type: Application
    Filed: February 13, 2019
    Publication date: June 13, 2019
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Alpesh Pravinchandra SHAH
  • Process for the preparation of dapagliflozin
    Patent number: 9845303
    Abstract: Dapagliflozin compounds and process for dapagliflozin preparation are described. Pharmaceutical compositions comprising dapagliflozin or solvates of dapagliflozin, for the treatment of diabetes are also described.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: December 19, 2017
    Assignee: Cadila Healthcare Limited
    Inventors: Sanjay Jagdish Desai, Jayprakash Ajitsingh Parihar, Mahesh Laljibhai Rupapara
  • Polymorphic forms of ivabradine hydrochloride
    Patent number: 9840469
    Abstract: Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: December 12, 2017
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Mukul Hariprasad Sharma, Piyush Rajendra Sharma, Jayprakash Ajitsingh Parihar
  • PROCESS FOR THE PREPARATION OF BREXPIPRAZOLE AND INTERMEDIATES THEREOF
    Publication number: 20170320862
    Abstract: The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.
    Type: Application
    Filed: May 3, 2017
    Publication date: November 9, 2017
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Alpesh Pravinchandra SHAH
  • PROCESSES FOR THE PREPARATION OF EMPAGLIFLOZIN
    Publication number: 20170247356
    Abstract: The present invention relates to processes for the preparation of empagliflozin. In particular, the present invention relates to the preparation of empagliflozin and intermediates thereof. The present invention also relates to co-crystal of empagliflozin and amino acid and amorphous form of empagliflozin.
    Type: Application
    Filed: August 29, 2016
    Publication date: August 31, 2017
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Mahesh Laljibhai RUPAPARA, Pranav Jitendra GANGWAR, Hardik Bhikhubhai GHODASARA
  • POLYMORPHIC FORMS OF IVABRADINE HYDROCHLORIDE
    Publication number: 20170217898
    Abstract: Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.
    Type: Application
    Filed: April 12, 2017
    Publication date: August 3, 2017
    Inventors: Shriprakash Dhar DWIVEDI, Ashok PRASAD, Mukul Hariprasad SHARMA, Piyush Rajendra SHARMA, Jayprakash Ajitsingh PARIHAR
  • Processes for the preparation of lorcaserin
    Patent number: 9714225
    Abstract: The present invention relates to stable crystalline Form I of lorcaserin hydrochloride of Formula (IA) and processes for its preparation. The invention also relates to processes for the preparation of lorcaserin and pharmaceutically acceptable salts, solvates and hydrates thereof.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: July 25, 2017
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Jayprakash Ajitsingh Parihar, Alpeshkumar Pravinchandra Shah, Samir Rameshbhai Gajjar, Brij Khera
  • PROCESS FOR THE PREPARATION OF DAPAGLIFLOZIN
    Publication number: 20170166547
    Abstract: Dapagliflozin compounds and process for dapagliflozin preparation are described. Pharmaceutical compositions comprising dapagliflozin or solvates of dapagliflozin, for the treatment of diabetes are also described.
    Type: Application
    Filed: October 19, 2016
    Publication date: June 15, 2017
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Mahesh Laljibhai RUPAPARA
  • Polymorphic forms of ivabradine hydrochloride
    Patent number: 9650344
    Abstract: Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: May 16, 2017
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Mukul Hariprasad Sharma, Piyush Rajendra Sharma, Jayprakash Ajitsingh Parihar
  • POLYMORPHIC FORMS OF IVABRADINE HYDROCHLORIDE
    Publication number: 20160318873
    Abstract: Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.
    Type: Application
    Filed: May 31, 2016
    Publication date: November 3, 2016
    Inventors: Shriprakash Dhar DWIVEDI, Ashok PRASAD, Mukul Hariprasad SHARMA, Piyush Rajendra SHARMA, Jayprakash Ajitsingh PARIHAR
  • PROCESSES FOR THE PREPARATION OF LORCASERIN
    Publication number: 20160280658
    Abstract: The present invention relates to stable crystalline Form A of lorcaserin hydrochloride of Formula (IA) and processes for its preparation. The invention also relates to processes for the preparation of lorcaserin and pharmaceutically acceptable salts, solvates and hydrates thereof.
    Type: Application
    Filed: November 13, 2014
    Publication date: September 29, 2016
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Shriprakash Dhar DWIVEDI,, Jayprakash Ajitsingh PARIHAR, Alpeshkumar Pravinchandra SHAH, Samir Rameshbhai GAJJAR, Brij KHERA
  • Polymorphic forms of ivabradine hydrochloride
    Patent number: 9382209
    Abstract: Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: July 5, 2016
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Mukul Hariprasad Sharma, Piyush Rajendra Sharma, Jayprakash Ajitsingh Parihar
  • AMORPHOUS FORM OF CANAGLIFLOZIN AND PROCESS FOR PREPARING THEREOF
    Publication number: 20160083374
    Abstract: The present invention provides invention relates to stable amorphous form of Canagliflozin. The invention also provides the processes for the preparation of an amorphous form of Canagliflozin; and pharmaceutical compositions comprising therapeutically effective amount of an amorphous form of Canagliflozin, use of said composition for treatment of diabetes, obesity and diabetic complications, especially in type-2 diabetes.
    Type: Application
    Filed: May 30, 2014
    Publication date: March 24, 2016
    Inventors: Shriprakash Dhar DWIVEDI, Brij KHERA, Jayprakash Ajitsingh PARIHAR, Jagdish Maganlal PATEL
  • PROCESS FOR THE PREPARATION OF PERAMPANEL
    Publication number: 20160039759
    Abstract: The present invention relates to processes for the preparation of perampanel and its intermediates.
    Type: Application
    Filed: August 3, 2015
    Publication date: February 11, 2016
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh Parihar, Kuldeep Natwarlal Jain, Sachin Ashokrao Patil
  • POLYMORPHIC FORMS OF IVABRADINE HYDROCHLORIDE
    Publication number: 20160024015
    Abstract: Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.
    Type: Application
    Filed: August 4, 2015
    Publication date: January 28, 2016
    Inventors: Shriprakash Dhar DWIVEDI, Ashok Prasad, Mukul Hariprasad Sharma, Piyush Rajendra Sharma, Jayprakash Ajitsingh Parihar
  • PROCESS FOR PREPARATION AND PURIFICATION OF CANAGLIFLOZIN
    Publication number: 20160002275
    Abstract: The present invention provides a canagliflozin complex. The complex is provided with an adsorbent selected from activated carbon, silica gel, ionic or non-ionic polymer and a cyclodextrin or derivatives thereof. The invention also provides a process for the preparation of canagliflozin and its intermediates thereof. The invention further provides a process for the purification of canagliflozin.
    Type: Application
    Filed: June 30, 2015
    Publication date: January 7, 2016
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Jagdish Maganlal PATEL, Uday Suresh SURYAWANSHI, Jaisukh Bhupatbhai BHALALA
  • AMORPHOUS FORM OF DAPAGLIFLOZIN 1,2-PROPANEDIOL
    Publication number: 20150307540
    Abstract: The invention provides an amorphous form of dapagliflozin 1,2-propanediol of Formula (A) or hydrates thereof and their process for preparation. The present invention also provides a pharmaceutical composition comprising art amorphous solid dispersion containing dapagliflozin 1,2-propanediol or hydrates thereof.
    Type: Application
    Filed: February 19, 2015
    Publication date: October 29, 2015
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Shri Prakash Dhar DWIVEDI, Brij KHERA, Jagdish Maganlal PATEL, Sanjay Jagdish DESAI, Jayprakash Ajitsingh PARIHAR, Mahesh Laljibhai RUPAPARA