Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: A battery includes an electrode assembly including a first electrode, second electrode, and a separator between the first electrode and the second electrode, the first electrode including a first region coated with an active material and a second region at a first side and adjacent to the first region, the second region being exposed beyond the separator, and at least part of the second region is an electrode tab; a housing including a first end with a first opening, the housing accommodating the electrode assembly; a first current collector including an edge portion on the electrode assembly, a second region coupling portion extending from the edge portion and coupled with the second region, and a terminal coupling portion spaced apart from the second region coupling portion; and a terminal coupled with the terminal coupling portion.

Abstract: The present disclosure provides a substituted piperidine compound of Chemical Formula 1, or a pharmaceutically acceptable salt thereof having activity of degrading androgen receptor (AR). The present disclosure also provides a composition comprising such a substituted piperidine compound or a pharmaceutically acceptable salt thereof. The present disclosure also provides a medical use of a substituted piperidine compound according to the present disclosure, a salt thereof, and a composition comprising the same for the treatment or prophylaxis of AR-related diseases. The present disclosure also provides a method for treating or preventing an AR-related disease comprising administering to a subject in need thereof an effective amount of a substituted piperidine compound according to the present disclosure, a salt thereof, or a composition comprising the same.

Abstract: A cooling apparatus for a power module including a plurality of cooling modules provided to be in contact with each of both surfaces of the power module, in which the cooling module includes a manifold cover provided with a plurality of guide walls extending in a first direction in a state of being spaced apart from each other and a pin plate having one surface being in contact with the power module and having a plurality of pins extending in a second direction crossing the first direction formed on the other surface thereof.

Abstract: A battery can include an electrode assembly, a battery housing, a terminal and a cap. The electrode assembly can have a first electrode, a second electrode and a separator between the first electrode and the second electrode. Each of the first electrode and the second electrode can have a first portion including an active material corresponding to the separator, and a second portion exposed beyond the separator and not coated with the active material. The battery housing can have a first end with a first opening and a second end with a second opening opposite the first end. The terminal can be electrically connected to the second portion of the first electrode and exposed out of the battery housing through the first opening of the battery housing at the first end.

Abstract: A battery can include an electrode assembly including a first electrode, a second electrode, and a separator between the first electrode and the second electrode. The first electrode can have a pair of first sides and a pair of second sides extending between the pair of first sides, a first portion including an active material extending between the pair of first sides, and a second portion extending between the pair of first sides and exposed beyond the separator along a winding direction. The battery can further include a battery housing having a first opening at a first end and a second end with a second opening opposite the first end, a first current collector including a support portion positioned on the electrode assembly, and a housing cover which seals the first opening.

Abstract: A battery, includes an electrode assembly having a first electrode, a second electrode and a separator, wherein each of the first electrode and the second electrode has a first portion including an active material corresponding to the separator, and a second portion exposed beyond the separator and not coated with the active material; a battery housing having a first end with a first opening and a second end with a second opening opposite the first end, the battery housing accommodating the electrode assembly through the second opening at the second end and electrically connected to the second portion of the second electrode; a terminal electrically connected to the second portion of the first electrode and exposed out of the battery housing through the first opening of the battery housing at the first end; and a cap covering and sealing the second opening at the second end of the battery housing.

Abstract: A battery can include an electrode assembly having a first electrode, a second electrode and a separator. The first electrode can include a first active material region coated with an active material layer along a winding direction and a first uncoated region not coated with the active material layer, and at least part of the first uncoated region used as an electrode tab. The battery can further include a first current collector coupled to at least part of the first uncoated region on the electrode assembly, a battery housing to accommodate the electrode assembly and the first current collector, and an insulator between an inner surface of the battery housing facing the first uncoated region or the first current collector and the first uncoated region or the first current collector to block the electrical connection between the first uncoated region and the battery housing.

Abstract: An electrode assembly includes a first electrode; a second electrode; and a separator, the first electrode, the second electrode, and the separator wound about an axis defining a core and an outer circumference of the electrode assembly. The first electrode has a pair of first sides and a pair of second sides, a first portion extending between the pair of first sides, and a second portion extending between the pair of first sides, the first portion being coated with an active material, and at least a part of the second portion includes an electrode tab. The second portion includes a first part adjacent to the core of the electrode assembly, a second part adjacent to the outer circumference of the electrode assembly, and a third part between the first part and the second part. The first or second part has a smaller height than the third part.

Abstract: The present disclosure provides a substituted piperidine compound of Chemical Formula 1, wherein X is CR3, or a pharmaceutically acceptable salt thereof having activity of degrading androgen receptor (AR). The present disclosure also provides a composition comprising such a substituted piperidine compound or a pharmaceutically acceptable salt thereof. The present disclosure also provides a medical use of a substituted piperidine compound according to the present disclosure, a salt thereof, and a composition comprising the same for the treatment or prophylaxis of AR-related diseases. The present disclosure also provides a method for treating or preventing an AR-related disease comprising administering to a subject in need thereof an effective amount of a substituted piperidine compound according to the present disclosure, a salt thereof, or a composition comprising the same.

Abstract: A battery includes an electrode assembly including a first electrode, second electrode, and a separator between the first electrode and the second electrode, the first electrode including a first region coated with an active material and a second region at a first side and adjacent to the first region, the second region being exposed beyond the separator, and at least part of the second region is an electrode tab; a housing including a first end with a first opening, the housing accommodating the electrode assembly; a first current collector including an edge portion on the electrode assembly, a second region coupling portion extending from the edge portion and coupled with the second region, and a terminal coupling portion spaced apart from the second region coupling portion; and a terminal coupled with the terminal coupling portion.

Abstract: An electrode assembly, a battery, and a battery pack and a vehicle including the same are provided. In the electrode assembly, a first electrode, a second electrode, and a separator interposed therebetween are wound based on an axis to define a core and an outer circumference. The first electrode includes a first portion coated with an active material and a second portion at a first side and adjacent the first portion, the second portion being exposed beyond the separator along a first axial direction of the electrode assembly. A part of the second portion is bent in a radial direction of the electrode assembly forming a first surface region including stacked layers of the second portion, and in a partial region of the first surface region, a number of the stacked layers of the second portion is 10 or more in the in the first axial direction.

Abstract: In the electrode assembly, the first uncoated portion provided at a long side end of a first electrode includes a segment region divided into a plurality of independently bendable segments by a plurality of cut grooves provided along a winding direction. The segment region includes a plurality of segment groups disposed with a group separation pitch along the winding direction. The plurality of segment groups constitute at least one segment alignment on one side of the electrode assembly. At least some of central points of winding turn arcs where the p number of segment groups are located are not located on a predetermined alignment line extending in the radial direction from the center of the core.

Abstract: An electrode assembly, a battery, a battery pack and a vehicle including the same are provided. In the electrode assembly, the uncoated portion of an electrode includes a segment region divided into a plurality of segments, and the segment region includes a plurality of segment groups separated by a group separation pitch along a winding direction. One end of the electrode assembly includes a plurality of segment alignments. In winding turns corresponding to the plurality of segment alignments, group separation pitches of segment groups disposed in a same winding turn are substantially identical, and separation pitches of the segment groups is greater in a winding turn of a region adjacent to the outer circumference of the electrode assembly than in a winding turn of a region adjacent to the core of the electrode assembly.

Abstract: Disclosed is a fixing structure of an electrode terminal, and a battery, a battery pack and a vehicle including the same. The fixing structure of an electrode terminal includes a battery housing configured to be opened at one side and have a bottom at the other side in which a perforation hole is formed; an electrode terminal installed through the perforation hole not to contact an inner wall of the perforation hole; and a terminal gasket interposed between the electrode terminal and the perforation hole, and the electrode terminal includes a body portion inserted into the perforation hole; an outer flange portion configured to extend along an outer surface of the bottom of the battery housing from a first side of the body portion; an inner flange portion configured to extend toward an inner surface of the bottom of the battery housing from a second side of the body portion; and a flat portion provided to an inner side of the inner flange portion.

Abstract: Discussed is a battery including an electrode assembly having a first electrode, a second electrode and a separator wound about an axis, and each of the first electrode and the second electrode has a first portion including an active material corresponding to the separator, and a second portion exposed beyond the separator and not coated with the active material, a housing having a first end with a first opening and a second end with a second opening opposite the first end, the housing accommodating the electrode assembly, a terminal electrically connected to the second portion of the first electrode and exposed out of the housing through the first opening of the housing at the first end, a cap at the second end of the housing, and an insulating gasket having an extended shape to cover the outer circumferential surface of the terminal.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: An electrode assembly, a battery, a battery pack and a vehicle including the same are provided. The first electrode of the electrode assembly includes a first active material portion coated with an active material layer and a first uncoated portion not coated with an active material layer along a winding direction, the first uncoated portion includes a plurality of segments independently bendable along the winding direction and exposed beyond a the separator of the electrode assembly, the plurality of segments are aligned along a radial direction of the electrode assembly to define a plurality of segment alignments spaced apart in a circumferential direction of the electrode assembly, and an electrolyte impregnation portion in which an end of the first active material portion is exposed between winding turns of the separator is included between adjacent segment alignments of the first uncoated portion in the circumferential direction.

Abstract: An electrode assembly, a battery, and a battery pack and a vehicle including the same are provided. One end of the electrode assembly includes a plurality of segment alignments in which the plurality of segment groups are aligned along a radial direction, and an electrolyte impregnation portion provided between segment alignments adjacent in a circumferential direction, wherein an end of the first active material portion is exposed between winding turns of the separator. The segments included in the segment alignment are bent toward the core to form a bending surface region. An end of the separator is spaced apart from a criterion line extending in a winding axis direction along a location corresponding to the plurality of cut grooves by 30% or less of a minimum height of the segments forming the bending surface region.

Abstract: Discussed is a battery including an electrode assembly having a first electrode, a second electrode and a separator between the first electrode and the second electrode, a battery housing having a first end with a first opening and a second end with a second opening opposite the first end, the battery housing accommodating the electrode assembly and electrically connected to the second electrode to have a second polarity, a terminal electrically connected to the first electrode to have a first polarity, the terminal being exposed out of the battery housing through the first opening of the battery housing at the first end, and a cap covering and sealing the second opening at the second end of the battery housing. The cap overlaps the battery housing at the second end and has no polarity.