Abstract: The present invention provides Streptomyces coelicolor strain A3(2)_M22-2C43 obtained by inducing a point mutation in the base sequence of the DagB gene in a wild-type Streptomyces coelicolor strain A3(2) by UV radiation. Since the Streptomyces coelicolor strain A3(2)_M22-2C43 according to the present invention expresses a DagB mutant enzyme expressing little or no DagB beta-agarase or exhibiting little or no beta-agarase activity, there is no need for separate isolation and purification of DagA enzymes from culture fluid, and the culture fluid of the Streptomyces coelicolor strain A3(2)_M22-2C43 or supernatant thereof may be used to produce, from agar or agarose, neoagarose oligosaccharides with a higher content of neoagarotetraose or neoagarohexaose than that of neoagarobiose.

Abstract: The disclosure relates to a sensor network, machine type communication (MTC), machine-to-machine (M2M) communication, and technology for internet of things (IoT). A method of a server is provided. The method includes determining a target temperature range to be applied to a first zone; predicting an indoor temperature for each of a plurality of zones included in a second zone in which the first zone is included; predicting efficiency of at least one first outdoor unit connected to first indoor units installed at the second zone; and controlling operations of the first indoor units based on the target temperature range, the indoor temperature for each of the plurality of zones, and the efficiency of at least one first outdoor unit.

Abstract: An air conditioner and a control method for the same, the air conditioner including an air conditioning unit including a compressor, a first heat exchanger, an expansion valve, and a second heat exchanger; and a controller configured to obtain enthalpy of a refrigerant flowing in the air conditioning unit, obtain an air conditioning capacity using a circulation amount of the refrigerant and the obtained enthalpy of the refrigerant, obtain efficiency based on the obtained air conditioning capacity and supplied power, and control the air conditioning unit according to the obtained efficiency.

Abstract: Provided in the present invention is a novel use of composition containing a neoagarooligosaccharide mixture as an active ingredient. The neoagarooligosaccharide mixture and the like as an active ingredient of the composition according to the present invention can reduce the expression of RANKL, an osteoclast inducer, or IL-6, an inflammatory cytokine, and effectively inhibit differentiation of monocytes into osteoclasts. Thus, the composition according to the present invention may be used as a medicine or functional food for preventing, alleviating, or treating arthritis (especially rheumatoid arthritis). Further, the active ingredient of the composition according to the present invention can be obtained by an enzyme reaction between a readily available substrate such as agar or agarose and DagA as a beta-agarase derived from Streptomyces coelicolor. Thus, it can be produced at a relatively low cost and can easily be ingested by anyone because it has no side effects.

Abstract: The present invention provides Streptomyces coelicolor strain A3(2)_M22-2C43 obtained by inducing a point mutation in the base sequence of the DagB gene in a wild-type Streptomyces coelicolor strain A3(2) by UV radiation. Since the Streptomyces coelicolor strain A3(2)_M22-2C43 according to the present invention expresses a DagB mutant enzyme expressing little or no DagB beta-agarase or exhibiting little or no beta-agarase activity, there is no need for separate isolation and purification of DagA enzymes from culture fluid, and the culture fluid of the Streptomyces coelicolor strain A3(2)_M22-2C43 or supernatant thereof may be used to produce, from agar or agarose, neoagarose oligosaccharides with a higher content of neoagarotetraose or neoagarohexaose than that of neoagarobiose.

Abstract: Disclosed are an air conditioning apparatus and a control method thereof. An air conditioning apparatus comprises: a driving unit for performing a pre-configured function of the air conditioning apparatus; a sensor for collecting environmental information around the air conditioning apparatus; a memory for storing the collected environmental information; and a processor for controlling an operation of the driving unit on the basis of schedule information including an operating state defined according to a time change, and modifying the schedule information on the basis of environmental information collected during a pre-configured period of time.

Abstract: The present invention relates to a composition for prevention or treatment of sepsis or septic shock, in which the composition includes neoagarooligosaccharide as an active ingredient, and the neoagarooligosaccharide according to the present invention has an excellent effect in terms of immune enhancement by effectively suppressing inflammation, and also exhibits a good effect in preventing sepsis, and therefore can be effectively used in pharmaceuticals and functional foods for prevention or treatment of sepsis or septic shock and immune enhancement.

Abstract: The present invention relates to a composition for prevention or treatment of sepsis or septic shock, in which the composition includes neoagarooligosaccharide as an active ingredient, and the neoagarooligosaccharide according to the present invention has an excellent effect in terms of immune enhancement by effectively suppressing inflammation, and also exhibits a good effect in preventing sepsis, and therefore can be effectively used in pharmaceuticals and functional foods for prevention or treatment of sepsis or septic shock and immune enhancement.

Abstract: Provided in the present invention is a composition having a novel use and containing a neoagarooligosaccharide mixture as an active ingredient. According to the present invention, a neoagarooligosaccharide mixture, which is the active ingredient of the composition according to the present invention, and the like can reduce the expression of RANKL, which is an osteoclast inducer, and effectively inhibit the differentiation of mononuclear cells into osteoclasts. Therefore, the composition according to the present invention can be used as a medicine or functional food for preventing, alleviating, or treating arthritis (especially rheumatoid arthritis) or osteoporosis.

Abstract: The disclosure relates to a sensor network, machine type communication (MTC), machine-to-machine (M2M) communication, and technology for internet of things (IoT). A method of a server is provided. The method includes determining a target temperature range to be applied to a first zone; predicting an indoor temperature for each of a plurality of zones included in a second zone in which the first zone is included; predicting efficiency of at least one first outdoor unit connected to first indoor units installed at the second zone; and controlling operations of the first indoor units based on the target temperature range, the indoor temperature for each of the plurality of zones, and the efficiency of at least one first outdoor unit.

Abstract: A method for controlling an air conditioner is provided. The method includes calculating an index weight outdoor average temperature by calculating outdoor temperature data over a predetermined period, acquiring position information in which the air conditioner is installed, selecting an appropriate climatic model according to the position information, calculating a comfortable temperature of the day by substituting the index weight outdoor average temperature to the climatic model, setting the comfortable temperature as an indoor target temperature, and controlling a cooling or a heating of the air conditioner so that the indoor temperature reaches the indoor target temperature.

Abstract: An air conditioner and a control method for the same, the air conditioner including an air conditioning unit including a compressor, a first heat exchanger, an expansion valve, and a second heat exchanger; and a controller configured to obtain enthalpy of a refrigerant flowing in the air conditioning unit, obtain an air conditioning capacity using a circulation amount of the refrigerant and the obtained enthalpy of the refrigerant, obtain efficiency based on the obtained air conditioning capacity and supplied power, and control the air conditioning unit according to the obtained efficiency.

Abstract: The present invention relates to a composition for prevention or treatment of sepsis or septic shock, in which the composition includes neoagarooligosaccharide as an active ingredient, and the neoagarooligosaccharide according to the present invention has an excellent effect in terms of immune enhancement by effectively suppressing inflammation, and also exhibits a good effect in preventing sepsis, and therefore can be effectively used in pharmaceuticals and functional foods for prevention or treatment of sepsis or septic shock and immune enhancement.

Abstract: A method for controlling an air conditioner is provided. The method includes calculating an index weight outdoor average temperature by calculating outdoor temperature data over a predetermined period, acquiring position information in which the air conditioner is installed, selecting an appropriate climatic model according to the position information, calculating a comfortable temperature of the day by substituting the index weight outdoor average temperature to the climatic model, setting the comfortable temperature as an indoor target temperature, and controlling a cooling or a heating of the air conditioner so that the indoor temperature reaches the indoor target temperature.