Patents by Inventor Je-Jung Lee

Je-Jung Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION CONTAINING FEEDER CELL FOR PROLIFERATING NATURAL KILLER CELL
    Publication number: 20240254445
    Abstract: The present invention relates to a composition for proliferating natural killer cells, comprising feeder cells and a method for proliferating natural killer cells. Specifically, the present invention relates to a method for proliferating natural killer cells by using feeder cells that are transformed to express at least one gene selected from the group consisting of B7H6, CD137L, IL-15, and IL-15R?.
    Type: Application
    Filed: May 31, 2022
    Publication date: August 1, 2024
    Inventors: Sang Ki KIM, Joon Haeng RHEE, Je Jung LEE
  • Anticancer composition
    Patent number: 8809297
    Abstract: Disclosed is an anticancer composition, comprising an inhibitor against WIG1 and/or YPEL5 or against a protein encoded by the gene. A composition for screening an anticancer agent comprising a nucleic acid having a sequence complementary to an mRNA of WIG1 and/or YPEL5, or an antibody to a protein encoded by the gene is also provided. Also, a method is provided for screening an anticancer agent, which comprises: (A) quantitatively analyzing expression of WIG1 and/or YPEL5 at an mRNA or protein level in a tumor cell which is not treated with a candidate for an anticancer agent; (B) quantitatively analyzing expression of the gene at an mRNA or protein level in a tumor cell after treatment of the candidate for an anticancer agent; and (C) selecting the candidate if the expression level of the gene is increased in step (B), compared to step (A).
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: August 19, 2014
    Assignee: Korea Institute of Radiological & Medical Sciences
    Inventors: Jae-Seon Lee, Bong Cho Kim, Je-Jung Lee, Su Min Park
  • ANTICANCER COMPOSITION
    Publication number: 20130149319
    Abstract: Disclosed is an anticancer composition, comprising an inhibitor against WIG1 and/or YPEL5 or against a protein encoded by the gene. A composition for screening an anticancer agent comprising a nucleic acid having a sequence complementary to an mRNA of WIG1 and/or YPEL5, or an antibody to a protein encoded by the gene is also provided. Also, a method is provided for screening an anticancer agent, which comprises: (A) quantitatively analyzing expression of WIG1 and/or YPEL5 at an mRNA or protein level in a tumor cell which is not treated with a candidate for an anticancer agent; (B) quantitatively analyzing expression of the gene at an mRNA or protein level in a tumor cell after treatment of the candidate for an anticancer agent; and (C) selecting the candidate if the expression level of the gene is increased in step (B), compared to step (A).
    Type: Application
    Filed: May 28, 2010
    Publication date: June 13, 2013
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jae-Seon Lee, Bong Cho Kim, Je-Jung Lee, Su Min Park