Patents by Inventor Je Sun You

Je Sun You has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Temperature and pH sensitive block copolymer and polymeric hydrogels using the same
    Patent number: 8835492
    Abstract: Disclosed is a block copolymer formed by coupling the following components with each other: (a) a copolymer (A) of a polyethylene glycol (PEG) type compound with a biodegradable polymer; and (b) at least one oligomer (B) selected from the group consisting of poly(?-amino ester) and poly(amido amine). A method for preparing the same block copolymer, and a polymeric hydrogel type drug composition comprising the temperature and pH-sensitive block copolymer and a physiologically active substance that can be encapsulated with the block copolymer are also disclosed. The multiblock copolymer is obtained by copolymerization of a pH-sensitive poly(?-amino ester) and/or poly(amido amine) type oligomer, a hydrophilic and temperature-sensitive polyethylene glycol type compound and a hydrophobic and biodegradable polymer.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: September 16, 2014
    Assignee: Sungyunkwan University Foundation for Corporate Collaboration
    Inventors: Doo Sung Lee, Min Sang Kim, Je Sun You, Huynh Dai Phu, Bong Sup Kim, Minh Khanh Nguyen
  • pH and temperature sensitive hydrogels
    Patent number: 7786220
    Abstract: The present invention relates to a block copolymer formed by coupling the following components with each other, as well as a hydrogel composition comprising the block copolymer and a hydrogel formed from the composition: (a) a copolymer of a polyethylene glycol (PEG)-based compound with a biodegradable polymer; and (b) a sulfonamide-based oligomer. The inventive block copolymer shows the sol-gel transition behavior sensitive to changes in not only temperature but also pH. Thus, the inventive block copolymer overcomes the shortcomings of temperature-sensitive copolymers, form a more strong and stable hydrogel, and is stable in vivo. Accordingly, the inventive block copolymer can be used in various applications in the medical and drug delivery fields.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: August 31, 2010
    Assignee: Sungyunkwan University Foundation for Corporate Collaboration
    Inventors: Doo Sung Lee, Woo Sun Shim, You Han Bae, Je Sun You, Min Sang Kim, Huynh Dai Phu
  • Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same
    Publication number: 20080293827
    Abstract: Disclosed is a block copolymer formed by coupling the following components with each other: (a) a copolymer (A) of a polyethylene glycol (PEG) type compound with a biodegradable polymer; and (b) at least one oligomer (B) selected from the group consisting of poly(?-amino ester) and poly(amido amine). A method for preparing the same block copolymer, and a polymeric hydrogel type drug composition comprising the temperature and pH-sensitive block copolymer and a physiologically active substance that can be encapsulated with the block copolymer are also disclosed. The multiblock copolymer is obtained by copolymerization of a pH-sensitive poly(?-amino ester) and/or poly(amido amine) type oligomer, a hydrophilic and temperature-sensitive polyethylene glycol type compound and a hydrophobic and biodegradable polymer.
    Type: Application
    Filed: March 31, 2006
    Publication date: November 27, 2008
    Applicant: SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR COROPORATE COLLABORATION
    Inventors: Doo Sung Lee, Min Sang Kim, Je Sun You, Huynh Dai Phu, Bong Sup Kim, Minh Khanh Nguyen