Patents by Inventor Jean-Bernard Cazaux

Jean-Bernard Cazaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7999061
    Abstract: A catalytic lactide and glycolide copolymerization system comprising a trifluoromethane sulfonate as a catalyst and copolymerization additive and a copolymerization process.
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: August 16, 2011
    Assignee: IPSEN Pharma S.A.S.
    Inventors: Blanca Martin-Vaca, Anca Dumitrescu, Lidija Vranicar, Jean-Bernard Cazaux, Didier Bourissou, Roland Cherif-Cheikh, Frédéric Lacombe
  • Publication number: 20090171066
    Abstract: A catalytic lactide and glycolide copolymerization system comprising a trifluoromethane sulfonate as a catalyst and copolymerization additive and a copolymerization process.
    Type: Application
    Filed: December 11, 2008
    Publication date: July 2, 2009
    Inventors: Blanca Martin-Vaca, Anca Dumitrescu, Lidija Vranicar, Jean-Bernard Cazaux, Didier Bourissou, Roland Cherif-Cheikh, Frederic Lacombe
  • Patent number: 7169729
    Abstract: The invention concerns the use of zinc derivatives of general formula (I) wherein: L1 represents a group of formula: —E14(R14)(R?14)(R?14), —E15(R15) (R?15) or —E16(R16); E is an atom of group 15; L2 and L3 independently represent a group of formula: —E14(R14)(R?14)(R?14), —E15(R15)(R?15) or —E16(R16), or together form a chain of formula —L?2—A—L?3—; A represents a saturated or unsaturated chain comprising one, two or three elements of group 14; L?2 and L?3 independently represent a group of formula —E14(R14)(R?14) —E15(R15) or —E16—; E14 is an element of group 14; E15 is an element of group 15; E16 is an element of group 16; R14, R?14, R?14, R15, R?15 and R16 represent various groups, as (co) polymerisation catalysts of cyclic esters
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: January 30, 2007
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Anca Dumitrescu, Martin-Vaca Blanca, Heinz Gornitzka, Didier Bourissou, Jean-Bernard Cazaux, Guy Bertrand
  • Patent number: 7135478
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: November 14, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Patent number: 7101959
    Abstract: A subject of the present invention is new compounds having a lanthanide and having a tridentate ligand, a process for their preparation and their use in particular as polymerization catalysts.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: September 5, 2006
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Anca Dumitrescu, Heinz Gornitzka, Blanca Martin-Vaca, Didier Bourissou, Guy Bertrand, Jean-Bernard Cazaux
  • Patent number: 7094862
    Abstract: The invention relates to a method for preparing polyesters A containing several mid-chain free acid functions by ring-opening polymerisation in the presence of a chain initiator: the benzyl diester of the tartaric acid, the phenyl radical of which is optionally substituted. A: aliphatic based on cyclic esters such as lactides and glycolides.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: August 22, 2006
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Jean-Bernard Cazaux, Charles Brigati, Alexandre Louchkoff, Francis Diancourt
  • Patent number: 7084237
    Abstract: The use of stannylenes and germylenes of general formula (I) wherein: M represents a tin or geranium atom; L1 and L2 independently represent a group of formula: -E14(R14) (R?14) (R?14), -E15(R15) (R?15) or -E16(R16)) or together form a chain of formula -L?1-A- L?2; A represents a saturated or unsaturated chain comprising one, two or three elements of group 14; L?1 and L?2, represent, independently, a group of formula: -E14(R14) (R?14)-, E15(R15)- or -E16-; E14 is an element of group 14; E15 is an element of group 15; E16 is an element of group 16; R14, R?14, R?14, R15, R?15 and R16 represent variable groups as polymerization catalysts of heterocycles.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: August 1, 2006
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.), Centre National de la Recherche Scientifique
    Inventors: Anca Dumitrescu, Heinz Gornitzka, Blanca Martin-Vaca, Didier Bourissou, Guy Bertrand, Jean-Bernard Cazaux
  • Publication number: 20060149030
    Abstract: A catalytic lactide and glycolide copolymerization system comprising a trifluoromethane sulfonate as a catalyst and copolymerization additive and a copolymerization process.
    Type: Application
    Filed: January 19, 2004
    Publication date: July 6, 2006
    Inventors: Blanca Martin-Vaca, Anca Dumitrescu, Lidija Vranicar, Jean-Bernard Cazaux, Didier Bourissou, Roland Cherif-Cheikh, Frederic Lacombe
  • Patent number: 7053102
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring ?-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: May 30, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Patent number: 6936733
    Abstract: The invention concerns a novel method for industrial preparation of disodium 2,2?-dithiobis(alkylsulphonates), and in particular disodium 2,2?-dithiobis(ethanesulphate) (dimesna). Said novel method is summarized by the reaction diagram (A). In diagram (A), Hal represents a halogen atom, and preferably a bromine atom; M represents a sodium or potassium atom; and n represents an integer ranging between 0 and 2.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 30, 2005
    Assignee: BioNumerik Pharmaceuticals, Inc.
    Inventors: Jean-Bernard Cazaux, Eric Manginot, Marc Veyrat
  • Publication number: 20050038064
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Application
    Filed: August 31, 2004
    Publication date: February 17, 2005
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Publication number: 20040254163
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring &bgr;-hydroxy lactone ring of the formula 1
    Type: Application
    Filed: June 7, 2004
    Publication date: December 16, 2004
    Applicant: SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Patent number: 6815546
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: November 9, 2004
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Publication number: 20040209768
    Abstract: A subject of the present invention is new compounds having a lanthanide and having a tridentate ligand, a process for their preparation and their use in particular as polymerization catalysts.
    Type: Application
    Filed: January 20, 2004
    Publication date: October 21, 2004
    Inventors: Anca Dumitrescu, Heinz Gornitzka, Blanca Martin-Vaca, Didier Bourissou, Guy Bertrand, Jean-Bernard Cazaux
  • Patent number: 6797715
    Abstract: A method of treating a cancer in warm-blooded animals by administration to the warm-blooded animals in need thereof a camptothecin analog a 7-ring member &bgr;-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: September 28, 2004
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Patent number: 6790972
    Abstract: The invention relates to new compounds having an element of group 12 and having a tridentate ligand, a process for their preparation and their use in particular as a polymerization catalyst.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: September 14, 2004
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Hanh Nguyen Ngoc, Heinz Gornitzka, Blanca Martin-Vaca, Didier Bourissou, Guy Bertrand, Jean-Bernard Cazaux
  • Patent number: 6762301
    Abstract: A process for the preparation of a compound of the formula wherein the substituents are defined as set forth in the specification comprising reacting a compound of the formula with a 2-halo-3-quinoline-methanol of the formula to obtain a compound of the formula which is then cyclized to form the compound of Formula I.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: July 13, 2004
    Assignee: Societe de Conseils de Recherches et Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Publication number: 20040127676
    Abstract: The invention relates to a method for preparing polyesters A containing several mid-chain free acid functions by ring-opening polymerisation in the presence of a chain initiator: the benzyl diester of the tartaric acid, the phenyl radical of which is optionally substituted. A: aliphatic based on cyclic esters such as lactides and glycolides.
    Type: Application
    Filed: December 1, 2003
    Publication date: July 1, 2004
    Inventors: Jean-Bernard Cazaux, Charles Brigati, Alexandre Louchoff
  • Publication number: 20040110912
    Abstract: The invention concerns the use of zinc derivatives of general formula (I) wherein: L1 represents a group of formula: —E14(R′14)(R″14), —E15(R15)(R′15) or —E16(R16); E is an atom of group 15; L2 and L3 independently represent a group of formula: —E14(R14)(R′14)(R″14), —E15(R15)(R′15) or —E16(R16), or together form a chain of formula —L′2—A—L′3—; A represents a saturated or unsaturated chain comprising one, two or three elements of group 14; L′2 and L′3 independently represent a group of formula —E14(R14)(R′14) —E15(R15) or —E16—; E14 is an element of group 14; E15 is an element of group 15; E16 is an element of group 16; R14, R′14, R″1, R15, R′15 and R16 represent various groups, as (co) polymerisation catalysts of cyclic esters.
    Type: Application
    Filed: November 3, 2003
    Publication date: June 10, 2004
    Inventors: Anca Dumitrescu, Martin-Vaca Blanca, Heinz Gornitzka, Didier Bourissou, Jean-Bernard Cazaux, Guy Bertrand
  • Patent number: 6716787
    Abstract: A subject of the present invention is new compounds having a lanthanide and having a tridentate ligand, a process for their preparation and their use in particular as polymerization catalysts.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: April 6, 2004
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Anca Dumitrescu, Heinz Gornitzka, Blanca Martin-Vaca, Didier Bourissou, Guy Bertrand, Jean-Bernard Cazaux