Abstract: The present invention is directed to a process for making (2S,5S)-5-fluoromethylornithine through the reaction of wet penicillin acylase with (2R,5R) and (2S,5S)-6-fluoromethyl-3-(phenylactyl)-amino-2-piperidone and the addition of an acid to the resulting product.

Abstract: This invention relates to novel N-derivatives of 1-deoxy nojirimycin, to the method for their preparation and to their use in the treatment of diabetes and the use against retro-viruses, particularly in the treatment of acquired immuno-deficiency syndrome (AIDS).

Abstract: This invention relates to novel polyglycosidyl derivatives of 1-deoxy-nojirimycin, to the processes for their preparation and to their end-use applications, particularly as to their use in the treatment of diabetes.

Abstract: This invention relates to novel N-derivatives of 1-deoxy nojirimycin, to the method for their preparation and to their use in the treatment of diabetes and the use against retro-viruses, particularly in the treatment of acquired immuno-deficiency syndrome (AIDS).

Abstract: Fluorinated arachidonic derivatives are 5-lipoxygenase inhibitors which have the useful pharmacologic activity as antiallergy and anti-inflammatory agents and are useful for treating, for example, asthma, anaphylaxis, allergy, rheumatoid arthritis, and psoriasis and cardiovascular diseases.

Abstract: This invention relates to novel N-derivatives of 1-deoxy-nojirimycin, to the processes for their preparation and to their end-use applications, particularly as to their use in the treatment of diabetes.

Abstract: This invention relates to novel N-glycosyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol, to the chemical processes for their preparation, to their .alpha.-glucosidase inhibiting properties, and to their end-use application in the treatment of diabetes, obesity and those diseases associated with retroviruses, particularly the HIV virus reported to be the causative of the acquired immune deficiency syndrome (AIDS).

Abstract: Daunorubicin derivatives of the formula: ##STR1## wherein R.sub.1 represents a group of the formula: ##STR2## in which (i) X.sub.1 and X.sub.2 both represent oxygen or both represent sulphur and the symbols R.sub.3 each represent alkyl of 1 through 4 carbon atoms, phenyl or phenyl substituted in the para-position by methyl, methoxy or methylthio, or together form an alkylene radical of 2 through 4 carbon atoms, or (ii) one of X.sub.1 and X.sub.2 represents oxygen and the other represents sulphur and the symbols R.sub.3 together form an alkylene radical of 2 through 4 carbon atoms, and R.sub.4 represents hydrogen, alkyl of 1 through 4 carbon atoms or phenyl, and R.sub.2 represents hydrogen or trifluoroacetyl, are new compounds possessing anti-tumour properties.

Abstract: Daunorubicin derivatives of the general formula: ##STR1## wherein each of the symbols R represents a hydrogen atom or a methyl or ethyl radical, are new therapeutically useful compounds possessing anti-tumoral properties.

Abstract: The new naphthacene derivatives of the general formula: ##STR1## wherein A represents a single bond or a methylene group and acid addition salts thereof possess valuable anti-tumor properties. They are prepared by reaction of an acid addition salt of a strong acid of a corresponding naphthacene derivative having a ##STR2## group in the 13-position with a compound of the formula HO--CH.sub.2 --A--CH.sub.2 --OH.