Patents by Inventor Jean C.Y. Wang

Jean C.Y. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING HEMATOLOGICAL CANCERS TARGETING THE SIRPALPHA - CD47 INTERACTION
    Publication number: 20240084399
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Applicants: UNIVERSITY HEALTH NETWORK, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Jean C.Y. WANG, John DICK, Jayne DANSKA, Liqing JIN, Alexandre THEOCHARIDES, Sujeetha RAJAKUMAR
  • METHOD FOR IDENTIFYING HIGH-RISK AML PATIENTS
    Publication number: 20210371937
    Abstract: There is described herein an assay comprising, for each of DNMT3B, ZBTB46, NYNRIN, ARHGAP22, LAPTM4B, MMRN1, DPYSL3, KIAA0125, CDK6, CPXM1, SOCS2, SMIM24, EMP1, NGFRAP1, CD34, AKR1C3, GPR56, a pair of probes complementary and hybridizable thereto on an array, optionally with a set of reference genes.
    Type: Application
    Filed: August 5, 2021
    Publication date: December 2, 2021
    Inventors: JEAN C.Y. WANG, ZHIBIN LU, STANLEY NG, TRACY STOCKLEY, TRACY MURPHY, IAN KING, TONG ZHANG, MICHELLE MAH
  • Compositions and methods for treating hematological cancers targeting the SIRP? CD47 interaction
    Patent number: 10907209
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: February 2, 2021
    Assignees: UNIVERSITY HEALTH NETWORK, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Jean C. Y. Wang, John Dick, Jayne Danska, Liqing Jin, Alexandre Theocharides, Sujeetha Rajakumar
  • COMPOSITIONS AND METHODS FOR TREATING HEMATOLOGICAL CANCERS TARGETING THE SIRPALPHA CD47 INTERACTION
    Publication number: 20190093174
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Application
    Filed: August 30, 2018
    Publication date: March 28, 2019
    Inventors: Jean C.Y. Wang, John Dick, Jayne Danska, Liqing Jin, Alexandre Theocharides, Sujeetha Rajakumar
  • ANTIBODIES AND ANTIBODY FRAGMENTS TARGETING SIRP-ALPHA AND THEIR USE IN TREATING HEMATOLOGIC CANCERS
    Publication number: 20140242095
    Abstract: The invention relates to modulating the SIRP?—CD47 interaction in order to treat hematological cancer and compounds therefor. In particular, there is also provided SIRP? antibodies and antibody fragments, preferably used for treating hematological cancer.
    Type: Application
    Filed: October 19, 2012
    Publication date: August 28, 2014
    Applicant: University Health Network
    Inventors: Jean C. Y. Wang, Jayne S. Danska, John Dick, Sachdev Sidhu, Maruti Uppalapati
  • Compositions and Methods for Treating Hematological Cancers Targeting the SIRPA CD47 Interaction
    Publication number: 20120189625
    Abstract: The invention relates to modulating the SIRP?-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRP? polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.
    Type: Application
    Filed: May 14, 2010
    Publication date: July 26, 2012
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Jean C.Y. Wang, John Dick, Jayne Danska, Liqing Jin, Alexandre Theocharides, Sujeetha Rajakumar