Patents by Inventor Jean Chia-Chun Chang

Jean Chia-Chun Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Co-stimulatory polypeptides
    Patent number: 7612170
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability of the polypeptides to preferentially bind a CD28 or CTLA-4 receptor at a level greater or less than the ability of human B7-1 to bind CD28 or CTLA-4, or to induce or inhibit altered level of T cell proliferation response greater compared to that generated by human B7-1. The polypeptides and polynucleotides of the invention are useful in therapeutic and prophylactic treatment methods, gene therapy applications, and vaccines.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: November 3, 2009
    Assignee: Maxygen, Inc.
    Inventors: Juha Punnonen, Alexandra L. L. Lazetic, Steven R. Leong, Jean Chia-Chun Chang