Patents by Inventor Jean-Claude Braekman

Jean-Claude Braekman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7981875
    Abstract: Compounds and pharmaceutical compositions which include 2? oxo-voruscharin and derivatives are disclosed. The compounds and pharmaceutical compositions are useful in methods of treating cancer, particularly pancreatic cancer.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: July 19, 2011
    Assignees: Unibioscreen S.A., Universite Libre de Bruxelles
    Inventors: Eric Van Quaquebeke, Jean-Claude Braekman, Gentiane Simon, Pierre Guissou, Odile Germaine Nacoulma, Janique Dewelle, Francis Darro, Robert Kiss
  • Publication number: 20080261935
    Abstract: Compounds and pharmaceutical compositions which include 2? oxo-voruscharin and derivatives are disclosed. The compounds and pharmaceutical compositions are useful in methods of treating cancer, particularly pancreatic cancer.
    Type: Application
    Filed: December 13, 2007
    Publication date: October 23, 2008
    Applicants: Unibioscreen S.A., Universite Libre de Bruxelles
    Inventors: Eric Van Quaquebeke, Jean-Claude Braekman, Gentiane Simon, Pierre Guissou, Odile Germaine Nacoulma, Janique Dewelle, Francis Darro, Robert Kiss
  • Patent number: 7320971
    Abstract: 2? oxo-voruscharin compound and derivatives thereof are disclosed as well as pharmaceutical compositions which include 2? oxo-voruscharin compound or derivatives thereof. The disclosed 2? oxo-voruscharin compound and its derivatives are useful for cancer treatment. Methods of treating cancer using the disclosed compounds are also disclosed.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: January 22, 2008
    Assignee: Unibioscreen S.A.
    Inventors: Eric Van Quaquebeke, Jean-Claude Braekman, Gentiane Simon, Pierre Guissou, Odile Germaine Nacoulma, Janique Dewelle, Francis Darro, Robert Kiss
  • Publication number: 20070123473
    Abstract: Glycosylated steroid compounds having anti-migratory activity and methods for their preparation are disclosed. Pharmaceutical compositions having an effective amount of the glycosylated steroid compounds are also disclosed. The glycosylated steroid compounds may be used as a medicament. Preparation of medicaments containing the glycosylated steroid compounds for treatment of diseases associated with cell migration, in particular, cancer, are disclosed. The glycosylated steroid compounds or pharmaceutical compositions containing the glycosylated steroid compounds may be used in the treatment of diseases associated with cell migration, in particular for the treatment of cancer.
    Type: Application
    Filed: December 17, 2004
    Publication date: May 31, 2007
    Inventors: Jean-Claude Braekman, Laurent Ingrassia, Prosper Nshimyumukiza, Eric Van Quaquebeke, Janique Dewelle, Laurent Van Den Hove, Robert Kiss, Francis Darro
  • Publication number: 20060166952
    Abstract: 2?oxo-voruscharin compound and derivatives thereof are disclosed as well as pharmaceutical compositions which include 2?oxo-voruscharin compound or derivatives thereof. The disclosed 2?oxo-voruscharin compound and its derivatives are useful for cancer treatment. Methods of treating cancer using the disclosed compounds are also disclosed.
    Type: Application
    Filed: October 9, 2003
    Publication date: July 27, 2006
    Inventors: Eric Quaquebeke, Jean-Claude Braekman, Gentiane Simon, Pierre Guissou, Odile Nacoulma, Janique Dewelle, Francis Darro, Robert Kiss
  • Publication number: 20060149045
    Abstract: The present invention relates to novel steroid compounds of Formula (IB) having anti-tumor activity. The present invention also relates to a method for the preparation of said steroid compounds. The invention further relates to a pharmaceutical composition comprising an effective amount of said steroid compounds. Furthermore, the present invention concerns the use of said steroid compounds as a medicament and in the preparation of a medicament for the treatment of cancer. The present invention also relates to the use of a steroid compound or a pharmaceutical composition comprising said steroid compound according to the invention in the treatment of cancer.
    Type: Application
    Filed: December 18, 2003
    Publication date: July 6, 2006
    Inventors: Jean-Claude Braekman, Eric Quaquebeke, Laurent Ingrassia, Janique Dewelle, Robert Kiss, Francis Darro
  • Publication number: 20060057237
    Abstract: Extracts of the plant Calotropis procera, having a pharmacological activity, in particular an anti-poisonous activity, and active compounds isolated thereof are described. Furthermore, methods for the extraction of the extracts are disclosed. Also, a pharmaceutical composition or product for the treatment of cancer which includes an effective amount of the described extracts or an active compound thereof, a therapeutic compound and optionally a pharmaceutical acceptable carrier are described.
    Type: Application
    Filed: October 9, 2003
    Publication date: March 16, 2006
    Inventors: Francis Darro, Jean-Claude Braekman, Pierre Guissou, Odile Nacoulma, Mohamed El Yazidi, Janique Dewelle, Rob Van Ginkel, Marc Van Damme, Robert Kiss
  • Patent number: 6972111
    Abstract: The invention relates to new and known compounds as well as methods for preventing the attachment of aquatic organisms to surfaces which are submerged for extensive periods of time in water. More particularly, this invention relates to the protection of submerged surfaces with new isonitrile, formamide, isocyanate and isothiocyanate anti-fouling agents.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: December 6, 2005
    Assignees: Bayer Aktiengesellschaft, Universite Libre de Bruxelles, Nederlandse Organisatie Voor Toegepast, Natuurweten-schappelijk Onderzoek & Sigma Coatings
    Inventors: Franz Kunisch, Martin Kugler, Jean-Claude Braekman, Mark Plehiers, Gabriele Ferrari, Marcel Vos
  • Patent number: 6929685
    Abstract: The invention relates to methods for preventing the attachment of aquatic organisms to surfaces that are submerged for extension periods of time in water. More particularly, this invention relates to the protection of submerged surfaces with alkylamine derivatives as antifouling agents. The invention is beneficiary for the environment in that it will permit the use of copper- and tin-free paints.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: August 16, 2005
    Assignee: Bayer Atiengesellschaft
    Inventors: Daniel Bernard, Jean-Claude Braekman, Gabriele Ferrari, Martin Kugler, Franz Kunisch, Mark Plehiers, Marcel Vos
  • Publication number: 20040118318
    Abstract: The invention relates to methods for preventing the attachment of aquatic organisms to surfaces that are submerged for extensive periods of time in water. More particularly, this invention relates to the protection of submerged surfaces with alkylamine derivatives as antifouling agents. The invention is beneficiary for the environment in that it will permit the use of copper- and tin-free paints.
    Type: Application
    Filed: January 14, 2004
    Publication date: June 24, 2004
    Inventors: Daniel Bernard, Jean-Claude Braekman, Gabriele Ferrari, Martin Kugler, Franz Kunisch, Mark Plehiers, Marcel Vos