Patents by Inventor Jean-Claude Guillemot

Jean-Claude Guillemot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xanthine derivative inhibitors of BET proteins
    Patent number: 11225481
    Abstract: This invention relates to xanthine derivative compounds that are inhibitors of BET bromodomains proteins, the method of preparation thereof and applications thereof.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: January 18, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT JEAN PAOLI & IRENE CALMETTES
    Inventors: Xavier Morelli, Sébastien Combes, Jean-Claude Guillemot, Stéphanie Betzi, Yves Collette, Philippe Roche, Adrien Lugari, Sabine Milhas, Brigitt Raux, Iuliia Voitovich
  • XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS
    Publication number: 20190292186
    Abstract: This invention relates to xanthine derivative compounds that are inhibitors of BET bromodomains proteins, the method of preparation thereof and applications thereof.
    Type: Application
    Filed: December 27, 2016
    Publication date: September 26, 2019
    Inventors: Xavier MORELLI, Sébastien COMBES, Jean-Claude GUILLEMOT, Stéphanie BETZI, Yves COLLETTE, Philippe ROCHE, Adrein LUGARI, Sabine MILHAS, Brigit RAUX, luliia VOITOVICH
  • Serpins: methods of therapeutic ?-cell regeneration and function
    Patent number: 9763998
    Abstract: Compositions and methods of use are provided for improving ? cell function and promoting pancreatic ? cell proliferation in vitro, in vivo and ex vivo. The active agents of the pending invention comprise Serpin family peptides (e.g., SerpinB1), functional and structural analogs of Serpin family peptides and nucleic acids encoding Serpin family peptides, as well as active fragments thereof.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: September 19, 2017
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Rohit N. Kulkarni, Abdelfattah El Ouaamari, Daniel Margerie, Matthias Lohmann, Jean Claude Guillemot, Denis Loyaux
  • SERPINS: METHODS OF THERAPEUTIC BETA-CELL REGENERATION AND FUNCTION
    Publication number: 20160002316
    Abstract: Compositions and methods of use are provided for improving ? cell function and promoting pancreatic ? cell proliferation in vitro, in vivo and ex vivo. The active agents of the pending invention comprise Serpin family peptides (e.g., SerpinB1), functional and structural analogs of Serpin family peptides and nucleic acids encoding Serpin family peptides, as well as active fragments thereof.
    Type: Application
    Filed: February 21, 2014
    Publication date: January 7, 2016
    Applicants: JOSLIN DIABETES CENTER, SANOFI
    Inventors: Daniel MARGERIE, Matthias LOHMANN, Jean Claude GUILLEMOT, Denis LOYAUX, Rohit KULKARNI, Abdelfattah EL OUAAMARI
  • SERPINS: METHODS OF THERAPEUTIC B-CELL REGENERATION AND FUNCTION
    Publication number: 20150366940
    Abstract: Compositions and methods of use are provided for improving ? cell function and promoting pancreatic ? cell proliferation in vitro, in vivo and ex vivo. The active agents of the pending invention comprise Serpin family peptides (e.g., SerpinB1), functional and structural analogs of Serpin family peptides and nucleic acids encoding Serpin family peptides, as well as active fragments thereof.
    Type: Application
    Filed: February 21, 2014
    Publication date: December 24, 2015
    Inventors: Rohit N. Kulkarni, Abdelfattah El Ouaamari, Daniel Margerie, Matthias Lohmann, Jean Claude Guillemot, Denis Loyaux
  • Protein having interleukin 13 activity, recombinant DNA coding for this protein, transformed cells and microorganisms
    Patent number: 5652123
    Abstract: The subject of the present invention is a protein having cytokine type activity, or a precursor of this protein, which comprises the following amino acid sequence (a1): ##STR1## in which Xaa represents Asp or Gly.
    Type: Grant
    Filed: January 11, 1995
    Date of Patent: July 29, 1997
    Assignee: Elf Sanofi
    Inventors: Daniel Caput, Pascual Ferrara, Jean-Claude Guillemot, Mourad Kaghad, Christine Labit-Le Bouteiller, Pascal Leplatois, Marilyn Magazin, Adrian Minty
  • Urate oxidase activity protein, recombinant gene coding therefor, expression vector, micro-organisms and transformed cells
    Patent number: 5541098
    Abstract: The invention concerns a new urate oxidase activity protein which has the following sequence (SEQ ID NO:1): ##STR1## optionally preceded by a methionine, or in that it may present a degree of substantial homology with this sequence.The invention is also aimed at medicines containing this protein as well as the genetic engineering implements to obtain it.
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: July 30, 1996
    Assignee: Sanofi
    Inventors: Daniel Caput, Pascual Ferrara, Jean-Claude Guillemot, Mourad Kaghad, Richard LeGoux, G erard Loison, Elisabeth Larbre, Johannes Lupker, Pascal Leplatois, Marc Salome, Patrick Laurent
  • Urate oxidase activity protein, recombinant gene coding therefor, expression vector, micro-organisms and transformed cells
    Patent number: 5382518
    Abstract: The invention concerns a new urate oxidase activity protein which has the following sequence:______________________________________ Ser Ala Val Lys Ala Ala Arg Tyr Gly Lys Asp Asn Val Arg Val Tyr Lys Val His Lys Asp Glu Lys Thr Gly Val Gln Thr Val Tyr Glu Met Thr Val Cys Val Leu Leu Glu Gly Glu Ile Glu Thr Ser Tyr Thr Lys Ala Asp Asn Ser Val Ile Val Ala Thr Asp Ser Ile Lys Asn Thr Ile Tyr Ile Thr Ala Lys Gln Asn Pro Val Thr Pro Pro Glu Leu Phe Gly Ser Ile Leu Gly Thr His Phe Ile Glu Lys Tyr Asn His Ile His Ala Ala His Val Asn Ile Val Cys His Arg Trp Thr Arg Met Asp Ile Asp Gly Lys Pro His Pro His Ser Phe Ile Arg Asp Ser Glu Glu Lys Arg Asn Val Gln Val Asp Val Val Glu Gly Lys Gly Ile Asp Ile Lys Ser Ser Leu Ser Gly Leu Thr Val Leu Lys Ser Thr Asn Ser Gln Phe Trp Gly Phe Leu Arg Asp Glu Tyr Thr Thr Leu Lys Glu Thr Trp Asp Arg Ile Leu Ser Thr Asp Val Asp Ala Thr Trp Gln Trp Lys Asn Phe Ser Gly Leu Gln Glu Val Arg Ser His Val Pro Lys Phe Asp Ala Thr Trp Ala Thr Ala Arg Glu Val Thr Leu Lys Thr Phe Ala Glu Asp Asn
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: January 17, 1995
    Assignee: Sanofi
    Inventors: Daniel Caput, Pascual Ferrara, Jean-Claude Guillemot, Mourad Kaghad, Richard Legoux, Gerard Loison, Elisabeth Larbre, Johannes Lupker, Pascal Leplatois, Marc Salome, Patrick Laurent