Patents by Inventor Jean-Claude Hilscher

Jean-Claude Hilscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use and process for their production
    Patent number: 5733522
    Abstract: The invention relates to complex compound as well as their salts consisting of at least one metal ion and one complexing agent of general formula I ##STR1## in which Z.sup.1, Z.sup.2 and s have different meanings, as well as their use for the production of agents for radiation therapy and for NMR diagnosis and diagnostic radiology, especially for contrasting the hepatobiliary system. Further, the invention relates to a process for the production of these compounds and agents.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: March 31, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Heribert Schmitt-Willich, Johannes Platzek, Heinz Gries, Bernd Raduchel, Orlin Petrov, Andreas Muhler, Thomas Frenzel, Hubert Vogler, Hans Bauer, Klaus Nickisch, Jean-Claude Hilscher
  • Process for the production of C-substituted diethylenetriamines
    Patent number: 5654467
    Abstract: The invention relates to a process for the production of C-substituted diethylenetriamines of general formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have different meanings.
    Type: Grant
    Filed: October 12, 1995
    Date of Patent: August 5, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Orlin Petrov, Jean-Claude Hilscher, Klaus Nickisch, Heribert Schmitt-Willich, Heinz Gries, Bernd Raduchel, Johannes Platzek
  • (2-Haloergolinyl)-N'-N'-diethylurea compounds useful as medicinal agents E.G., as neuroleptics
    Patent number: 4853390
    Abstract: (2-Haloergolinyl)-N',N'-diethylurea derivatives of Formula I ##STR1## and the salts thereof, wherein R is hydrogen, alkyl of up to 6 carbon atoms, or alkenyl of up to 3 carbon atoms,X is halogen, ##STR2## is a CC single or CC double bond, and the urea residue in the 8-position can be in the .alpha.- or .beta.-configuration, have neuropsychotropic properties.As a result, they are excellently suitable for treatment of psychotic disturbances and emesis.
    Type: Grant
    Filed: March 2, 1987
    Date of Patent: August 1, 1989
    Assignee: Schering Aktiengesellschaft
    Inventors: Jean-Claude Hilscher, Wolfgang Kehr, Gerhard Sauer, Herbert Schneider, Helmut Wachtel
  • Process for the preparation of 3-hemisulfate-17.alpha.-hydroxy steroids
    Patent number: 4021458
    Abstract: 3-Hemisulfate sodium salts of 17.alpha.-hydroxy steroids of the formula ##STR1## wherein R.sub.1 is H, CH.sub.3 or C.sub.2 H.sub.5 and .DELTA. is one or more additional double bonds optionally present in the B and/or C rings are produced by treating a 17-mono ester of a carboxylic acid of up to 15 carbon atoms of the corresponding 3,17.alpha.-dihydroxy steroid with the reaction product of pyridine or like amine and sulfur trioxide or reactive functional derivative thereof and, without isolation thereof, saponifying the resultant reaction product with alkali, preferably a sodium alcoholate or hydroxide in a lower alcohol.
    Type: Grant
    Filed: April 15, 1975
    Date of Patent: May 3, 1977
    Assignee: Schering Aktiengesellschaft
    Inventors: Hanfried Arnold, Jean-Claude Hilscher, Reinhold Wieske
  • Steroid ether splitting
    Patent number: 3956348
    Abstract: Ethers of aromatic steroids are cleaved to regenerate the hydroxy group with aluminum hydride, dialkylaluminum hydride or trialkylaluminum.
    Type: Grant
    Filed: February 25, 1975
    Date of Patent: May 11, 1976
    Assignee: Schering Aktiengesellschaft
    Inventor: Jean-Claude Hilscher