Patents by Inventor Jean-Claude Kizirian

Jean-Claude Kizirian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing olopatadine and/or a pharmaceutically acceptable salt thereof
    Patent number: 8835655
    Abstract: The present invention relates to a process for the preparation of olopatadine and, more particularly, to an improved method of synthesizing olopatadine which comprises reacting a dibenz[b,e]oxepin-11-one derivative of formula (III) and a suitable reagent under Witting condition, and to the intermediate 11-[(Z)-3-(dimethylamino)-propylidene]-6-11-dihydrodibenz[b,e]-oxepin-2-acet-amide p-toluensulfonate salt.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: September 16, 2014
    Assignee: Zach System S.p.A
    Inventors: Alberto Guidi, Filippo Chiarello, Gianmauro Orru', Massimo Verzini, Livius Cotarca, Jean-Claude Kizirian, Elisenda Trepat Guixer, Francisco Marquillas Olondriz
  • PROCESS FOR PREPARING OLOPATADINE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
    Publication number: 20120016138
    Abstract: The present invention relates to a process for the preparation of olopatadine and, more particularly, to an improved method of synthesizing olopatadine which comprises reacting a dibenz[b,e]oxepin-11-one derivative of formula (III) and a suitable reagent under Witting condition, and to the intermediate 11-[(Z)-3-(dimethylamino)-propylidene]-6-11-dihydrodibenz[b,e]-oxepin-2-acet-amide p-toluensulfonate salt.
    Type: Application
    Filed: February 1, 2010
    Publication date: January 19, 2012
    Applicant: ZACH SYSTEM S.P.A.
    Inventors: Alberto Guidi, Filippo Chiarello, Gianmauro Orru', Massimo Verzini, Livius Cotarca, Jean-Claude Kizirian, Elisenda Trepat Guixer, Francisco Marquillas Olondriz