Patents by Inventor Jean-Claude Maurel

Jean-Claude Maurel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT AND PREVENTION OF INJURY DUE TO RADIATION EXPOSURE
    Publication number: 20240000832
    Abstract: The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.
    Type: Application
    Filed: September 14, 2023
    Publication date: January 4, 2024
    Inventors: Elsa COMPTE, Patrick MAUREL, Sophie GRIVES-JERPHAGNON, Cyril LAVAUD, Lorraine BENIGNO-ANTON, Jean-Claude MAUREL
  • Treatment and prevention of injury due to radiation exposure
    Patent number: 11793831
    Abstract: The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: October 24, 2023
    Assignee: MEDESIS PHARMA
    Inventors: Elsa Compte, Patrick Maurel, Sophie Grives-Jerphagnon, Cyril Lavaud, Lorraine Benigno-Anton, Jean-Claude Maurel
  • TREATMENT OF COVID-19 WITH REVERSE MICELLE SYSTEM COMPRISING UNMODIFIED OLIGONUCLEOTIDES
    Publication number: 20230144739
    Abstract: The present invention relates to specific reverse micelle system of the invention which allows the administration and intracellular delivery of unmodified oligonucleotide, such as siRNA, targeting one or more genes of the SARS-CoV-2 virus. The reverse micelle system of the invention is thus particularly useful for the treatment of the viral pathology linked to the SARS-CoV-2 virus.
    Type: Application
    Filed: March 15, 2021
    Publication date: May 11, 2023
    Inventors: Jean-Claude MAUREL, Abdelkader MOURI, Hervé SEITZ, Sophie MOCKLY
  • TREATMENT OF COVID-19 WITH REVERSE MICELLE SYSTEM COMPRISING UNMODIFIED OLIGONUCLEOTIDES
    Publication number: 20230129386
    Abstract: The present disclosure relates to specific reverse micelle system that allows for the administration and intracellular delivery of unmodified oligonucleotide, such as siRNA, targeting one or more genes of the SARS-CoV-2 virus. The reverse micelle systems described herein are particularly useful for the treatment of COVID-19.
    Type: Application
    Filed: September 15, 2022
    Publication date: April 27, 2023
    Inventors: Hervé SEITZ, Abdelkader MOURI, Jean-Claude MAUREL
  • In situ preparation of cyano-bridged metal nanoparticles within a biocompatible reverse micellar system
    Patent number: 11278568
    Abstract: The present invention relates to a method for in situ preparation of cyano-bridged coordination polymers as metal nanoparticles within a biocompatible reverse micellar system by mixing at least two reverse micellar systems, each one containing at least one metal salt precursor. The invention also relates to the stabilization of theses nanoparticles by using a biocompatible reverse micellar system. This system takes part of the synthesis as a nanoreactor which comprises at least an acylglycerol, a sterol, lecithin, ethanol and water for the preparation of stable cyano-bridged metal nanoparticles without any use of additional stabilizer agent.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: March 22, 2022
    Assignees: MEDESIS PHARMA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER
    Inventors: Jean-Claude Maurel, Elsa Compte, Cyril Lavaud, Yannick Guari, Joulia Guari, Jérôme Long
  • TREATMENT AND PREVENTION OF INJURY DUE TO RADIATION EXPOSURE
    Publication number: 20210315931
    Abstract: The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.
    Type: Application
    Filed: July 5, 2019
    Publication date: October 14, 2021
    Inventors: Elsa COMPTE, Patrick MAUREL, Sophie GRIVES-JERPHAGNON, Cyril LAVAUD, Lorraine BENIGNO-ANTON, Jean-Claude MAUREL
  • USE OF A REVERSE-MICELLAR SYSTEM FOR DELIVERING CHELATORS OF RADIONUCLIDES AND METALS
    Publication number: 20190192420
    Abstract: The present invention relates to reverse-micellar systems comprising at least an active agent, an acylglycerol, a sterol, lecithin, ethanol and water, for use in chelation and/or sequestering of a radionuclide and/or a metal in a patient. The invention also relates to the reverse-micellar systems and to pharmaceutical compositions comprising said reverse-micellar systems.
    Type: Application
    Filed: November 26, 2018
    Publication date: June 27, 2019
    Inventors: Caroline BAUER, Elsa COMPTE, Olivier GREMY, Laurent MICCOLI, Jaime Francisco ANGULO-MORA, Jean-Claude MAUREL
  • Use of a reverse-micellar system for delivering chelators of radionuclides and metals
    Patent number: 10172954
    Abstract: The present invention relates to reverse-micellar systems comprising at least an active agent, an acylglycerol, a sterol, lecithin, ethanol and water, for use in chelation and/or sequestering of a radionuclide and/or a metal in a patient. The invention also relates to the reverse-micellar systems and to pharmaceutical compositions comprising said reverse-micellar systems.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: January 8, 2019
    Assignee: MEDESIS PHARMA
    Inventors: Caroline Bauer, Elsa Compte, Olivier Gremy, Laurent Miccoli, Jaime Francisco Angulo-Mora, Jean-Claude Maurel
  • IN SITU PREPARATION OF CYANO-BRIDGED METAL NANOPARTICLES WITHIN A BIOCOMPATIBLE REVERSE MICELLAR SYSTEM
    Publication number: 20180200295
    Abstract: The present invention relates to a method for in situ preparation of cyano-bridged coordination polymers as metal nanoparticles within a biocompatible reverse micellar system by mixing at least two reverse micellar systems, each one containing at least one metal salt precursor. The invention also relates to the stabilization of theses nanoparticles by using a biocompatible reverse micellar system. This system takes part of the synthesis as a nanoreactor which comprises at least an acylglycerol, a sterol, lecithin, ethanol and water for the preparation of stable cyano-bridged metal nanoparticles without any use of additional stabilizer agent.
    Type: Application
    Filed: July 8, 2016
    Publication date: July 19, 2018
    Inventors: Jean-Claude MAUREL, Elsa COMPTE, Cyril LAVAUD, Yannick GUARI, Joulia GUARI, Jérôme LONG
  • Reverse micelle system comprising metal ions and use thereof
    Patent number: 9592218
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: March 14, 2017
    Assignee: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • USE OF A REVERSE-MICELLAR SYSTEM FOR DELIVERING CHELATORS OF RADIONUCLIDES AND METALS
    Publication number: 20170035909
    Abstract: The present invention relates to reverse-micellar systems comprising at least an active agent, an acylglycerol, a sterol, lecithin, ethanol and water, for use in chelation and/or sequestering of a radionuclide and/or a metal in a patient. The invention also relates to the reverse-micellar systems and to pharmaceutical compositions comprising said reverse-micellar systems.
    Type: Application
    Filed: February 17, 2015
    Publication date: February 9, 2017
    Inventors: Caroline BAUER, Elsa COMPTE, Olivier GREMY, Laurent MICCOLI, Jaime Francisco ANGULO-MORA, Jean-Claude MAUREL
  • Reverse micelle system comprising nucleic acids and use thereof
    Patent number: 9452136
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: September 27, 2016
    Assignee: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Reverse micelle compositions for delivery of metal cations comprising a diglyceride and a phytosterol and method of preparation
    Patent number: 9173838
    Abstract: The present invention relates to a method for the preparation of reverse micelles based on sterols, acylglycerols and metal salt and to reverse micelles obtained thereby. They are advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: November 3, 2015
    Assignee: MEDESIS PHARMA SA
    Inventor: Jean-Claude Maurel
  • REVERSE MICELLE SYSTEM COMPRISING NUCLEIC ACIDS AND USE THEREOF
    Publication number: 20150050347
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: October 22, 2014
    Publication date: February 19, 2015
    Inventor: JEAN-CLAUDE MAUREL
  • Reverse micelle system comprising nucleic acids and use thereof
    Patent number: 8877237
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: November 4, 2014
    Assignee: Medesis Pharma
    Inventor: Jean-Claude Maurel
  • Reverse micelles based on phytosterols and acylglycerols and therapeutic uses thereof
    Patent number: 8637314
    Abstract: The present invention relates generally to reverse-m ice liar system comprising a hydrosoluble therapeutically active agent. Reverse micelles according to the invention are particularly useful to deliver drugs. The present invention also relates to pharmaceutical composition comprising said reverse micelles and methods for preparing the same.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: January 28, 2014
    Assignee: Medesis Pharma SA
    Inventor: Jean-Claude Maurel
  • REVERSE MICELLE SYSTEM COMPRISING NUCLEIC ACIDS AND USE THEREOF
    Publication number: 20130065944
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: March 24, 2011
    Publication date: March 14, 2013
    Applicant: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • REVERSE MICELLE SYSTEM COMPRISING METAL IONS AND USE THEREOF
    Publication number: 20130052279
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: March 24, 2011
    Publication date: February 28, 2013
    Applicant: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • MANGANESE BASED ORGANOMETALLIC COMPLEXES, PHARMACEUTICAL COMPOSITIONS AND DIETETIC PRODUCTS
    Publication number: 20090247492
    Abstract: The invention relates to compounds and their uses, particularly in the pharmaceutical and dietetic industries. The invention discloses complexes having Mn-SOD like activities, as well as methods for treating various diseases associated with oxidative stress, including cancer and inflammatory conditions, by administering said compounds. It further deals with pharmaceutical compositions or dietetic products comprising said compounds, more particularly useful to treat various diseases or disorders, in particular useful in the prevention or treatment of a disease involving an oxidative stress.
    Type: Application
    Filed: May 4, 2009
    Publication date: October 1, 2009
    Applicant: MEDESIS PHARMA S.A.,
    Inventors: Jean-Claude Maurel, Claude-Alain Cudennec
  • METHODS FOR PREPARING REVERSE MICELLES BASED ON STEROLS AND ACYLGLYCEROLS FOR THE DELIVERY OF METAL IONS
    Publication number: 20090087477
    Abstract: The present invention relates to a method for the preparation of reverse micelles based on sterols, acylglycerols and metal salt and to reverse micelles obtained thereby. They are advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: November 2, 2005
    Publication date: April 2, 2009
    Inventor: Jean-Claude Maurel