Patents by Inventor Jean-Claude Ortuno

Jean-Claude Ortuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11833162
    Abstract: Compound of formula (I): wherein A1, A2, Ra, Rb, Rc, Rd, R3, R4, X, Y and G are as defined in the description, and their use in the manufacture of medicaments.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: December 5, 2023
    Assignees: LES LABORATOIRES SERVIER, VERNALIS (R&D) LTD
    Inventors: Jérôme-Benoît Starck, Didier Durand, I-Jen Chen, Arnaud Le Tiran, Jean-Claude Ortuno, Miklós Nyerges, Melinda Ligeti, Imre Fejes
  • Publication number: 20200253993
    Abstract: Compound of formula (I): wherein A1, A2, Ra, Rb, Rc, Rd, R3, R4, X, Y and G are as defined in the description, and their use in the manufacture of medicaments.
    Type: Application
    Filed: October 24, 2018
    Publication date: August 13, 2020
    Inventors: Jérôme-Benoît STARCK, Didier DURAND, I-Jen CHEN, Arnaud LE TIRAN, Jean-Claude ORTUNO, Miklós NYERGES, Melinda LIGETI, Imre FEJES
  • Patent number: 8653073
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: February 18, 2014
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Imre Fejes, Michael Burnbridge, John Hickman, Alain Pierre
  • Patent number: 8541412
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: September 24, 2013
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Imre Fejes, Vincent Lacoste, Pauline Lacoste
  • Patent number: 8133889
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: March 13, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, legal representative, Pauline Lacoste, legal representative, Imre Fejes, Michael Burbridge, John Hickman, Alain Pierre
  • Publication number: 20120046287
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Application
    Filed: November 2, 2011
    Publication date: February 23, 2012
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, Pauline Lacoste, Imre Fejes
  • Publication number: 20110034460
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Application
    Filed: August 4, 2010
    Publication date: February 10, 2011
    Applicant: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, Pauline Lacoste, Imre Fejes, Michael Burbridge, John Hickman, Alain Pierre
  • Patent number: 7442692
    Abstract: A compound selected from those of formula (I): wherein: R3 represents a hydrogen atom, and R1 and R2 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, or R1 represents a hydrogen atom, and R2 and R3 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, n represents 1 or 2, —X— represents a group selected from —(CH2)m—O-Ak-, —(CH2)m—NR4-Ak-, —(CO)—NR4-Ak- and —(CH2)m—NR4-(CO)—, m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and R4 represents a hydrogen atom or an alkyl group, Ar represents an aryl or heteroaryl group, its enantiomers, diasteroisomers, and addition salts thereof with a pharmaceutically acceptable acid.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: October 28, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Guillaume De Nanteuil, Bernard Portevin, Philippe Gloanec, Mark Millan, Jean-Claude Ortuno, Clotilde Mannoury La Cour, Alain Gobert
  • Publication number: 20060223830
    Abstract: A compound selected from those of formula (I): wherein: R3 represents a hydrogen atom, and R1 and R2 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, ?or R1 represents a hydrogen atom, and R2 and R3 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, n represents 1 or 2, —X— represents a group selected from —(CH2)m—O-Ak-, —(CH2)m—NR4-Ak-, —(CO)—NR4-Ak- and —(CH2)m—NR4-(CO)—, ?m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and R4 represents a hydrogen atom or an alkyl group, Ar represents an aryl or heteroaryl group, its enantiomers, diasteroisomers, and addition salts thereof with a pharmaceutically acceptable acid.
    Type: Application
    Filed: March 29, 2006
    Publication date: October 5, 2006
    Inventors: Guillaume De Nanteuil, Bernard Portevin, Philippe Gloanec, Mark Millan, Jean-Claude Ortuno, Clotilde Mannoury La Cour, Alain Gobert
  • Publication number: 20040029875
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: April 11, 2003
    Publication date: February 12, 2004
    Inventors: Jean-Luc Fauchere, Jean-Claude Ortuno, Nigel Levens, Susana Chamorro, Jean Albert Boutin
  • Patent number: 6596749
    Abstract: Method of treating with compounds of formula (I): wherein: n is 0 or 1, W represents —CO— or S(O)q and q is 0, 1 or 2, G represents a G1, G2, G3 or G4 group as defined in the description, Z represents alkyl, aryl, heteroaryl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, A represents a grouping selected from —A2—, —A1—A2—, —A2—A1—, and —A1—A2—A1— wherein A1 is alkylene and A2 represents phenylene, cycloalkylene, naphthylene or heteroarylene each optionally substituted, R represents hydrogen, alkyl, aryl, heteroaryl, arylalkyl arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, R1 represents alkyl, aryl, heteroaryl, arylalkyl arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, and medicinal products containing the
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: July 22, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Luc Fauchere, Jean-Claude Ortuno, Jacques Duhault, Jean Albert Boutin, Nigel Levens
  • Publication number: 20010018522
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: March 5, 2001
    Publication date: August 30, 2001
    Inventors: Jean-Luc Fauchere, Jean-Claude Ortuno, Jacques Duhault, Jean Albert Boutin, Nigel Levens
  • Patent number: 6245916
    Abstract: Compound of formula (I): wherein: n is 0 or 1, W represents —CO— or S(O)q and q is 0, 1 or 2, G represents a G1, G2, G3 or G4 group as defined in the description, Z represents alkyl, aryl, heteroaryl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: June 12, 2001
    Assignee: Adir et Compagnie
    Inventors: Jean-Luc Fauchere, Jean-Claude Ortuno, Jacques Duhault, Jean Albert Boutin, Nigel Levens