Patents by Inventor Jean-Claude Pascal

Jean-Claude Pascal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11053274
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) said process comprising the steps of: a) reacting a compound of formula (II), with an acylating or a silylating agent to produce a compound of formula (III), wherein P1 and P2 are each independently a protecting group selected from R2—Si—R3R4, or R1CO—, wherein R1 is a group selected from C1-6alkyl or C3-6cycloalkyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; b) reacting the compound of formula (III) in the presence of palladium acetate or a derivative thereof to produce compound of formula (IV); and c) reacting the compound of formula (IV) with a reducing agent to produce compound of formula (I).
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: July 6, 2021
    Assignee: ESTETRA S.P.R.L.
    Inventor: Jean-Claude Pascal
  • Patent number: 11053273
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) comprising the steps of a) reacting a compound of formula (II) with a silylating or an acylating agent to produce compound of formula (III), wherein P1 is a protecting group selected from R2—Si—R3R4 or R1CO—, R1 is a group selected from C1-6alkyl or C3-6cycloalkyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; b) halogenation or sulfinylation of the compound of formula (III) to produce a compound of formula (IV); wherein X is halo, or —O—SO—R5, and R5 is a group selected from C6-10aryl or heteroaryl, each group being optionally substituted by one or more substituents independently selected from chloro or C1-4alkyl; c) dehalogenation or desulfinylation of t
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: July 6, 2021
    Assignee: ESTETRA S.P.R.L.
    Inventor: Jean-Claude Pascal
  • Patent number: 9630949
    Abstract: The present invention relates to novel compounds derived from oxoazetidine corresponding to general formula (I) to the compositions containing same, to the process for preparation thereof and to the use thereof in pharmaceutical or cosmetic compositions.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: April 25, 2017
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Claire Bouix-Peter, Itaru Suzuki, Nicolas Rodeville, Pascale Mauvais, Jean-Claude Pascal
  • Publication number: 20160280650
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Application
    Filed: June 3, 2016
    Publication date: September 29, 2016
    Inventors: Laurence CLARY, Sandrine CHAMBON, Laurent CHANTALAT, Carine ROSIGNOLI, Olivier ROYE, Jean-Claude PASCAL, Marlene SCHUPPLI-NOLLET
  • Patent number: 9365529
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: June 14, 2016
    Assignee: GALDERMA RESEARCH & DEVLOPMENT
    Inventors: Laurence Clary, Sandrine Chambon, Laurent Chantalat, Carine Rosignoli, Olivier Roye, Jean-Claude Pascal, Marlene Schuppli-Nollet
  • Patent number: 9266848
    Abstract: The present invention relates to novel benzene-carboxamide compounds having a structure that corresponds to the general formula (I) below: and also to their method of synthesis and to their use in pharmaceutical compositions intended for use in human or veterinary medicine or else to their use in cosmetic compositions.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: February 23, 2016
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Laurence Clary, Jean-Claude Pascal
  • Patent number: 9102607
    Abstract: Compounds of the following general formula (I): are described. Also described, are processes of their preparation and their use in therapeutic applications.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: August 11, 2015
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Claire Bouix-Peter, Jean-Claude Pascal, Nicolas Rodeville
  • Publication number: 20150158834
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 11, 2015
    Inventors: Laurence CLARY, Sandrine CHAMBON, Laurent CHANTALAT, Carine ROSIGNOLI, Olivier ROYE, Jean-Claude PASCAL, Marlene SCHUPPLI-NOLLET
  • Patent number: 8987484
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I), hydrates or solvates thereof.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: March 24, 2015
    Assignee: Estetra S.P.R.L.
    Inventor: Jean-Claude Pascal
  • Patent number: 8980897
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: March 17, 2015
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Sandrine Chambon, Laurent Chantalat, Carine Rosignoli, Olivier Roye, Jean-Claude Pascal, Marlene Schuppli-Nollet
  • Publication number: 20150045559
    Abstract: The present invention relates to novel compounds derived from oxoazetidine corresponding to general formula (I) to the compositions containing same, to the process for preparation thereof and to the use thereof in pharmaceutical or cosmetic compositions.
    Type: Application
    Filed: September 26, 2014
    Publication date: February 12, 2015
    Inventors: Claire BOUIX-PETER, Itaru SUZUKI, Nicolas RODEVILLE, Pascale MAUVAIS, Jean-Claude PASCAL
  • Patent number: 8901357
    Abstract: The use of compounds in the treatment of skin disorders is described. In particular, compounds having the general formula (I): are described. A process for preparing such compounds and their cosmetic or dermatological use are also described. The described compounds can act as bactericides. As a result, they can be useful in the treatment of conditions associated with the presence of bacteria, more specifically of P. acnes.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: December 2, 2014
    Assignee: Galderma Research & Development
    Inventors: Nicolas Rodeville, Jean-Claude Pascal, Claire Bouix-Peter
  • Patent number: 8871187
    Abstract: Compounds derived from oxoazetidine corresponding to general formula (I) compositions containing same, processes for their preparation and their use in pharmaceutical or cosmetic compositions are described.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: October 28, 2014
    Assignee: Galderma Research & Development
    Inventors: Claire Bouix-Peter, Itaru Suzuki, Nicolas Rodeville, Pascale Mauvais, Jean-Claude Pascal
  • Publication number: 20140243539
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I), hydrates or solvates thereof.
    Type: Application
    Filed: October 5, 2012
    Publication date: August 28, 2014
    Applicant: Estetra S.P.R.L.
    Inventor: Jean-Claude Pascal
  • Patent number: 8729312
    Abstract: Compounds of the following general formula (I): are described. Also described, are methods of preparing the compounds and their use in therapeutics.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: May 20, 2014
    Assignee: Galderma Research & Development
    Inventors: Claire Bouix-Peter, Jean-Claude Pascal, Nicolas Rodeville
  • Publication number: 20140107358
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) said process comprising the steps of: a) reacting a compound of formula (II), with an acylating or a silylating agent to produce a compound of formula (III), wherein P1 and P2 are each independently a protecting group selected from R2?Si—R3R4, or R1CO—, wherein R1 is a group selected from C1-6alkyl or C3-6cycloalkyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; b) reacting the compound of formula (III) in the presence of palladium acetate or a derivative thereof to produce compound of formula (IV); and c) reacting the compound of formula (IV) with a reducing agent to produce compound of formula (I).
    Type: Application
    Filed: June 1, 2012
    Publication date: April 17, 2014
    Applicant: ESTETRA S.A.
    Inventor: Jean-Claude Pascal
  • Publication number: 20140107129
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Application
    Filed: December 11, 2013
    Publication date: April 17, 2014
    Applicant: Galderma Research & Development
    Inventors: Laurence CLARY, Sandrine CHAMBON, Laurent CHANTALAT, Carine ROSIGNOLI, Olivier ROYE, Jean-Claude PASCAL, Marlene SCHUPPLI-NOLLET
  • Publication number: 20140107091
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) comprising the steps of a) reacting a compound of formula (II) with a silylating or an acylating agent to produce compound of formula (III), wherein P1 is a protecting group selected from R2Si—R3R4 or R1CO—, R1 is a group selected from C1-6alkyl or C3-6cycloalkyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; b) halogenation or sulfinylation of the compound of formula (III) to produce a compound of formula (IV); wherein X is halo, or —O—SO—R5, and R5 is a group selected from C6-10aryl or heteroaryl, each group being optionally substituted by one or more substituents independently selected from chloro or C1-4alkyl; c) dehalogenation or desulfinylation of th
    Type: Application
    Filed: June 1, 2012
    Publication date: April 17, 2014
    Applicant: ESTETRA S.A.
    Inventor: Jean-Claude Pascal
  • Patent number: 8633196
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: January 21, 2014
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Sandrine Chambon, Laurent Chantalat, Carine Rosignoli, Olivier Roye, Jean-Claude Pascal, Marlène Schuppli-Nollet
  • Publication number: 20130178648
    Abstract: Compounds of the following general formula (I): are described. Also described, are methods of preparing the compounds and their use in therapeutics.
    Type: Application
    Filed: December 10, 2010
    Publication date: July 11, 2013
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Claire Bouix-Peter, Jean-Claude Pascal, Nicolas Rodeville