Patents by Inventor Jean-Claude Sirard

Jean-Claude Sirard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza
    Patent number: 10736937
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza. In particular, the present invention relates to a method of treating a bacterial superinfection post-influenza in a subject in need thereof comprising administering the subject with a therapeutically effective amount of a flagellin polypeptide optionally in combination with at least one antibiotic.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: August 11, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE LILLE, INSTITUT PASTEUR DE LILLE
    Inventors: Jean-Claude Sirard, Christophe Carnoy, François Trottein, Rémi Porte
  • Methods and pharmaceutical compositions for the treatment of respiratory tract infections
    Patent number: 10426816
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of respiratory tract infections. More particularly, the present invention relates to a TLR5 agonist for use in a method for treating a respiratory tract infection.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: October 1, 2019
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Institut Pasteur de Lille
    Inventors: Jean-Claude Sirard, Jose A. Chabalgoity
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
    Publication number: 20180344807
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of acute exacerbation of chronic obstructive pulmonary disease. In particular, the present invention relates to a method of treating acute exacerbation of chronic obstructive pulmonary disease in a subject in need thereof comprising administering the subject with a therapeutically effective amount of a flagellin polypeptide.
    Type: Application
    Filed: July 30, 2018
    Publication date: December 6, 2018
    Inventors: Philippe GOSSET, Muriel PICHAVANT, Jean-Claude SIRARD, Bachirou KONE, Magdiel PEREZ-CRUZ
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL SUPERINFECTIONS POST-INFLUENZA
    Publication number: 20180264077
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza. In particular, the present invention relates to a method of treating a bacterial superinfection post-influenza in a subject in need thereof comprising administering the subject with a therapeutically effective amount of a flagellin polypeptide optionally in combination with at least one antibiotic.
    Type: Application
    Filed: December 22, 2015
    Publication date: September 20, 2018
    Inventors: Jean-Claude SIRARD, Christophe CARNOY, François TROTTEIN, Rémi PORTE
  • Immunoadjuvant flagellin-based compounds and use thereof
    Patent number: 9956284
    Abstract: The present invention relates to novel peptide compounds derived from flagellin originating from Salmonelle enterica that exhibit an in vivo immune adjuvant activity.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: May 1, 2018
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, INSTITUT PASTEUR DE LILLE
    Inventor: Jean-Claude Sirard
  • Methods and pharmaceutical compositions for the treatment of bacterial infections
    Patent number: 9919029
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates to a Toll-like receptor (TLR) agonist for use in a method for the treatment of a bacterial infection in a subject in need thereof wherein the TLR agonist is administered to the subject in combination with at least one antibiotic.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: March 20, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Droit et de la Sante de Lille 2, Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Lille, Universite de Lille 1 Sciences et Technologies, ETH Zurich, Universidad de la Republica
    Inventors: Wolf-Dietrich Hardt, Patrick Kaiser, Jean-Claude Sirard, Christophe Carnoy, Delphine Fougeron, Jose Alejandro Chabalgoity, Natalia Munoz
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
    Publication number: 20170354709
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of acute exacerbation of chronic obstructive pulmonary disease. In particular, the present invention relates to a method of treating acute exacerbation of chronic obstructive pulmonary disease in a subject in need thereof comprising administering the subject with a therapeutically effective amount of a flagellin polypeptide.
    Type: Application
    Filed: December 23, 2015
    Publication date: December 14, 2017
    Inventors: Philippe GOSSET, Muriel PICHAVANT, Jean-Claude SIRARD, Bachirou KONE, Magdiel PEREZ-CRUZ
  • NOVEL IMMUNOADJUVANT FLAGELLIN-BASED COMPOUNDS AND USE THEREOF
    Publication number: 20170021015
    Abstract: The present invention relates to novel peptide compounds derived from flagellin originating from Salmonelle enterica that exhibit an in vivo immune adjuvant activity.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicants: INSERM (Institut National de la Santé et de la Recherche Médicale), INSTITUT PASTEUR DE LILLE
    Inventor: Jean-Claude SIRARD
  • Immunoadjuvant flagellin-based compounds and use thereof
    Patent number: 9527891
    Abstract: The present invention relates to novel peptide compounds derived from flagellin originating from Salmonella enterica that exhibit an in vivo immune adjuvant activity.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: December 27, 2016
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), INSTITUT PASTEUR DE LILLE
    Inventor: Jean-Claude Sirard
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20160151453
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates to a Toll-like receptor (TLR) agonist for use in a method for the treatment of a bacterial infection in a subject in need thereof wherein the TLR agonist is administered to the subject in combination with at least one antibiotic.
    Type: Application
    Filed: July 25, 2014
    Publication date: June 2, 2016
    Inventors: Wolf-Dietrich HARDT, Patrick KAISER, Jean-Claude SIRARD, Christophe CARNOY, Delphine FOUGERON, Jose Alejandro CHABALGOITY, Natalia MUNOZ
  • Methods and Pharmaceutical Compositions for the Treatment of Respiratory Tract Infections
    Publication number: 20140206601
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of respiratory tract infections. More particularly, the present invention relates to a TLR5 agonist for use in a method for treating a respiratory tract infection.
    Type: Application
    Filed: February 20, 2014
    Publication date: July 24, 2014
    Applicants: Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Jean-Claude Sirard, Jose A. Chabalgoity
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY TRACT INFECTIONS
    Publication number: 20130150286
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of respiratory tract infections. More particularly, the present invention relates to a TLR5 agonist for use in a method for treating a respiratory tract infection.
    Type: Application
    Filed: June 25, 2010
    Publication date: June 13, 2013
    Inventors: Jean-Claude Sirard, Jose A. Chabalgoity
  • Novel Immunoadjuvant Flagellin-Based Compounds and Use Thereof
    Publication number: 20110110962
    Abstract: The present invention relates to novel peptide compounds derived from flagellin originating from Salmonella enterica that exhibit an in vivo immune adjuvant activity.
    Type: Application
    Filed: June 23, 2009
    Publication date: May 12, 2011
    Inventor: Jean-Claude Sirard
  • Adjuvants
    Publication number: 20060257415
    Abstract: A method is provided for inducing the adaptive immune response of a patient to an antigen comprising administering to the patient an effective amount of a flagellin protein or peptide fragment thereof to induce an adaptive immune response to said antigen.
    Type: Application
    Filed: September 3, 2003
    Publication date: November 16, 2006
    Applicant: FONDATION EUROV ACC
    Inventors: Jean-Claude Sirard, Jean-Pierre Kraehenbuhl