Patents by Inventor Jean-Claude Souvie

Jean-Claude Souvie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and its application in the synthesis of agomelatine
    Patent number: 7470806
    Abstract: A process for the industrial synthesis of the compound of formula (I) Application in the synthesis of agomelatine.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: December 30, 2008
    Assignee: Les Laboratories Servier
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco
  • Crystalline form V of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7358395
    Abstract: Crystalline form V of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: April 15, 2008
    Assignee: Les Laboratories Servier
    Inventors: Gerard Coquerel, Julie Linol, Jean-Claude Souvie
  • Process for the synthesis of (2S)-indoline-2-carboxylic acid
    Patent number: 7323575
    Abstract: Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: January 29, 2008
    Assignee: Les Laboratories Servier
    Inventors: Jean-Claude Souvie, Jean-Pierre Lecouve
  • Process for the synthesis and crystalline form of agomelatine
    Publication number: 20080004352
    Abstract: A process for the industrial synthesis and new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: May 31, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Claude Souvie, Isaac Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien
  • Process for the synthesis and crytalline form of agomelatine
    Publication number: 20080004347
    Abstract: A process for the industrial synthesis and new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: May 30, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Claude Souvie, Isaac Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien
  • Process for the synthesis and crystalline form agomelatine
    Publication number: 20070197829
    Abstract: Process for the industrial synthesis and new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: April 6, 2007
    Publication date: August 23, 2007
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien
  • Process for the synthesis and crystalline form of agomelatine
    Patent number: 7250531
    Abstract: A process for the industrial synthesis and a new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: July 31, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco, Gilles Thominot, Geneviève Chapuis, Stéphane Horvath, Gérard Damien
  • Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
    Publication number: 20070135411
    Abstract: Process for the synthesis of ivabradine of formula (I): addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof. ? crystalline form of ivabradine hydrochloride. Medicinal products containing ? crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
    Type: Application
    Filed: January 18, 2007
    Publication date: June 14, 2007
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Michel Lerestif, Jean-Pierre Lecouve, Jean-Claude Souvie, Daniel Brigot, Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Process for the synthesis of (2S)-indoline-2-carboxylic acid
    Publication number: 20070112204
    Abstract: Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts.
    Type: Application
    Filed: January 5, 2007
    Publication date: May 17, 2007
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Claude Souvie, Jean-Pierre Lecouve
  • Method for the synthesis of s-indoline-2-carboxylic acid and application thereof in the synthesis of perindopril
    Patent number: 7196204
    Abstract: Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: March 27, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Souvie, Jean-Pierre Lecouve
  • Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
    Patent number: 7176197
    Abstract: Process for the synthesis of ivabradine of formula (I): addition salts with a pharmaceutically acceptable acid and hydrates thereof. ? crystalline form of ivabradine hydrochloride. Medicinal products containing the a crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: February 13, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Michel Lerestif, Jean-Pierre Lecouve, Jean-Claude Souvie, Daniel Brigot, Stéphane Horvath, Marie-Noëlle Auguste, Gérard Damien
  • Crystalline form V of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20060270877
    Abstract: Crystalline form V of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 30, 2006
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Gerard Coquerel, Julie Linol, Jean-Claude Souvie
  • Crystalline form III of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20060270876
    Abstract: Crystalline form III of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 30, 2006
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Gerard Coquerel, Julie Linol, Jean-Claude Souvie
  • Crystalline form IV of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Publication number: 20060270875
    Abstract: Crystalline form IV of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 30, 2006
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Gerard Coquerel, Julie Linol, Jean-Claude Souvie
  • Novel method for the synthesis of s-indoline-2- carboxylic acid and application thereof in the synthesis of perindopril
    Publication number: 20060183919
    Abstract: Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts.
    Type: Application
    Filed: April 7, 2004
    Publication date: August 17, 2006
    Inventors: Jean-Claude Souvie, Jean-Pierre Lecouve
  • Process for the synthesis of 1,3,4,5-tetrahydro-2H-3-benzazepin-2-one compounds, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
    Patent number: 7064200
    Abstract: Process for the synthesis of compounds of formula (I): wherein R1 and R2, which may be the same or different, each represent a linear or branched (C1–C8)alkoxy group or form, together with the carbon atom carrying them, a 1,3-dioxane, 1,3-dioxolane or 1,3-dioxepane ring. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: June 20, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Michel Lerestif, Jean-Pierre Lecouve, Jean-Claude Souvie, Daniel Brigot
  • Process for the synthesis of 1,3,4,5-tetrahydro-2H-3-benzazepin-2-one compounds. and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
    Publication number: 20050228178
    Abstract: Process for the synthesis of compounds of formula (I): wherein R1 and R2, which may be the same or different, each represent a linear or branched (C1-C8)alkoxy group or form, together with the carbon atom carrying them, a 1,3-dioxane, 1,3-dioxolane or 1,3-dioxepane ring. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof.
    Type: Application
    Filed: February 17, 2005
    Publication date: October 13, 2005
    Inventors: Jean-Michel Lerestif, Jean-Pierre Lecouve, Jean-Claude Souvie, Daniel Brigot
  • Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
    Publication number: 20050228177
    Abstract: Process for the synthesis of ivabradine of formula (I): addition salts with a pharmaceutically acceptable acid and hydrates thereof. ? crystalline form of ivabradine hydrochloride. Medicinal products containing the a crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
    Type: Application
    Filed: February 14, 2005
    Publication date: October 13, 2005
    Inventors: Jean-Michel Lerestif, Jean-Pierre Lecouve, Jean-Claude Souvie, Daniel Brigot, Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
  • Process for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and its application in the synthesis of agomelatine
    Publication number: 20050182267
    Abstract: A process for the industrial synthesis of the compound of formula (I) Application in the synthesis of agomelatine.
    Type: Application
    Filed: February 7, 2005
    Publication date: August 18, 2005
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco
  • Process for the synthesis and crystalline form of agomelatine
    Publication number: 20050182276
    Abstract: A process for the industrial synthesis and a new crystalline form of the compound of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: February 7, 2005
    Publication date: August 18, 2005
    Inventors: Jean-Claude Souvie, Isaac Gonzalez Blanco, Gilles Thominot, Genevieve Chapuis, Stephane Horvath, Gerard Damien