Patents by Inventor Jean F. Rossignol

Jean F. Rossignol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for converting crystalline erythromycin ethylsuccinate into stable amorphous erythromycin ethylsuccinate
    Patent number: 5118799
    Abstract: This invention relates to a process for converting crystalline erythromycin ethylsuccinate into stable amorphous erythromycin ethylsuccinate, and to the use of this stable amorphous ethylsuccinate in pharmaceutical compositions which may possibly contain pharmacologically acceptable excipients, surfactants and the like.
    Type: Grant
    Filed: October 27, 1989
    Date of Patent: June 2, 1992
    Assignee: Pharmacin Corporation
    Inventor: Jean F. Rossignol
  • Quinate salts of antimalarial phenanthrenemethanol compounds
    Patent number: 4818767
    Abstract: The compounds of formula (I) ##STR1## wherein R.sub.1 is hydrogen or an alkyl radical containing one to six carbon atoms and R.sub.2 is an alkyl radical containing one to six carbon atoms possess markedly increased activity against malaria-causing parasites. Pharmaceutical compositions and method of treatment of subjects with malaria are also disclosed.
    Type: Grant
    Filed: November 2, 1983
    Date of Patent: April 4, 1989
    Assignee: SmithKline Beckman Corporation
    Inventor: Jean F. Rossignol
  • Quinate salts of the antimalarial compound mefloquine
    Patent number: 4521424
    Abstract: The compound of formula (I) ##STR1## possesses markedly increased solubility under aqueous conditions and improved pharmacokinetic profile against malaria-causing parasites. Pharmaceutical compositions and method of treatment of subjects with malaria are also disclosed.
    Type: Grant
    Filed: February 27, 1984
    Date of Patent: June 4, 1985
    Assignee: SmithKline Beckman Corporation
    Inventor: Jean F. Rossignol
  • .beta.-Glycerophosphate salts of antimalarial phenanthrenemethanol compounds
    Patent number: 4507288
    Abstract: The compounds of formula (I) ##STR1## wherein R.sub.1 is hydrogen or an alkyl radical containing one to six carbon atoms and R.sub.2 is an alkyl radical containing one to six carbon atoms possess markedly increased activity against malaria-causing parasites. Pharmaceutical compositions and method of treatment of subjects with malaria are also disclosed.
    Type: Grant
    Filed: September 16, 1983
    Date of Patent: March 26, 1985
    Assignee: Smithkline Beckman Corporation
    Inventor: Jean F. Rossignol
  • Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
    Patent number: 4315018
    Abstract: The 2-benazmido-5-nitro-thiazole derivatives disclosed in U.S. Pat. No. 3,950,351 are effective against various species of cestodes: Taenia pisiformis, Dypilidium caninum, Echinococus granulosus and Moniezia expansa, and various species of nematodes: roundworms (Ancyslotoma spp.) and whipworms (Trichuris spp.).
    Type: Grant
    Filed: December 7, 1978
    Date of Patent: February 9, 1982
    Inventor: Jean F. Rossignol