Patents by Inventor Jean F. Schaefer

Jean F. Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human cell assay to determine effect of sample compounds on Col2 enhancer expression
    Publication number: 20040241755
    Abstract: This invention relates to human chondrocyte activity (growth)/differentiation/production of extracellular matrix) and to the effect of Sox9 transcription factor and Col2 enhancer as a measure for such activity. It also relates to a chimeric cell and assay utilizing such cell useful in predicting the effect of sample compounds on chondrocyte activity as measured by Sox9 and Col2 expression/activity.
    Type: Application
    Filed: June 2, 2003
    Publication date: December 2, 2004
    Applicant: Pfizer Inc.
    Inventors: Leonard Buckbinder, Jean F. Schaefer
  • ADAMTS polypeptides, nucleic acids encoding them, and uses thereof
    Publication number: 20020090373
    Abstract: The present invention relates to a member of the family of proteins known as ADAMTS proteins, the new member being designated ADAMTS-SI. The invention also relates to polynucleotides encoding ADAMTS-SI, antibodies to ADAMTS-SI, assays for studying the function of ADAMTS-SI, assays for determining agonists or antagonists of ADAMTS-SI, and to the use of ADAMTS-SI polypeptides or polynucleotides in diagnostic, biotherapeutic, or gene therapy methods.
    Type: Application
    Filed: October 5, 2001
    Publication date: July 11, 2002
    Inventors: Leonard Buckbinder, Peter G. Mitchell, Jean F. Schaefer, Roddy T. Walsh