Abstract: A method is provided for measuring the local hydraulic permeability, Lpi, of a sub-group of hollow fibres of a bundle of hollow fibres mounted in a tubular casing. The method comprises a step of placing the casing containing the bundle in a vertical position, the lateral opening of the casing being disposed toward the bottom, and sealing the lower end of the casing. A graduated, calibrated tube is applied in a vertical position over a portion of the upper cut surface of the bundle to form a sealed connection there between. A liquid is passed through the lateral opening of the casing at a defined flow rate, and the time required for the liquid to pass from a first graduation to a second graduation of the tube is measured.

Abstract: A method is provided for measuring the local hydraulic permeability, Lpi, of a sub-group of hollow fibres of a bundle of hollow fibres mounted in a tubular casing. The method comprises a step of placing the casing containing the bundle in a vertical position, the lateral opening of the casing being disposed toward the bottom, and sealing the lower end of the casing. A graduated, calibrated tube is applied in a vertical position over a portion of the upper cut surface of the bundle to form a sealed connection there between. A liquid is passed through the lateral opening of the casing at a defined flow rate, and the time required for the liquid to pass from a first graduation to a second graduation of the tube is measured.

Abstract: The invention relates to a bundle of hollow fibers intended to constitute the membrane of a device for treating blood or plasma by extracorporeal circulation, in which: the hydraulic permeability of the hollow fibers in the bundle is heterogeneous; and the ratio of the highest hydraulic permeability measured on some hollow fibers of the bundle to the lowest hydraulic permeability measured on other hollow fibers in the same bundle is at least about 5. The invention also relates to a method for producing such a bundle, and a device comprising such a bundle.

Abstract: The invention relates to a bundle of hollow fibers intended to constitute the membrane of a device for treating blood or plasma by extracorporeal circulation, in which: the hydraulic permeability of the hollow fibers in the bundle is heterogeneous; and the ratio of the highest hydraulic permeability measured on some hollow fibers of the bundle to the lowest hydraulic permeability measured on other hollow fibers in the same bundle is at least about 5.