Patents by Inventor Jean-Francois Fournier

Jean-Francois Fournier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrazolo[3,4-d]pyrimidines as mTOR inhibitors
    Patent number: 11731973
    Abstract: The invention relates to novel mTOR inhibitor compounds having the formula (I) or a pharmaceutically acceptable salt thereof, compositions comprising the mTOR inhibitor compounds, methods for producing the same, and the use thereof.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: August 22, 2023
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Laurence Clary, Jean-François Fournier, Gilles Ouvry, Yushma Bhurruth-Alcor, Etienne Thoreau, Loïc Tomas
  • MTOR inhibitor compounds
    Patent number: 11518767
    Abstract: The invention relates to novel mTOR inhibitor compounds having the general formula (I), to compositions comprising said mTOR inhibitor compounds, methods for producing same, and the use thereof in compositions as a drug.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: December 6, 2022
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Laurence Clary, Jean-François Fournier, Gilles Ouvry, Yushma Bhurruth-Alcor, Etienne Thoreau, Loïc Tomas
  • MTOR INHIBITOR COMPOUNDS
    Publication number: 20200317683
    Abstract: The invention relates to novel mTOR inhibitor compounds. The invention is characterized in that the mTOR inhibitor compounds have general formula (I). The invention also relates to compositions comprising said mTOR inhibitor compounds, methods for producing same, and the use thereof in compositions as a drug.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 8, 2020
    Inventors: Laurence CLARY, Jean-François FOURNIER, Gilles OUVRY, Yushma BHURRUTH-ALCOR, Etienne THOREAU, Loïc TOMAS
  • NOVEL MTOR INHIBITOR COMPOUNDS
    Publication number: 20200317679
    Abstract: The invention relates to novel mTOR inhibitor compounds. The invention is characterized in that the mTOR inhibitor compounds have general formula (I). The invention also relates to compositions comprising said mTOR inhibitor compounds, methods for producing same, and the use thereof in compositions as a drug.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 8, 2020
    Inventors: Laurence CLARY, Jean-François FOURNIER, Gilles OUVRY, Yushma BHURRUTH-ALCOR, Etienne THOREAU, Loïc TOMAS
  • Bale wrapper and round baler with such a device
    Patent number: 10674673
    Abstract: A bale wrapper and a round baler with such a device are described. The bale wrapper comprises a supply device, extending along the width of a bale chamber of a round baler, for the introduction of wrapping material. The supply device comprises a shielding layer, located on its upper side, for the upper-side shielding of a free end of the wrapping material, to be introduced into the bale chamber. In order to improve the supply operation of wrapping material into the bale chamber, the shielding layer comprises several shielding lips, located parallel to one another along the width of the bale chamber, which extend in the direction of an interior of the bale chamber.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: June 9, 2020
    Assignee: DEERE & COMPANY
    Inventors: Pascal Gresset, Jean-Francois Fournier
  • Recycling system and process of a methanol-to-propylene and steam cracker plant
    Patent number: 10427990
    Abstract: The present disclosure provides a system and method for recycling intermediate product streams of at least gasoline from the MTP plant to the steam cracker plant for processing with the feedstock of the steam cracker plant to generate a higher percentage of ethylene and propylene. The steam cracker feedstock can be ethane.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: October 1, 2019
    Assignee: TECHNIP FRANCE
    Inventors: Jean-Francois Fournier, Eric Stanley Wagner, Jean-Paul Laugier, Stéphane Haag, Thomas Wurzel, Martin Gorny
  • Heterocyclic compounds and use thereof in medicine and in cosmetics
    Patent number: 10246422
    Abstract: The invention relates to novel heterocyclic compounds of general formula (I), as well as their pharmaceutically acceptable salts, and their enantiomers. The invention also relates to the use thereof as a medicinal product, preferably in the prevention and/or treatment of inflammatory diseases with a neurogenic component or use thereof as a cosmetic. The compounds of the present invention act as antagonists of the CGRP-R receptor.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: April 2, 2019
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Jean-Francois Fournier, Laurence Clary, Etienne Thoreau
  • NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS
    Publication number: 20180050992
    Abstract: The invention relates to novel heterocyclic compounds of general formula (I), as well as their pharmaceutically acceptable salts, and their enantiomers. The invention also relates to the use thereof as a medicinal product, preferably in the prevention and/or treatment of inflammatory diseases with a neurogenic component or use thereof as a cosmetic. The compounds of the present invention act as antagonists of the CGRP-R receptor.
    Type: Application
    Filed: December 22, 2015
    Publication date: February 22, 2018
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Jean-Francois Fournier, Laurence Clary, Etienne Thoreau
  • Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
    Patent number: 9822107
    Abstract: The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring B, and the subscript r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: November 21, 2017
    Assignees: Merck Sharp & Dohme Corp., Merck Canada Inc.
    Inventors: Brian M. Andresen, Kenneth L. Arrington, Ryan D. Otte, John Michael Ellis, John W. Butcher, Alan B. Northrup, Joel S. Robichaud, Jacques Yves Gauthier, Jean-Francois Fournier
  • RECYCLING SYSTEM AND PROCESS OF A METHANOL-TO-PROPYLENE AND STEAM CRACKER PLANT
    Publication number: 20170253539
    Abstract: The present disclosure provides a system and method for recycling intermediate product streams of at least gasoline from the MTP plant to the steam cracker plant for processing with the feedstock of the steam cracker plant to generate a higher percentage of ethylene and propylene. The steam cracker feedstock can be ethane.
    Type: Application
    Filed: March 4, 2016
    Publication date: September 7, 2017
    Inventors: Jean-Francois FOURNIER, Eric Stanley WAGNER, Jean-Paul LAUGIER, Stéphane HAAG, Thomas Wurzel, Martin GORNY
  • THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS
    Publication number: 20160340351
    Abstract: The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring B, and the subscript r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
    Type: Application
    Filed: December 18, 2014
    Publication date: November 24, 2016
    Inventors: Brian M. Andresen, Kenneth L. Arrington, Ryan D. Otte, John Michael Ellis, John W. Butcher, Alan B. Northrup, Joel S. Robichaud, Jacques Yves Gauthier, Jean-Francois Fournier
  • Web wrap device
    Patent number: 9474212
    Abstract: A web wrap device is provided for a round baler. The device has a web carrier for pulling the web from a roll of web to a bale chamber. In a leading portion the web carrier has two elements at least one of which being moveable towards the other. The moveable element has a leading edge, which engages the web and is pulled by the tensioned web onto the other element, which increases the clamping effect. In addition a guard is provided to cover a knife during the wrapping mode, but to expose the knife to the web, when it should be cut.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: October 25, 2016
    Assignee: DEERE & COMPANY
    Inventors: Frédéric Paillet, Pascal Gresset, Jean Viaud, Michel Menetrier, Jean-François Fournier, Frederic Morel
  • Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors
    Patent number: 9353066
    Abstract: The invention provides certain substituted phenyl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: May 31, 2016
    Assignees: Merck Sharp & Dohme Corp., Merck Canada Inc.
    Inventors: Andrew M. Haidle, Jason Burch, Daniel Guay, Jacques Yves Gauthier, Joel Robichaud, Jean Francois Fournier, John Michael Ellis, Matthew Christopher, Solomon D. Kattar, Graham F. Smith, Alan B. Northrup
  • BALE WRAPPER AND ROUND BALER WITH SUCH A DEVICE
    Publication number: 20150305244
    Abstract: A bale wrapper and a round baler with such a device are described. The bale wrapper comprises a supply device, extending along the width of a bale chamber of a round baler, for the introduction of wrapping material. The supply device comprises a shielding layer, located on its upper side, for the upper-side shielding of a free end of the wrapping material, to be introduced into the bale chamber. In order to improve the supply operation of wrapping material into the bale chamber, the shielding layer comprises several shielding lips, located parallel to one another along the width of the bale chamber, which extend in the direction of an interior of the bale chamber.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 29, 2015
    Inventors: PASCAL GRESSET, JEAN-FRANCOIS FOURNIER
  • SUBSTITUTED PHENYL-SPLEEN TYROSINE KINASE (SYK) INHIBITORS
    Publication number: 20150232428
    Abstract: The invention provides certain substituted phenyl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
    Type: Application
    Filed: August 15, 2013
    Publication date: August 20, 2015
    Applicants: Merck Canada Inc., Merck Sharp & Dohme Corp.
    Inventors: Andrew M. Haidle, Jason Burch, Daniel Guay, Jacques Yves Gauthier, Joel Robichaud, Jean Francois Fournier, John Michael Ellis, Matthew Christopher, Solomon D. Kattar, Graham F. Smith, Alan B. Northrup
  • Aminopyrimidines as SYK Inhibitors
    Publication number: 20140243290
    Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
    Type: Application
    Filed: April 17, 2014
    Publication date: August 28, 2014
    Inventors: Michael D. Altman, Brian M. Andresen, Kenneth L. Arrington, Sathesh Bhat, Jason Burch, Kaleen Konrad Childers, Bernard Cote, Maria Emilia Di Francesco, Anthony Donofrio, Kristina Dupont-Gaudet, John Michael Ellis, Christian Fischer, Jean-Francois Fournier, Jacques Yves Gauthier, Jonathan Grimm, Daniel Guay, David Joseph Guerin, Andrew M. Haidle, Solomon D. Kattar, Sandra Lee Knowles, Chaomin Li, Jongwon Lim, Michelle R. Machacek, Matthew L. Maddess, Alan B. Northrup, Brendan M. O'Boyle, Ryan D. Otte, Alessia Petrocchi, Michael H. Reutershan, Joel S. Robichaud, Eric T. Romeo, Adam J. Schell, Tony Siu, Kerrie B. Spencer, Brandon M. Taoka, B. Wesley Trotter, Hyun Chong Woo, Hua Zhou
  • Aminopyrimidines as Syk inhibitors
    Patent number: 8735417
    Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: May 27, 2014
    Assignees: Merck Sharp & Dohme Corp., Merck Canada Inc.
    Inventors: Michael D. Altman, Kenneth L. Arrington, Jason Burch, Bernard Cote, Jean-Francois Fournier, Jacques Yves Gauthier, Solomon Kattar, Sandra Lee Knowles, Jongwon Lim, Michelle R. Machacek, Alan B. Northrup, Michael H. Reutershan, Joel S. Robichaud, Adam J. Schell, Kerrie B. Spencer
  • AMINOPYRIMIDINES AS SYK INHIBITORS
    Publication number: 20120309735
    Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
    Type: Application
    Filed: December 16, 2010
    Publication date: December 6, 2012
    Inventors: Michael D. Altman, Kenneth L. Arrington, Jason Burch, Bernard Cote, Jean-Francois Fournier, Jacques Yves Gauthier, Solomon Kattar, Sandra Lee Knowles, Jongwon Lim, Michelle R. Machacek, Alan B. Northrup, Michael H. Reutershan, Joel S. Robichaud, Adam J. Schell, Kerrie B. Spencer
  • AMINOPYRIMIDINES AS SYK INHIBITORS
    Publication number: 20120277192
    Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
    Type: Application
    Filed: December 15, 2010
    Publication date: November 1, 2012
    Inventors: Michael D. Altman, Brian M. Andresen, Kenneth L. Arrington, Sathesh Bhat, Jason Burch, Kaleen Konrad Childers, Bernard Cote, Maria Emilia Di Francesco, Anthony Donofrio, Kristina Dupont-Gaudet, John Michael Ellis, Christian Fischer, Jean-Francois Fournier, Jacques Yves Gauthier, Jonathan Grimm, Daniel Guay, David Joseph Guerin, Andrew M. Haidle, Solomon Kattar, Sandra Lee Knowles, Chaomin Li, Jongwon Lim, Michelle R. Machacek, Matthew L. Maddess, Alan B. Northrup, Brendan M. O'Boyle, Ryan D. Otte, Alessia Petrocchi, Michael H. Reutershan, Joel S. Robichaud, Eric Romeo, Adam J. Schell, Tony Siu, Kerrie B. Spencer, Brandon M. Taoka, B. Wesley Trotter, Hyun Chong Woo, Hua Zhou
  • AMINOPYRIMIDINES AS SYK INHIBITORS
    Publication number: 20110245205
    Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
    Type: Application
    Filed: December 15, 2010
    Publication date: October 6, 2011
    Inventors: Michael D. Altman, Brian M. Andresen, Kenneth L. Arrington, Sathesh Bhat, Jason Burch, Kaleen Konrad Childers, Bernard Cote, Maria Emilia Di Francesco, Anthony Donofrio, Kristina Dupont-Gaudet, John Michael Ellis, Christian Fischer, Jean-Francois Fournier, Jacques Yves Gauthier, Jonathan Grimm, Daniel Guay, David Joseph Guerin, Andrew M. Haidle, Solomon Kattar, Sandra Lee Knowles, Chaomin Li, Jongwon Lim, Michelle R. Machacek, Matthew L. Maddess, Alan B. Northrup, Brendan M. O'Boyle, Ryan D. Otte, Alessia Petrocchi, Michael H. Reutershan, Joel S. Robichaud, Eric Romeo, Adam J. Schell, Tony Siu, Kerrie B. Spencer, Brandon M. Taoka, B. Wesley Trotter, Hyun Chong Woo, Hua Zhou