Abstract: A method for refining a search is provided. Embodiments may include receiving a first speech signal corresponding to a first utterance and receiving a second speech signal corresponding to a second utterance, wherein the second utterance is a refinement to the first utterance. Embodiments may also include identifying information associated with the first speech signal as first speech signal information and identifying information associated with the second speech signal as second speech signal information. Embodiments may also include determining a first quantity of search results based upon the first speech signal information and determining a second quantity of search results based upon the second speech signal information.

Abstract: A natural language understanding system performs automatic unsupervised clustering of dialog data from a natural language dialog application. A log parser automatically extracts structured dialog data from application logs. A dialog generalizing module generalizes the extracted dialog data to generalization identifier vectors. A data clustering module automatically clusters the dialog data based on the generalization identifier vectors using an unsupervised density-based clustering algorithm without a predefined number of clusters and without a predefined distance threshold in an iterative approach based on a hierarchical ordering of the generalization.

Abstract: Multiple natural language understanding (NLU) interpretation selection models may be generated. The NLU interpretation selection models may include a generic NLU interpretation selection model that is not specialized for a specific set of NLU interpretations type and one or more specialized NLU interpretation selection models, each of which may be specific to a particular set of NLU interpretations type. The specialized NLU interpretation selection model(s) may be utilized to process natural language input data comprising data corresponding to their respective sets of NLU interpretations type(s). The generic NLU interpretation selection model may be utilized to process natural language input data comprising data that does not correspond to the sets of NLU interpretations type(s) associated with the specialized NLU interpretation selection model(s).

Abstract: A human-machine dialogue system is described which has multiple computer-implemented dialogue components. A user client delivers output prompts to a human user and receives dialogue inputs from the human user including speech inputs. An automatic speech recognition (ASR) engine processes the speech inputs to determine corresponding sequences of representative text words. A natural language understanding (NLU) engine processes the text words to determine corresponding NLU-ranked semantic interpretations. A semantic re-ranking module re-ranks the NLU-ranked semantic interpretations based on at least one of dialogue context information and world knowledge information. A dialogue manager responds to the re-ranked semantic interpretations and generates the output prompts so as to manage a dialogue process with the human user.

Abstract: A method for refining a search is provided. Embodiments may include receiving a first speech signal corresponding to a first utterance and receiving a second speech signal corresponding to a second utterance, wherein the second utterance is a refinement to the first utterance. Embodiments may also include identifying information associated with the first speech signal as first speech signal information and identifying information associated with the second speech signal as second speech signal information. Embodiments may also include determining a first quantity of search results based upon the first speech signal information and determining a second quantity of search results based upon the second speech signal information.

Abstract: The present invention provides HIV protease inhibitors of formulas I, IA, IB, Ib or II, or pharmaceutically acceptable salts thereof, wherein R2 may be, for example, 2-pyridyl-CH2—, 3-pyridyl-CH2—, 4-pyridyl-CH2—, a sulfonyl group as described in the formulas herein including benzenesulfonyl or thiophenesulfonyl groups, R2a—CO)—, R2a being selected from the group consisting of piperonyl, 2-pyranzinyl (unsubstituted or substituted with H, or an alkyl of 1 to 4 carbon atoms) or a picolylamine group as described herein, wherein R3 may be, for example, a phenyl group or diphenylmethyl group as described herein, and wherein Cx may be, for example, COOH, CONR5R6, CH2OH or CH2OR7.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention provides HIV protease inhibitors of formulas I, IA, IB, Ib or II, or pharmaceutically acceptable salts thereof, wherein R2 may be, for example, 2-pyridyl-CH2—, 3 -pyridyl-CH2—, 4-pyridyl-CH2—, a sulfonyl group as described in the formulas herein including benzenesulfonyl or thiophenesulfonyl groups, R2a—CO—, R2a being selected from the group consisting of piperonyl, 2-pyrazinyl (unsubstituted or substituted with H, or an alkyl of 1 to 4 carbon atoms) or a picolylamine group as described herein, wherein R3 may be, for example, a phenyl group or diphenylmethyl group as described herein, and wherein Cx may be, for example, COOH, CONR5R6, CH2OH or CH2OR7.

Abstract: A screen sharing and video conferencing method and system comprising a presenter device, one or more attendee devices and a streaming server for receiving and rebroadcasting video and audio streams from the presenter and the attendee devices. The presenter device and the attendee devices each comprise a browser-based video and audio streaming components configured to transmit camera video and microphone audio to the streaming server and playback video and audio streams from the streaming server. The presenter device further comprises an installed screen capture and system audio capture component configured to compress and transmit video data from a desktop and/or video source of the presenter device and to transmit system audio to the streaming server. The attendee devices further receive video and audio streams from the streaming server of camera, microphone, system audio and screen capture sources.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention provides HIV protease inhibitors of formulas I, IA, IB, Ib or II, or pharmaceutically acceptable salts thereof, wherein R2 may be, for example, 2-pyridyl-CH2—, 3-pyridyl-CH2—, 4-pyridyl-CH2—, a sulfonyl group as described in the formulas herein including benzenesulfonyl or thiophenesulfonyl groups, R2a—CO)—, R2a being selected from the group consisting of piperonyl, 2-pyranzinyl (unsubstituted or substituted with H, or an alkyl of 1 to 4 carbon atoms) or a picolylamine group as described herein, wherein R3 may be, for example, a phenyl group or diphenylmethyl group as described herein, and wherein Cx may be, for example, COOH, CONR5R6, CH2OH or CH2OR7.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.

Abstract: The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.

Abstract: The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.

Abstract: Dioxolane analogs of the following formula: wherein R1 and R2 are defined herein, are useful in the treatment of cancer. For example, the compounds can be used to treat patients with cancer in which the cancer cells are deficient in nucleoside or nucleoside base transporters.