Abstract: In a system and method of patient flow and treatment management, information regarding a patient admitted to a first unit of a patient treatment facility that is received into a first one of a number of user devices is dispatched to a server computer. Upon receipt of this patient information the server computer runs (desirably in real-time) a prediction application/algorithm that predicts an estimate of (1) the patient needing a resource in the first unit or a second unit of the facility, (2) a length of time before the patient needs the resource, and/or (3) an identity of the unit that has the needed resource. The server computer then dispatches (again, desirably in real-time) one or more of the predictions to one or more of the user devices, each of which receives and displays the prediction on a display thereof.

Abstract: Compounds of formula (I) are described herein The compounds can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some instances, the compounds can be used to treat obesity.

Abstract: The invention relates to a device (1) for cutaneously applying a substance (2), comprising: a patch (3) comprising said substance (2); and a single-use bracelet (4) comprising an irreversible attachment system allowing the substance (2) of the patch (3) to be maintained against the skin of a subject.

Abstract: Methods and apparatuses for restoration of human or animal bone anatomy, which may include introduction, into a bone of an expansible implant capable of expansion in a single determined plane, positioning the expansible implant in the bone in order to correspond the single determined plane with a bone restoration plane and opening out the expansible implant in the bone restoration plane. A first support surface and a second support surface spread tissues within bone. The embodiments of the invention may also include injecting a filling material around the implant.

Abstract: A method and automated system for assisting in the prognosis of the progress and for assisting in the diagnosis of Alzheimer's disease in patients suffering from mild cognitive impairment (MCI). Also provided is a method for training such a system related to identifying discriminant regions of the brain and using these regions to fine tune the assistance method, based on new known cases. Imaging data (PET or SPECT) is used, representing the cerebral activity in a plurality of spatial zones (voxels). The method then includes a normalization processing of the image data, and analysis of the cerebral activity values read in a selection of voxels forming at least one predetermined discriminant region, defined by its coordinates within a spatial reference system.

Abstract: The invention relates to a circuit for controlling a number of DC motors (M1, M2) capable of being controlled independently of one another, comprising, for each motor (M1, M2), an H-bridge (1A, 1B) made up of a first branch (3) and of a second branch (5), which bridge is intended for the control of the associated motor. According to the invention, the said second branches (5) of the H-bridges (1A, 1B) are produced in the form of two switches (7, 9) forming a branch common to all the H-bridges and rated to accept a current equivalent to the sum of the drive currents so that the said motors (M1, M2) can be controlled simultaneously and independently by applying associated control signals to the first branches (3).

Abstract: Dendritic or hyperbranched polyurethanes are prepared by 1) reacting diols or polyols having at least one tertiary nitrogen atom and at least two hydroxyl groups of differing reactivity toward isocyanate groups with diisocyanates or polyisocyanates to form an addition product, with the diols or polyols and diisocyanates or polyisocyanates being selected so that the addition product has, on average, one isocyanate group and more than one hydroxyl group or one hydroxyl group and more than one isocyanate group, 2) converting the addition product from step 1) into a polyaddition product by intermolecular reaction of the hydroxyl groups with the isocyanate groups, and with a reaction with a compound containing at least two hydroxyl groups, mercapto groups, amino groups or isocyanate groups also being able to be carried out first, 3) if desired reacting the polyaddition product from step 2) with a compound containing at least two hydroxyl groups, mercapto groups, amino groups or isocyanate groups.

Abstract: The invention relates to polynucleotide sequences comprising genetic variations of the PAR1 gene at positions 3090 and/or 3329. The occurrence of these variants in humans correlates with increased occurrence of particular cardiovascular disorders. The invention furthermore relates to methods for detecting said genetic variations for the purpose of patient diagnosis.

Abstract: The present invention relates to peptides derived from the proinflammatory cytokines, interleukin-1?, (IL1?) and tumor necrosis factor ?, (TNF?), and their use in human or veterinary therapy, such as to generally treat diseases linked to the overproduction of IL1? or TNF? as well as acute or chronic inflammatory diseases, rheumatoid arthritis, septic shock, autoimmune diabetes, graft rejection in the host, etc.

Abstract: Peptide of a size comprised between 5 and 40 amino acids, originating from a cytokine, in which at least one of its amino acids comprises at least one of its atoms separated by a distance d of less than 5 angströms from an atom of the receptor corresponding to said cytokine, the spacing d being evaluated on the basis of structural data, derivatives, immunogenic compounds comprising them, use of a peptide or peptide derivative or immunogenic compound for the preparation of a curative or preventative medicament intended for the treatment or prevention of diseases linked to an excess or to the presence of cytokines or for the treatment of an auto-immune disease and pharmaceutical compositions which contain at least one abovementioned peptide or peptide derivative or immunogenic compound as active ingredient.

Abstract: The present invention relates to an electronic device comprising a microphone, a loudspeaker, and a ringer, the device also comprising at least one inclination detector used for setting sound volume, the volume setting having at least two ranges, a first range (1) with a loud volume setting corresponding to circumstances in which the device is positioned horizontally and face-up, enabling it to operate in a hands-free mode, and a second range (2) with the volume set to low volume that is activated when the device departs from said horizontal position so as to operate in listener mode. Furthermore, the volume setting includes a third range defining a silent mode when the device is positioned horizontally and face-down.

Abstract: Circuit nodes are identified which, in unpowered mode, can be charged with positive or negative charges but cannot be discharged. Then protective elements are added to allow the discharge of these nodes. These elements do not affect the operation of the circuit in powered mode. Discharges of the two polarities are handled, positive and negative. The circuit is thus more resistant to ESD and passes CDM tests.

Abstract: A probe including at its distal extremity a tubular flexible sheath core supporting at least a winding forming a shock electrode and connected to a electrical conductor of connection extending in a internal lumen of the sheath core. The sheath core extends axially without a solution of continuity in the area supporting the winding. In particular, the sheath core comprises cavities to receive and hold conducting inserts, of homologous size with cavities formed locally close to the ends of the winding, the insert being connected to the interior side to the electrical conductor, and on the external side to the corresponding extremity of winding. A longitudinal slit connects the two cavities and allows, by elastic deformation of the sheath core, the introduction into the cavities and in the internal lumen of the unit formed by the final extremity of the electrical conductor beforehand equipped with its two inserts.

Abstract: The present invention relates to a method of identifying an increase in risk for type II Diabetes mellitus, venous thrombosis, or pulmonary embolism in a subject, wherein the presence of an amino acid exchange at position 286 from valine (Val) to alanine (Ala) in the EDG5 protein in a biological sample taken from the subject.

Abstract: The invention relates to a data transmission system comprising an antenna provided with a monopole radiating element held in place by an earth plane provided with a conducting surface. According to the invention, the radiating element is located facing the surface of the earth plane so as to interact with the latter in order to improve its performance.

Abstract: A geophysical measurement device is provided for exploration of natural resources of the floor in an aquatic domain. The device includes a frame designed to rest in a stable manner on the floor of the aquatic environment, at least one buoyancy caisson resting on the frame, measurement instruments. The measurement instruments including: at least one sensor making it possible to measure locally at least one of the components of the magnetic field; an analogue and/or digital data acquisition and processing device; and a source of energy supply of the sensor and of the data acquisition and processing device. The at least one sensor is contained inside the buoyancy caisson.

Abstract: This piece includes a rigid support frame (12) and an external skin (14) of soft appearance. The skin (14) has an exterior surface (24) intended to be placed opposite an occupant of the motor vehicle. The piece includes a foam layer (16) inserted between the support frame (12) and the exterior skin (14) and an assembly (18) for displaying at least one light signal on the exterior surface (24) of the skin. The display assembly (18) includes a device (30) for illuminating, through the skin, from the interior surface (26) of the skin, a chosen region (48) of the exterior surface (24). The illuminating device (30) is flexible so that it deforms when touched. It is fastened on the interior surface (26) the skin. A region (40) of the foam layer (16) is inserted between the support frame (12) and the illuminating device (30).

Abstract: The present invention relates to a device and method of assisting the piloting of a rotorcraft, the rotorcraft having a flight control (10) for controlling a rotor (20, 21) via at least one linkage (35), during which method an additional force is generated by at least one piloting assistance means (100) mechanically linked to the linkage (35), the additional force being a function of the position of the flight control (10) and of an instantaneous force as measured on the linkage (35).

Abstract: A method of preparing a transparent polymer material includes i) obtaining composite nanoparticles having mineral nanoparticles at least partially coated with at least one monomer and/or at least one polymer suitable for promoting physicochemical interactions at the interface between the mineral nanoparticles and a thermoplastic polycarbonate matrix, the mineral nanoparticles being surface-modified by the monomer and/or the polymer, either directly by grafting or directly by adsorption of the monomer and/or polymer onto the surface of the mineral nanoparticles; or via a coupling agent selected from a chlorosilane or an organosilane including a functional group that is capable of reacting by a radical pathway. The composite nanoparticles obtained in step i) are mixed with the thermoplastic polycarbonate matrix in the molten state to obtain the transparent polymer material.

Abstract: A process for the production of ene-amide derivatives represented by the formula (I) wherein R1 and R2 and R3 are independently a hydrogen atom, an alkyl, a cycloalkyl, a cycloalkylalkyl, an alkylaryl, an aryl, a heterocycle, a cyano, an alkoxy, an aryloxy, a carboxyl, a carbamoyl, —CONR5R6 (in which R5 and R6 are independently an alkyl, arylalkyl or aryl group said ring being substituted or not with a functional group or with R5) or —COOR5 group (in which R5 is an alkyl, alkylaryl or aryl group), said alkyl, cycloalkyl, cycloalkylalkyl, alkylaryl and aryl groups being substituted or not with a functional group or with R5; or R1 and R2 taken together, may form a ring (which terms includes mono-, di- and higher polycyclic ring systems); R4 is a hydrogen atom, an alkyl, an aryl, an alkylaryl, said groups are substituted or not with a halogen atom as Cl, Br, or F; X is an oxygen atom or a leaving group and m is an integer 1 or 2; when m is 1 then X is a leaving group; when m is 2 then X is a oxygen atom, whi