Abstract: Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/or of diseases related to the metabolism of lipids) or, alternatively, in cosmetic compositions.

Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.

Abstract: Process for the preparation of enantiomerically enriched compounds with Formula Ar—C(R1)—C(R2)-Z wherein Ar represents an optionally substituted (hetero)aryl group, R1 and R2, each independently, represent H, an alkyl, (hetero)aryl, dialky-lamino, amido, thioether, alkoxy or aryloxy group with the proviso that not both R1 and R2 represent H, or R1 and R2 form together with the C-atoms to which they are bound a (hetero)alkyl or (hetero) alkenyl ring and Z represents an electron withdrawing group, in which process a boronic acid derivate of Formula Ar—B(OR3)OR4 or its anhydride, wherein Ar is as described above and R3 and R4, each independently, represent H or an alkyl group, is reacted with an olefinic unsaturated compound with Formula R2—C?C—(R1)Z, wherein R1, R2 and Z are as described above, in the presence of a transition metal catalyst comprising a transition metal chosen from Cu and group VIII of the Periodic Table and an enantiomerically enriched ligand L, having the Formula (I) where Cn together with th

Abstract: The invention relates to novel 1-oxaspiro[2,5]octan-6-ol derivatives of general formula (I): and also to a method for preparing them, and to their use in pharmaceutical compositions for use in human or veterinary medicine, or in cosmetic compositions.

Abstract: The invention relates to novel 1-oxaspiro[2,5]octan-6-ol derivatives of general formula (1): 1