Patents by Inventor Jean Guy G. Gilles

Jean Guy G. Gilles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-idiotypic antibodies against factor VIII inhibitor and uses thereof
    Patent number: 7582296
    Abstract: The present invention discloses anti-idiotypic antibodies and fragments thereof against inhibitory Factor VIII anti-bodies, said inhibitory antibodies having an affinity for the C2 domain of Factor VIII. The anti-idiotypic antibodies of the present invention are able to completely neutralise in vitro and in an in vivo mouse model the inhibitory activity of FVIII inhibitors. The anti idiotypic antibodies of the present invention can be applied for the prevention, treatment or reduction of bleeding disorders of hemophilia patients with inhibitory antibody against the C2 domain of Factor VIII.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: September 1, 2009
    Assignee: D. Collen Research Foundation VZW
    Inventors: Jean Guy G. Gilles, Jean-Marie R. Saint-Remy, Marc G. Jacquemin