Patents by Inventor Jean Igolen

Jean Igolen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5393744
    Abstract: A compound having the following formula I: ##STR1## in which: R' represents a hydrogen atom or an azido group,alc represents an alkyl group of 1 to 4 carbon atoms, an alkoxy group of 1 to 4 carbon atoms or an amino group.
    Type: Grant
    Filed: January 29, 1990
    Date of Patent: February 28, 1995
    Assignee: Institut Pasteur
    Inventors: Tam Huynh Dinh, Catherine Gouyette, Bernadette Dupraz, Jean Igolen, Nathalie Savatier, Jean-Francois Nicolas, Francoise Barre-Sinoussi
  • Patent number: 5358937
    Abstract: The glycosylphospholipid nucleoside derivatives of the invention are based on the formula: ##STR1## wherein: R.sub.1 is a nucleoside derivative selected from the group consisting of 3'-azidothymidine (AZT); 2', 3'-dideoxythymidine (ddT); and 2'-deoxy-5-fluorouridine (dFU);R.sub.2 is a hexose or pentose sugar, with the exception of glucose when x is 1;A is a hydrogen atom or an alkyl or alkoxy chain containing from 5 to 20 carbon atoms, said alkyl or alkoxy chain having at its extremity a group selected from the group consisting of a hydrogen atom and an NR'R" group, wherein R' and R" represent hydrogen or an alkyl group of 1 to 4 carbon atoms;x is a number from 1 to 12;y is a number from 1 to 4; andz is 0 or 1; and further wherein:attachment of said hexose sugar is at position 1 or position 6 of said hexose sugar, and attachment of said pentose sugar is at position 1 or position 5 of said pentose sugar.
    Type: Grant
    Filed: September 21, 1992
    Date of Patent: October 25, 1994
    Assignee: Institut Pasteur
    Inventors: Tam Huynh Dinh, Catherine Gouyette, Jean Igolen, Robert Fauve, Luc Montagnier, Yvette Henin, Olivier Schwartz
  • Patent number: 4845205
    Abstract: The invention concerns 2,N.sup.6 -disubstituted and 2,N.sup.6 -trisubstituted adenosine nucleosides in which the sugar component is substituted at position 3' or position 5' by a phosphite or phosphoramidite group of the formula: ##STR1## R.sub.1 representing a lower alkyl or --(CH.sub.2).sub.n --CN with n being an integer between 1 and 4, and X representing a halogen or an amine group. These nucleosides make it possible to prepare sequences of nucleotides usable, in particular, as probes in the field of analyses and biological extractions.
    Type: Grant
    Filed: January 8, 1986
    Date of Patent: July 4, 1989
    Assignees: Institut Pasteur, Centre National de la Recherce Scientifique
    Inventors: Tam Huynh Dinh, Catherine Gouyette, Jean Igolen
  • Patent number: 4842996
    Abstract: The invention relates to a probe constituted by an oligonucleotide fragment of structure predetermined by the application envisaged, wherein at least a part of the adenine groups therein is replaced by modified adenine groups so that they can form three hydrogen bonds with the reactive groups of thymine or uracil. This probe is useful in the field of biological analyses and extractions.
    Type: Grant
    Filed: August 22, 1985
    Date of Patent: June 27, 1989
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Tam Huynh-Dinh, Jean Igolen