Patents by Inventor Jean J. Vasseur

Jean J. Vasseur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Backbone modified oligonucleotide analogues
    Patent number: 5610289
    Abstract: Therapeutic oligonucleotide analogues which have improved nuclease resistance and improved cellular uptake are provided. Replacement of the normal phosphorodiester inter-sugar linkages found in natural oligomers with four atom linking groups forms unique di- and poly- nucleosides and nucleotides useful in regulating RNA expression and in therapeutics. Methods of synthesis and use are also disclosed.
    Type: Grant
    Filed: April 7, 1994
    Date of Patent: March 11, 1997
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Phillip D. Cook, Yogesh S. Sanghvi, Jean J. Vasseur, Francoise Debart