Patents by Inventor Jean JACOVELLA

Jean JACOVELLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220347198
    Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.
    Type: Application
    Filed: July 7, 2022
    Publication date: November 3, 2022
    Inventors: Jean Jacovella, Jean-Paul Chappuis, Nathalie Sordello Wagner, Alexandre Kaoukhov, Michael Graeber, Laurence Salin, Michel Poncet, Philippe Briantais, Khaled Benkali
  • Patent number: 11234959
    Abstract: The present invention relates to a pharmaceutical composition comprising a compound of the avermectin family, preferably ivermectin, in a pharmaceutically acceptable carrier, for use in the treatment and/or prevention of hand eczema.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: February 1, 2022
    Assignee: GALDERMA HOLDING SA
    Inventors: Feriel Hacini-Rachinel, André Jomard, Jean Jacovella, Emmanuel Vial
  • Publication number: 20210177882
    Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.
    Type: Application
    Filed: February 18, 2021
    Publication date: June 17, 2021
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Nathalie SORDELLO WAGNER, Alexandre KAOUKHOV, Michael GRAEBER, Laurence SALIN, Michel PONCET, Philippe BRIANTAIS, Khaled BENKALI
  • Patent number: 10874682
    Abstract: The present invention relates to a composition comprising a pharmaceutically acceptable carrier, at least one compound of the avermectin family, and at least one non-steroidal anti-inflammatory compound. The present invention further provides such composition for use in the treatment and/or the prevention of rosacea.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: December 29, 2020
    Assignee: NESTLÉ SKIN HEALTH SA
    Inventors: Jean Jacovella, Olivier Roye, André Jomard
  • Patent number: 10653659
    Abstract: Compositions including a compound of the family of avermectins, preferably ivermectin, and an agonist compound for at least one of the retinoic acid receptors are described. The compositions are in particular used in the treatment of acne.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: May 19, 2020
    Assignee: GALDERMA S.A.
    Inventors: Jean-Paul Chappuis, Jean Jacovella
  • Publication number: 20200054599
    Abstract: The present invention relates to a pharmaceutical composition comprising a compound of the avermectin family, preferably ivermectin, in a pharmaceutically acceptable carrier, for use in the treatment and/or prevention of hand eczema.
    Type: Application
    Filed: November 2, 2017
    Publication date: February 20, 2020
    Inventors: Feriel HACINI-RACHINEL, André JOMARD, Jean JACOVELLA, Emmanuel VIAL
  • Publication number: 20200000835
    Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.
    Type: Application
    Filed: August 23, 2019
    Publication date: January 2, 2020
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Nathalie SORDELLO WAGNER, Alexandre KAOUKHOV, Michael GRAEBER, Laurence SALIN, Michel PONCET, Philippe BRIANTAIS, Khaled BENKALI
  • Patent number: 10463643
    Abstract: The use of a composition comprising a compound from the family of avermectins, preferably ivermectin, and doxycycline or one of the salts thereof that is pharmaceutically acceptable in the treatment and/or slowing of the appearance of the symptoms of rosacea is described.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: November 5, 2019
    Assignee: GALDERMA SA
    Inventor: Jean Jacovella
  • Patent number: 10376492
    Abstract: A compound is described that is selected from among macrocyclic lactones for treating and/or preventing a complication from a human papillomavirus infection. The complication to be treated and/or prevented can be selected from among malignant melanomas, skin carcinomas, in situ or invasive carcinomas, epidermoid carcinomas, Bowen's disease, head and neck cancers, upper aerodigestive tract cancers, laryngeal cancers, esophageal cancers, stomach cancers, oral papillomas, pharyngeal papillomas, laryngeal papillomas, esophageal papillomas, lung cancers, intravulval neoplasias, intravaginal neoplasias, intracervical neoplasias, cervical dysplasias, cervical carcinomas, penile cancer, intrapenile neoplasias, and in situ or invasive anal carcinomas.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: August 13, 2019
    Assignee: GALDERMA S.A.
    Inventor: Jean Jacovella
  • Publication number: 20190192545
    Abstract: The present invention relates to a composition comprising a pharmaceutically acceptable carrier, at least one compound of the avermectin family, and at least one non-steroidal anti-inflammatory compound. The present invention further provides such composition for use in the treatment and/or the prevention of rosacea.
    Type: Application
    Filed: August 4, 2017
    Publication date: June 27, 2019
    Applicant: NESTLÉ SKIN HEALTH SA
    Inventors: Jean JACOVELLA, Olivier ROYE, André JOMARD
  • Patent number: 10206939
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: February 19, 2019
    Assignee: Galderma S.A.
    Inventors: Jean Jacovella, Jean-Paul Chappuis, Alexandre Kaoukhov, Michael Graeber, Michel Poncet, Philippe Briantais, Laurence Salin
  • Publication number: 20180325859
    Abstract: Compositions including a compound of the family of avermectins, preferably ivermectin, and an agonist compound for at least one of the retinoic acid receptors are described. The compositions are in particular used in the treatment of acne.
    Type: Application
    Filed: November 19, 2015
    Publication date: November 15, 2018
    Inventors: Jean-Paul CHAPPUIS, Jean JACOVELLA
  • Publication number: 20180264021
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Alexandre KAOUKHOV, Michael GRAEBER, Michel PONCET, Philippe BRIANTAIS, Laurence SALIN
  • Publication number: 20180207188
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Application
    Filed: March 1, 2018
    Publication date: July 26, 2018
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Alexandre KAOUKHOV, Michael GRAEBER, Michel PONCET, Philippe BRIANTAIS, Laurence SALIN
  • Publication number: 20180177813
    Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.
    Type: Application
    Filed: February 22, 2018
    Publication date: June 28, 2018
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Nathalie SORDELLO WAGNER, Alexandre KAOUKHOV, Michael GRAEBER, Laurence SALIN, Michel PONCET, Philippe BRIANTAIS, Khaled BENKALI
  • Patent number: 9782425
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: October 10, 2017
    Assignee: Galderma S.A.
    Inventors: Jean Jacovella, Jean-Paul Chappuis, Alexandre Kaoukhov, Michael Graeber, Laurence Salin, Michel Poncet, Philippe Briantais
  • Publication number: 20170273931
    Abstract: The use of a composition comprising a compound from the family of avermectins, preferably ivermectin, and doxycycline or one of the salts thereof that is pharmaceutically acceptable in the treatment and/or slowing of the appearance of the symptoms of rosacea is described.
    Type: Application
    Filed: September 18, 2015
    Publication date: September 28, 2017
    Inventor: Jean JACOVELLA
  • Publication number: 20160184342
    Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.
    Type: Application
    Filed: July 8, 2014
    Publication date: June 30, 2016
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Nathalie SORDELLO WAGNER, Alexandre KAOUKHOV, Michael GRAEBER, Laurence SALIN, Michel PONCET, Philippe BRIANTAIS, Khaled BENKALI
  • Publication number: 20160175337
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Application
    Filed: December 17, 2015
    Publication date: June 23, 2016
    Inventors: Jean JACOVELLA, Jean-Paul CHAPPUIS, Alexandre KAOUKHOV, Michael GRAEBER, Michel PONCET, Philippe BRIANTAIS, Laurence SALIN
  • Publication number: 20160158263
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Application
    Filed: July 8, 2014
    Publication date: June 9, 2016
    Inventors: Jean JACOVELLA, Jian-Paul CHAPPUIS, Alexandre KAOUKHOV, Michael GRAEBER, Laurence SALIN, Michel PONCET, Philippe BRIANTAIS