Patents by Inventor Jean-Jacques Debernard

Jean-Jacques Debernard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microorganism of genus chrysosporium for use in preparing farnesyl transferase inhibitors
    Patent number: 5849724
    Abstract: A Chrysosporium strain No. CBS 123.95, mutants and derivatives thereof, and a method for preparing non-peptide compounds using said strain, are disclosed. Novel compounds of general formula (I), pharmaceutical compositions containing same, and the use of said compounds in anticancer treatments, are also disclosed.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: December 15, 1998
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean Leboul, Didier Van der Pyl, Jean-Jacques Debernard
  • Intermediates of peptide antagonists of neurotensin
    Patent number: 5747303
    Abstract: The invention is directed to a novel compound of formula ##STR1## in which R is a hydroxyl, alkyloxy, phenylalkyloxy or --NH--CH.sub.2 --COOH radical, R' and R" are identical and are each a hydroxy or methoxy radical and R'" represents a hydrogen, bromine, chlorine or iodine atom or a nitro radical. The invention is also directed to the salts of said compounds and their use.
    Type: Grant
    Filed: November 19, 1996
    Date of Patent: May 5, 1998
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Jacques Debernard, Catherine Dubertret, Gerard Helynck, Jean Leboul, Jean-Paul Martin
  • Peptides having farnesyl transferase inhibiting properties and strain of genus streptomyces for producing same
    Patent number: 5734013
    Abstract: A Steptomyces No. CBS 154.94 strain, mutants or derivatives thereof, and a method for preparing peptides using said strain, are disclosed. Novel peptides of general formula (1), pharmaceutical compositions containing same, and the use thereof in cancer therapy, are also disclosed.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: March 31, 1998
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Jacques Debernard, Thierry Flamant, Didier Van Der Pyl