Patents by Inventor Jean Lajeunesse

Jean Lajeunesse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING 2-AMINOTHIAZOLE-5-AROMATIC CARBOXAMIDES AS KINASE INHIBITORS
    Publication number: 20140179711
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: February 27, 2014
    Publication date: June 26, 2014
    Applicant: Bristol-Myers Squibb Company
    Inventors: Jean Lajeunesse, John D. DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Patent number: 8680103
    Abstract: The invention relates to a pharmaceutical composition of a crystalline monohydrate of the compound of formula (IV) wherein the crystalline monohydrate is characterized by certain unit cell parameters.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: March 25, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jean Lajeunesse, John D. DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • PROCESS FOR PREPARING 2-AMINOTHIAZOLE-5-AROMATIC CARBOXAMIDES AS KINASE INHIBITORS
    Publication number: 20120302750
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: July 31, 2012
    Publication date: November 29, 2012
    Inventors: Jean Lajeunesse, John D. DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Patent number: 8242270
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: August 14, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jean Lajeunesse, John D. DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein
    Patent number: 7968718
    Abstract: A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: June 28, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nachimuthu Soundararajan, Yuping Qiu, Wenhao Hu, David R. Kronenthal, Pierre Sirard, Jean Lajeunesse, Robert Droghini, Ramakrishnan Chidambaram, Xinhua Qian, Kenneth J. Natalie, Shawn K. Pack, Nathan Reising, Erqing Tang, Michael G. Fakes, Qi Gao, Feng Qian, Blisse J. Vakkalagadda, Chiajen Lai, Shan-Ming Kuang
  • PROCESS FOR PREPARING TRIAZOLE SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES AND NOVEL SALT FORMS PRODUCED THEREIN
    Publication number: 20100076191
    Abstract: A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.
    Type: Application
    Filed: August 27, 2009
    Publication date: March 25, 2010
    Inventors: NACHIMUTHU SOUNDARARAJAN, Yuping Qiu, Wenhao Hu, David R. Kronenthal, Pierre Sirard, Jean Lajeunesse, Robert Droghini, Ramakrishnan Chidambaram, Xinhua Qian, Kenneth J. Natalie, Shawn K. Pack, Nathan Reising, Erqing Tang, Michael G. Fakes, Qi Gao, Feng Qian, Blisse J. Vakkalagadda, Chiajen Lai, Shan-Ming Kuang
  • Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein
    Patent number: 7601715
    Abstract: A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: October 13, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nachimuthu Soundararajan, Yuping Qiu, Wenhao Hu, David R. Kronenthal, Pierre Sirard, Jean Lajeunesse, Robert Droghini, Ramakrishnan Chidambaram, Xinhua Qian, Kenneth J. Natalie, Shawn K. Pack, Nathan Reising, Erqing Tang, Michael G. Fakes, Qi Gao, Feng Qian, Blisse J. Vakkalagadda, Chiajen Lai, Shan-Ming Kuang
  • PROCESS FOR PREPARING 2-AMINOTHIAZOLE-5-AROMATIC CARBOXAMIDES AS KINASE INHIBITORS
    Publication number: 20090149650
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: December 23, 2008
    Publication date: June 11, 2009
    Inventors: Bang-Chi Chen, Roberto Droghini, Jean Lajeunesse, John D. Dimarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Patent number: 7491725
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: February 17, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jean Lajeunesse, John D. DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein
    Publication number: 20060293304
    Abstract: A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 28, 2006
    Inventors: Nachimuthu Soundararajan, Yuping Qiu, Wenhao Hu, David Kronenthal, Pierre Sirard, Jean Lajeunesse, Robert Droghini, Ramakrishnan Chidambaram, Xinhua Qian, Kenneth Natalie, Shawn Pack, Nathan Reising, Erqing Tang, Michael Fakes, Qi Gao, Feng Qian, Blisse Vakkalagadda, Chiajen Lai, Shan-Ming Kuang
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Publication number: 20060004067
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: July 29, 2005
    Publication date: January 5, 2006
    Inventors: Bang-Chi Chen, Roberto Droghini, Jean Lajeunesse, John DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Publication number: 20050215795
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: February 4, 2005
    Publication date: September 29, 2005
    Inventors: Bang-Chi Chen, Roberto Droghini, Jean Lajeunesse, John Dimarco, Michael Galella, Ramakrishnan Chidambaram