Patents by Inventor Jean Louis Viovy
Jean Louis Viovy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9840636Abstract: A straight, branched or cross-linked polymer, including, per 100 mol %: a) a mole fraction from 75% to 99.95% of monomer units from an N,N-dialkyl acrylamide; b) a mole fraction from 0.05% to 1% of monomer units from a monomer of formula (I): CH2=C(Ri)-C(?O)—O—[(CH2-CH(R2)-O]n-R3 (I); c) optionally a mole fraction higher than 0% to 24% either of monomer units from a monomer including a free strong acid function, partially or totally salified, or of monomer units from a monomer of formula (II): CH2=C(R4)-C(?O)—Y—(CH2)m-N(R5)(R6) (II); d) optionally a mole fraction higher than 0% to 1% of a diethylene or polyethylene cross-linking monomer. Also, a method for treating a surface made of a hydrophobic material, using the polymer, and an aqueous, hydro-organic or organic solution including the polymer for modifying interactions between the species contained the solution and the hydrophobic surface.Type: GrantFiled: March 21, 2014Date of Patent: December 12, 2017Assignees: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)Inventors: Jean-Louis Viovy, Olivier Braun
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Publication number: 20170335364Abstract: The invention relates to a method for detecting organisms in a liquid sample, comprising the provision of a capture area including particles in a liquid medium and subjected to a hydrodynamic flow, wherein the organisms to be detected are capable of binding to these particles, the method comprising the steps of: (a) circulating the sample through the capture area; (b) circulating a growth medium through the capture area; and (c) determining the presence, nature or concentration of organisms in the capture area; said particles being retained in the capture area as a fluidized bed for at least one part of these steps. The invention also relates to a system for implementing this method.Type: ApplicationFiled: October 23, 2015Publication date: November 23, 2017Inventors: Jean-Louis Viovy, Stephanie Descroix, Laurent Malaquin, Iago Pereiro, Lucile Alexandre
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Patent number: 9744513Abstract: A method for encapsulating or sorting colloidal objects, comprising the step of flowing said objects in a first flow stream partly or fully surrounded by at least one second flow stream in a channel comprising a narrow strait, wherein along an elongated part of the path of said first flow stream either (a) the bidimensional size of said first flow stream is smaller than the largest bidimensional size of at least some of said objects, either (b) the smallest unidimensional size of said first flow stream is smaller than the largest unidimensional size of at least some of said objects, either (c) said first flow stream is splitting, in the absence of said objects, into droplets with a volume smaller than the volume of at least some of said objects, or (d) said first flow stream would have in the absence of said particles, a shape that cannot entirely encompass some of said objects.Type: GrantFiled: September 22, 2008Date of Patent: August 29, 2017Inventors: Jean-Louis Viovy, Max Chabert
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Publication number: 20170173584Abstract: A microfluidic device for performing physical, chemical or biological treatment to at least one packet without contamination.Type: ApplicationFiled: December 28, 2016Publication date: June 22, 2017Applicants: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jean-Louis VIOVY, Max CHABERT, Kevin DORFMAN
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Patent number: 9658189Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: GrantFiled: May 2, 2016Date of Patent: May 23, 2017Assignees: Institute Curie, Centre National de la Recherche Scientifique (C.N.R.S)Inventors: Jean-Louis Viovy, Valessa Barbier
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Patent number: 9566558Abstract: The present invention concerns a microfluidic device (1) for performing physical, chemical or biological treatment to at least one packet without contamination.Type: GrantFiled: September 9, 2005Date of Patent: February 14, 2017Assignees: INSTITUT CURIE, CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUEInventors: Jean-Louis Viovy, Max Chabert, Kevin Dorfman
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Publication number: 20160238557Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: ApplicationFiled: May 2, 2016Publication date: August 18, 2016Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.)Inventors: Jean-Louis VIOVY, Valessa BARBIER
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Patent number: 9347915Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: GrantFiled: February 11, 2015Date of Patent: May 24, 2016Assignees: Institute Curie, Centre National de la Recherche Scientifique (C.N.R.S)Inventors: Jean-Louis Viovy, Valessa Barbier
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Publication number: 20160040028Abstract: A straight, branched or cross-linked polymer, including, per 100 mol %: a) a mole fraction from 75% to 99.95% of monomer units from an N,N-dialkyl acrylamide; b) a mole fraction from 0.05% to 1% of monomer units from a monomer of formula (I): CH2=C(Ri)-C(=0)-0-[(CH2-CH(R2)-0]n-R3 (I); c) optionally a mole fraction higher than 0% to 24% either of monomer units from a monomer including a free strong acid function, partially or totally salified, or of monomer units from a monomer of formula (II): CH2=C(R4)-C(=0)-Y-(CH2)m-N(R5)(R6) (II); d) optionally a mole fraction higher than 0% to 1% of a diethylene or polyethylene cross-linking monomer. Also, a method for treating a surface made of a hydrophobic material, using the polymer, and an aqueous, hydro-organic or organic solution including the polymer for modifying interactions between the species contained the solution and the hydrophobic surface.Type: ApplicationFiled: March 21, 2014Publication date: February 11, 2016Applicants: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6)Inventors: Jean-Louis VIOVY, Olivier BRAUN
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Publication number: 20150253285Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: ApplicationFiled: February 11, 2015Publication date: September 10, 2015Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)Inventors: Jean-Louis VIOVY, Valessa Barbier
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Publication number: 20150219650Abstract: The invention concerns a microfluidic system (1) comprising: at least one channel (2) for the flow of fluid having an inlet (4), an outlet (5) and a longitudinal axis (7) extending between the inlet (4) and the outlet (5), said channel (2) comprising a capture zone (3), and the cross section of the channel (2) orthogonal to the longitudinal axis (7) of the channel (2) increasing in size in the capture zone (3), from the inlet (4) towards the outlet (5) of the channel (2); and means (6) for applying a magnetic field having a decreasing intensity in the capture zone (3) of the channel (2), from the inlet (4) towards the outlet (5) of the channel. The invention also concerns a method for treating a sample that can be implemented with this system.Type: ApplicationFiled: September 6, 2013Publication date: August 6, 2015Inventors: Jean-Louis Viovy, Sanae Tabnaoui, Laurent Malaquin, Stéphanie Descroix
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Publication number: 20150191773Abstract: The present invention concerns a method of detecting macroions in a liquid medium contained in a space, the method including: a) submitting the liquid medium to a stimulating electrical field to induce formation of aggregates of macroions, the formed aggregates of macroions preferably not including any additional labeling agent, and b) measuring, in a detection zone of the space, spatial and/or temporal fluctuations within the liquid medium of at least one variable depending on the concentration of the macroions in the liquid medium, and c) determining, based on these fluctuations, the presence of the macroions, step c) preferably including processing by a time-dependent or space dependent analysis, more preferably by wavelet analysis, or by autocorrelation the fluctuations measured at step b).Type: ApplicationFiled: July 2, 2013Publication date: July 9, 2015Inventor: Jean-Louis Viovy
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Patent number: 8975328Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: GrantFiled: August 29, 2007Date of Patent: March 10, 2015Assignee: Institute CurieInventors: Jean-Louis Viovy, Valessa Barbier
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Publication number: 20140342373Abstract: The present invention concerns a microfluidic system comprising: a microchannel containing several elements of two non-miscible fluids, the microchannel comprising a droplet (30) containing magnetic particles (M), and a device for generating inside the microchannel magnetic field, said device comprising an activable magnetic element, the activable magnetic element comprising a tip (5,6), the microfluidic system being configured to transport the droplet by flow or by pressure difference.Type: ApplicationFiled: July 24, 2012Publication date: November 20, 2014Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jean-Louis Viovy, Laurent Malaquin, Stefano Begolo, AnaïS Ali Cherif, Stephanie Descroix
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Patent number: 8741661Abstract: A method including: a) providing a first well with a first layer of a first flowable material and a second layer of a second flowable material, and a second well with a first layer of a first flowable material different from the first flowable material of the first well, b) locating the flowable material inlet within the first layer, c) sampling a first volume of the first flowable material, d) displacing the flowable material inlet relative to the first well to locate the flowable material inlet within the second layer, e) sampling a second volume of the second flowable material, f) displacing the flowable material inlet relative to the first and second wells to locate the flowable material inlet within the first layer of the second well, and g) sampling or dispensing into the second well a third volume of the first flowable material of the second well.Type: GrantFiled: September 12, 2007Date of Patent: June 3, 2014Assignees: Institut Curie, Centre National de la Recherche ScientifiqueInventors: Jean-Louis Viovy, Max Chabert
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Patent number: 8545770Abstract: A method for treating the surface of a polymerio substrate, including the following steps: providing a first polymeric substrate; contracting at least one part of one face of the first substrate with some liquid solvent system, the liquid solvent system containing at least a first volatile compound and at least a second compound having a low molecular weight and able to swell and/or soften the polymeric material forming the face; letting at least the volatile compound to evaporate from the face of the first substrate and; contracting the so-treated face of first substrate with a third material.Type: GrantFiled: December 11, 2007Date of Patent: October 1, 2013Assignees: Institue Curie, Centre Nationale de Recherche Scientifique, Fluigent Paris-Biotech-Faculte de MedecineInventors: Jean-Louis Viovy, Jeremie Weber, Debjani Paul, Laurent Malaquin, Sandrine Miserere
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Publication number: 20110306041Abstract: A device for cell culture, in particular of neuronal cells, including: a substrate defining a first microfluidic chamber to be seeded with a first cell culture, and at least a second microfluidic chamber, a fluidic interconnection system connecting the first and second chambers and enabling cellular extensions, in particular axons, to extend from one chamber to the other, wherein the interconnection system of the device is made so as to promote the progression of at least one first type of cellular extension, the first and second types of extension being different either due to the microfluidic chamber from which they originate, or due to the type of cell of which they constitute an extension.Type: ApplicationFiled: October 12, 2009Publication date: December 15, 2011Applicants: CNRS-DAE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), INSTITUT CURIEInventors: Jean-Louis Viovy, Jean-Michel Peyrin, Bernard Brugg, Laure Saias, Paul Gougis, Maeva Vignes
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Publication number: 20110285042Abstract: A method for encapsulating or sorting colloidal objects, comprising the step of flowing said objects in a first flow stream partly or fully surrounded by at least one second flow stream in a channel comprising a narrow strait, wherein along an elongated part of the path of said first flow stream either (a) the bidimensional size of said first flow stream is smaller than the largest bidimensional size of at least some of said objects, either (b) the smallest unidimensional size of said first flow stream is smaller than the largest unidimensional size of at least some of said objects, either (c) said first flow stream is splitting, in the absence of said objects, into droplets with a volume smaller than the volume of at least some of said objects, or (d) said first flow stream would have in the absence of said particles, a shape that cannot entirely encompass some of said objects.Type: ApplicationFiled: September 22, 2008Publication date: November 24, 2011Inventors: Jean-Louis Viovy, Max Chabert
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Publication number: 20110212440Abstract: An integrated microsystem, comprising: a microchannel, a field generator to create a magnetic field in at least one first portion of the microchannel having a direction substantially collinear with the direction of flow in the portion of the microchannel, the magnetic field also presenting a gradient, wherein the microsystem additionally comprises a detection area in fluid connection with the microchannel,Type: ApplicationFiled: October 12, 2009Publication date: September 1, 2011Applicants: CNRS-DAE, INSTITUT CURIE, UNIVERSITE PIERRE ET MARIE CURIE, FLUIGENTInventors: Jean-Louis Viovy, Laure Saias, Jacques Goulpeau, Antoine-Emmanual Saliba, Laurent Malaquin
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Patent number: 7972561Abstract: The invention relates to a microfluidic device comprising at least one micro-channel connected at one end to an enclosed area, characterized in that it also comprises an inlet circuit and an outlet circuit connected to the enclosed area and between which the fluid can be discharged without any contact with the micro-channel, wherein at least one of said inlet and outlet circuits can be controlled in such a way that the pressure at the end of the micro-channel can be modified independently from the pressure at the other end of the micro-channel.Type: GrantFiled: May 19, 2004Date of Patent: July 5, 2011Assignees: Centre National de la Recherche, Institut CurieInventors: Jean-Louis Viovy, Claus Futterer, Nicolas Davis Minc, Jean Rossier, Jean-Hugues Codarbox